https://medicalxpress.com/biomedical-technology-news/ en-us Latest medical news and research in Laboratory medicine Weill Cornell Medicine investigators have developed a new AI-based method to assess patients with a form of blood cancer called myelodysplastic neoplasms. The method, published June 30 in Leukemia, compares the physical locations and morphometric (size and shape) characteristics of every hematopoietic cell in a patient's bone marrow sample with those in healthy bone marrow to generate a score that reflects disease severity. https://medicalxpress.com/news/2026-07-human-bone-marrow-yields-tool.html Mon, 20 Jul 2026 12:00:05 EDT news703766221 For decades, pathologists have diagnosed and graded breast cancer by looking at tissue samples under a microscope, searching for telltale signs of disorder in the structure of cells and tissues. Now, researchers at Columbia and their collaborators have developed a new computational approach that transforms those visual patterns into quantitative measurements, potentially improving how clinicians predict breast cancer outcomes and choose therapies. https://medicalxpress.com/news/2026-07-topology-based-biomarkers-breast-cancer.html Sun, 19 Jul 2026 17:00:03 EDT news703688103 A study led by researchers at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), the University of Cambridge and others has identified a set of plasma proteins that could be used to diagnose and monitor patients with metabolic dysfunction-associated steatotic liver disease (MASLD). It was published today in Nature Metabolism. https://medicalxpress.com/news/2026-07-molecular-liver-disease.html Wed, 15 Jul 2026 15:40:03 EDT news703341045 The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk. Now, a simplified machine-learning version of this equation has been shown in a study of millions of U.S. adult and child blood samples to match the accuracy of the original—making it broadly accessible. The findings and code were published in JAMA Cardiology. https://medicalxpress.com/news/2026-07-machine-equation-accurately-ldl-cholesterol.html Wed, 15 Jul 2026 11:00:21 EDT news703229528 Allergies can be minor or life-threatening, and current diagnostic blood tests are not always adequate for determining which substances patients need to avoid to prevent a reaction. https://medicalxpress.com/news/2026-07-allergy-antibodies-trigger-reactions.html Wed, 15 Jul 2026 10:20:09 EDT news703325984 A blood test may predict if apparently healthy older adults are likely to develop Alzheimer's symptoms in the next five or 10 years, researchers reported Wednesday. https://medicalxpress.com/news/2026-07-blood-healthy-people-high-alzheimer.html Wed, 15 Jul 2026 04:21:48 EDT news703308046 A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged about the extent to which such tests can accurately predict whether a cognitively healthy individual will develop cognitive impairment—a key symptom of Alzheimer's disease. https://medicalxpress.com/news/2026-07-blood-based-symptoms-alzheimer-decade.html Wed, 15 Jul 2026 00:00:01 EDT news703229479 With the aid of physical forces—in this case, sound—it is possible to actively steer the formation of engineered tissue. For example, sound waves can be used to create functional vascular networks with blood vessel-like structures in vitro. Scientists at the Center for Molecular Biology of Heidelberg University have demonstrated this through their methodology for acoustic manipulation. The team led by Junior Professor Dr. Daniela Duarte Campos also defines quality requirements for generating complex vascularized 3D tissue containing multiple cell types that is relevant, for example, to biomedical studies. https://medicalxpress.com/news/2026-07-cultured-cells-vessel-networks-week.html Tue, 14 Jul 2026 13:20:02 EDT news703250302 Information processing using living organisms is an important area of biotechnology that has already been explored in previous studies. https://medicalxpress.com/news/2026-07-bacterial-responses-plasma-mild-severe.html Sat, 11 Jul 2026 08:00:01 EDT news702647017 Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood cancer acute myeloid leukemia. The study, published in the journal Nature, shows that changes in the regulation of genes within cells can help explain variation in the disease and influence prognosis and treatment choices. https://medicalxpress.com/news/2026-07-epigenetic-deeper-insight-leukemia.html Thu, 09 Jul 2026 10:00:08 EDT news702806731 A research team led by Minyoung Lee and Sunggyu Park of The Korea Institute of Materials Science (KIMS) Bio & Health Materials Research Division has developed a plasmonic-based liquid biopsy platform capable of ultrasensitive detection of KRAS mutations in the blood and urine of patients with early-stage colorectal cancer. https://medicalxpress.com/news/2026-07-plasmonic-liquid-biopsy-platform-early.html Thu, 09 Jul 2026 09:20:11 EDT