https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Antiretroviral drugs for HIV infection have enabled most people living with the virus to live long and healthy lives. However, a small portion of people experience detectable—and worrisome—traces of the virus that causes AIDS despite strict adherence to long-term treatment regimens and the absence of symptoms. https://medicalxpress.com/news/2026-06-defective-hiv-persistent-blood-treatment.html Mon, 08 Jun 2026 05:00:07 EDT news699868442 Rare genetic variants known to cause cardiomyopathy, an inherited cause of a weak heart, can increase the risk of patients developing heart failure. However, new research from Mass General Brigham Heart and Vascular Institute and the Broad Institute of MIT and Harvard reveals that dapagliflozin, a medication used to treat type 2 diabetes, is particularly effective at reducing the risk in individuals who are genetically predisposed to developing heart failure. https://medicalxpress.com/news/2026-06-diabetes-drug-sharply-heart-failure.html Mon, 08 Jun 2026 05:00:01 EDT news699883926 A landmark Indian clinical trial has found that giving steroids in short bursts instead of continuously can halve early treatment-related deaths in children with leukemia without reducing their chances of being cured. The study led by the Indian Childhood Collaborative Leukemia (ICiCle) group, which includes University of Manchester researchers, treated over 3,000 children with acute B-cell precursor acute lymphoblastic leukemia (ALL) at six major centers across India. https://medicalxpress.com/news/2026-06-simple-leukemia-treatment-india-early.html Sun, 07 Jun 2026 19:30:01 EDT news699869041 Tracking the brain's blood flow during neurosurgery represents one of the most critical and challenging parts of the operation. A brief interruption can mean the difference between permanent damage and full recovery, but it's difficult to track blood flow across the surgical field. https://medicalxpress.com/news/2026-06-newly-view-brain-blood-surgery.html Sun, 07 Jun 2026 17:00:02 EDT news699634097 The first human clinical trial of a universal Sarbeco coronavirus vaccine, developed by the University of Cambridge and spin-out DIOSynVax (DVX) Ltd, has shown that the vaccine is safe and has no significant side effects. https://medicalxpress.com/news/2026-06-ai-universal-vaccine-human-trial.html Sun, 07 Jun 2026 15:20:01 EDT news699866842 A group of researchers at the Medical University of South Carolina (MUSC) has recently developed a new stem cell therapy with a remarkable ability to reverse new-onset type 1 diabetes (T1D) in a mouse model of the disease. The work is published in the journal Molecular Therapy. https://medicalxpress.com/news/2026-06-stem-cells-reverse-onset-diabetes.html Sun, 07 Jun 2026 08:00:01 EDT news699634341 The rods and cones in your eyes are responsible for helping you see, but what is responsible for helping them? Retinal pigment epithelium cells are their caretakers, but environmental, genetic and aging factors can strain them and make them less effective. This is known as age-related macular degeneration—a leading cause of blindness. https://medicalxpress.com/news/2026-06-lab-grown-aging-eye-reveals.html Sun, 07 Jun 2026 06:20:01 EDT news700029566 Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function. For decades, scientists believed that these drugs blocked HDAC enzymes, which drive cancer development by altering how genes are turned on and off. https://medicalxpress.com/news/2026-06-reconsidering-histone-deacetylase-inhibitors-cancer.html Sun, 07 Jun 2026 06:00:02 EDT news700029467 Chromosomal instability is a common feature in many solid tumors and is associated with greater aggressiveness. For years, its main contribution to cancer was thought to be driving the evolution of tumor genomes, causing cells to gain chromosomes with growth-promoting genes or lose chromosomes with tumor-suppressor genes. https://medicalxpress.com/news/2026-06-tumors-healthy-neighboring-cells-reveals.html Sat, 06 Jun 2026 16:20:01 EDT news699875179 A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months—the first vaccine created to protect against the disfiguring skin disease common in tropical regions of the world and gaining ground in the United States. https://medicalxpress.com/news/2026-06-leishmaniasis-vaccine-phase-trial-disease.html Sat, 06 Jun 2026 16:00:04 EDT news699978389 A combination of two widely available anti-rheumatic drugs offers the first effective and affordable treatment for patients with Sjögren's disease with systemic disease activity, according to new results from a clinical trial