A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression. This mechanism includes potential targets for next-generation drug discovery ...
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Hematopoietic stem cells (HSCs) are a class of stem cells located in bone marrow. HSCs give rise to every type of blood cell—from the red blood cells that carry oxygen to the white blood cells of the immune system. Bone ...
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Via drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A steroid hormone, dehydroepiandrosterone ...
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Revealing surprising answers to a long-standing enigma about the brain target of the anti-obesity hormone leptin, neuroscientists at Tufts University School of Medicine have used CRISPR genome editing to identify a neural ...
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An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.
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For years, scientists have observed that when male and female mice eat the same high-fat diet, the males gain significantly more weight than the females. The reasons for this difference between sexes are not completely understood, ...
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A major step forward has been made by researchers at the University of St Andrews towards finding new treatments for Spinal Muscular Atrophy (SMA), the commonest genetic cause of infant death.
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Large doses of a sperm protein that is ineffective in infertile males can be injected directly into eggs to kick-start fertilization, giving couples hope of conceiving.
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Thanks to a new method of analysing ultrasound images, conventional scanners can be used for generating high-res images of blood vessels in tumours. This approach makes it easier to distinguish between different types of ...
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