coordinated by UMC Utrecht. The study showed that treatment with leflunomide and hydroxychloroquine reduced disease activity in patients with moderate-to-severe disease while maintaining a favorable safety profile. https://medicalxpress.com/news/2026-06-common-arthritis-drugs-sjgren-disease.html Sat, 06 Jun 2026 15:40:03 EDT news699978269 A team of experimental oncology researchers at the University of Alberta is shedding light on how the deadly brain cancer glioblastoma spreads. In newly published research, they identify a potential treatment target to slow or even stop it. Glioblastoma is an aggressive form of cancer that affects 4 in 100,000 people, according to Brain Tumor Canada, with an average survival of 12 to 18 months. https://medicalxpress.com/news/2026-06-inhibit-brain-cancer-infiltration-mechanism.html Sat, 06 Jun 2026 14:00:05 EDT news699866873 The Biostatistics Unit at the Germans Trias i Pujol Research Institute (IGTP), in collaboration with researchers from several Catalan health care and research institutions, has published the DIVINE study database in Scientific Data. The journal specializes in publishing datasets and promotes the accessibility, proper documentation and reusability of these resources by the scientific community. https://medicalxpress.com/news/2026-06-cohort-patients-hospitalized-covid-scientific.html Sat, 06 Jun 2026 12:20:01 EDT news699874739 Autism spectrum disorder (ASD), commonly referred to as autism, is a neurodevelopmental condition characterized by differences in social interactions, communication, behavior and the processing of sensory stimuli. Notably, the experiences, aptitudes and needs of autistic people can vary significantly. https://medicalxpress.com/news/2026-06-autism-distinct-subtypes-based-brain.html Sat, 06 Jun 2026 09:40:01 EDT news699529113 In 2025, the European Medicines Agency approved two antibodies for Alzheimer's disease: lecanemab (LeqembiTM, from Biogen) and donanemab (Kisunla, from Eli Lilly and Co.), both based on immunotherapy (the use of molecules from the immune system to treat diseases). These antibodies, obtained in the laboratory, act against the Aβ peptide, a protein fragment that accumulates in the brains of patients with Alzheimer's disease. Elimination of this protein by the immune system helps slow the characteristic cognitive decline of the disease. https://medicalxpress.com/news/2026-06-antibody-fragment-hemorrhages-alzheimer-treatments.html Sat, 06 Jun 2026 08:40:01 EDT news699875268 A vaccine targeting a broad range of viruses that was designed using artificial intelligence had a "modest" effect on immune systems in a small, early trial, according to a new study. https://medicalxpress.com/news/2026-06-ai-universal-vaccine-humans-uk.html Sat, 06 Jun 2026 07:28:24 EDT news699949669 Non-invasive eye scans allow doctors a zoomed-in, three-dimensional look beneath the eye's surface without causing discomfort or pain to the patient. Used routinely in clinics worldwide, the scans produce detailed views of individual layers of the eye's interior to help diagnose conditions that threaten vision. But with that level of precision comes a flood of data—hundreds of images per scan that physicians have to review manually, a time-consuming process that is vulnerable to human error. https://medicalxpress.com/news/2026-06-ai-tools-eye-doctors-retinal.html Fri, 05 Jun 2026 18:00:02 EDT news699881657 A group of eating behavior and metabolism experts from across Europe have published a Perspective article in the journal Science examining the limitations of current evidence on ultraprocessed foods (UPFs). https://medicalxpress.com/news/2026-06-experts-highlight-limits-evidence-ultraprocessed.html Fri, 05 Jun 2026 17:00:01 EDT news699876111 Most folks know intermittent fasting helps with weight loss, usually by limiting your daily eating window or cutting calories a couple of times a week. But does your age change how well this works for you—and might there be some hidden dangers? https://medicalxpress.com/news/2026-06-fasting-waistlines-exposing-dieters.html Fri, 05 Jun 2026 15:20:03 EDT news699871353 How we sleep may have lasting impacts on our brain health as we age. A new University of Arizona study has found that several common sleep behaviors may be linked to signs of brain aging. https://medicalxpress.com/news/2026-06-struggle-common-habits-brain-aging.html Fri, 05 Jun 2026 14:40:01 EDT news699887521 Infections by hantaviruses are rare but dangerous, killing 30–40% of infected people. When cases occur, public health officials need rapid, detailed information about the virus to identify the strain and its origin, so they can stop others from being exposed to the disease. Whole genome sequencing is an integral part of this work, though the genomes of these viruses are difficult to sequence using existing approaches. https://medicalxpress.com/news/2026-06-hantavirus-sequencing-tool-genomes-hard.html Fri, 05 Jun 2026 14:20:04 EDT news699882301 Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body's key cancer-fighters, according to new UCLA research. https://medicalxpress.com/news/2026-06-creatine-supercharge-immune-cells-key.html Fri, 05 Jun 2026 14:00:02 EDT news699881579 AI is already boosting positive outcomes in health care and holds promise for delivering many more. It is important, however, that deployment of AI tools—especially in a life-or-death health care setting—proceeds at a thoughtful and measured pace, cautions Shengpu Tang, assistant professor of computer science at Emory University. https://medicalxpress.com/news/2026-06-ai-sepsis-inflate-results-overtreatment.html Fri, 05 Jun 2026 13:40:03 EDT news699880623 Many repetitive regions of the genome have been considered "junk DNA" because the available technologies did not allow them to be studied at sufficient resolution. This is the case for the SST1/NBL2 macrosatellites, considered irrelevant and, until now, virtually invisible, which may have a more complex and decisive biological role than previously thought in nuclear organization, genome regulation, chromosomal instability and even cancer. https://medicalxpress.com/news/2026-06-hidden-junk-dna-regions-cancer.html Fri, 05 Jun 2026 13:20:04 EDT news699873009 Inside the brain is a dense network of neurons that receive, process, and relay information. The synapse, where neurons meet, is the epicenter of this communication. Neurons that send information, called presynaptic neurons, hold tiny packages of neurotransmitters—waiting for a chemical signal from the brain to be released. How this system is regulated by the brain during periods of learning has, until now, been out of reach. https://medicalxpress.com/news/2026-06-brain-cellular-3d-reveal-synapses.html Fri, 05 Jun 2026 13:00:01 EDT news699880261 A randomized clinical trial conducted across five countries in 47 pediatric emergency departments, including Ann & Robert H. Lurie Children's Hospital in Chicago, established that both commonly used IV fluids for treating septic shock—balanced crystalloid fluid and 0.9% saline—are equally safe and effective. Results were published in the New England Journal of Medicine. https://medicalxpress.com/news/2026-06-common-iv-fluids-equally-septic.html Fri, 05 Jun 2026 12:40:03 EDT news699879721 Working with mouse models, research led by the University of Michigan has revealed previously hidden biology of how touch-sensitive hairs create itching sensations. This fundamental discovery opens new avenues to better understand and potentially address human health conditions characterized by persistent itchiness. https://medicalxpress.com/news/2026-06-peach-fuzz-clues-chronic-treatments.html Fri, 05 Jun 2026 12:20:02 EDT news699879601 Mounting evidence links extreme heat to preterm (often called premature) birth, low birth weight, and stillbirth, indicating that rising temperatures are contributing to worse health outcomes for pregnant people and newborns. Preterm birth is already a leading cause of infant illness and death worldwide, with an estimated 12 to 15 million babies born too early each year, meaning even modest increases in heat-related risk could have substantial global consequences. https://medicalxpress.com/news/2026-06-dose-aspirin-offset-premature-birth.html Fri, 05 Jun 2026 12:00:04 EDT news699878701 An irregular heartbeat, or arrhythmia, leads to inefficient pumping of blood by the heart, which then prevents blood and oxygen from getting to the body's other organs. When blood and oxygen flow poorly to the brain, the risk of stroke and cognitive decline increases. https://medicalxpress.com/news/2026-06-triggered-arrhythmia-reveals-rapid-brain.html Fri, 05 Jun 2026 11:40:06 EDT news699877621 A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that early administration of immunotherapy with standard antifungal treatment improved outcomes and largely alleviated immune system paralysis caused by fungal lung infections in preclinical models. These findings could herald new clinically relevant strategies for treating a variety of life-threatening invasive fungal pneumonias, which disproportionately affect immunocompromised cancer patients. https://medicalxpress.com/news/2026-06-early-immunotherapy-aids-potentially-fatal.html Fri, 05 Jun 2026 11:20:07 EDT news699876073