news702802152 As people age, so do their stem cells. Scientists have known for years that the stem cells that go on to become blood cells show significant signs of aging that sometimes lead to leukemia, excessive blood clotting and other diseases. https://medicalxpress.com/news/2026-07-parent-blood-cells-buffer-effects.html Wed, 08 Jul 2026 14:20:04 EDT news702729343 The rise of automation and AI has raised fears about job loss, but smart tools can also train workers rather than replace them. Meanwhile, a chronic shortage of trained personnel limits the reach of health care in both developing and developed countries. https://medicalxpress.com/news/2026-07-device-access-high-diagnostic.html Tue, 07 Jul 2026 12:20:07 EDT news702639072 A paper published in the journal Biomarker Research by a cross-university team led by Queen Mary University of London researchers validates the use of a noninvasive brush biopsy test that can detect oral cancer within one hour. https://medicalxpress.com/news/2026-07-oral-cancer-hour.html Mon, 06 Jul 2026 15:00:02 EDT news702563805 Emerging discoveries in liquid biomarker research promise to transform the early detection, diagnosis and treatment monitoring of colorectal cancer (CRC), according to a new study, offering less invasive alternatives to traditional methods that often require surgical interventions or tissue biopsies. https://medicalxpress.com/news/2026-07-biomarker-colorectal-cancer.html Mon, 06 Jul 2026 08:40:02 EDT news702543874 Northwestern Medicine scientists have discovered that one of the body's most fundamental biological processes—how red blood cells are made—works differently in humans than previously thought, according to a new study published in Nature Genetics. The findings overturn decades of assumptions based largely on animal research, said study senior author Peng Ji, MD, Ph.D., the Marie A. Fleming Research Professor of Pathology. https://medicalxpress.com/news/2026-07-human-red-blood-cells-central.html Thu, 02 Jul 2026 13:40:08 EDT news702217382 Small loops of genetic material may be strong indicators of imminent Alzheimer's disease (AD) symptoms. In a new study published in Nature Medicine, researchers showed that elevated levels of certain circular RNAs (circRNAs) in the blood nearly tripled patients' risk of developing symptoms, suggesting these molecules are more sensitive to symptom onset than traditional AD biomarkers. https://medicalxpress.com/news/2026-07-biomarker-diagnostic-blood-alzheimer.html Wed, 01 Jul 2026 13:40:03 EDT news702128101 Research by the Barcelona Institute for Biomedical Research (IIBB), part of the Spanish National Research Council (CSIC), and the Institut de Recerca Sant Pau (IR Sant Pau) provides some of the first evidence that psychological therapies act as biological stimuli that induce molecular responses measurable through blood biomarkers. https://medicalxpress.com/news/2026-06-blood-biomarkers-response-psychotherapy-patients.html Tue, 30 Jun 2026 13:00:09 EDT news702036601 Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more likely to return even when scans appear reassuring. The sensitive blood test focuses on KRAS, a genetic mutation that drives more than 90% of pancreatic cancers. The findings come as a new revolutionary drug targeting KRAS is showing substantial survival benefits and nearing FDA review. https://medicalxpress.com/news/2026-06-blood-hidden-pancreatic-cancer-treatment.html Tue, 30 Jun 2026 10:00:01 EDT news701966453 Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study sheds light on changes in the biological processes of WTC patients with PTSD that may explain why PTSD is associated with a variety of chronic diseases that ultimately contribute to aging. https://medicalxpress.com/news/2026-06-faster-aging-chronic-disease-linked.html Fri, 26 Jun 2026 12:00:03 EDT news701691123 Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples. https://medicalxpress.com/news/2026-06-genai-misalignment-virtual-real.html Fri, 26 Jun 2026 11:40:03 EDT news701690781 Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm. The new method enables a detailed analysis even with small samples and allows the detection of the largest number of potential biomarkers identified to date; this advance could help diagnose male infertility and develop future clinical solutions. The paper is published in the journal Cells. https://medicalxpress.com/news/2026-06-methodology-biomarkers-male-infertility.html Thu, 25 Jun 2026 11:20:01 EDT news701603238 A new collaborative study by Tel Aviv University and Sheba Medical Center marks a significant advance toward noninvasive blood testing, one of the most significant unmet needs in the market. The researchers have developed an artificial intelligence–based system capable of assessing hemoglobin levels and red blood cell counts using a short video recording of the blood vessels in the eye's conjunctiva, the transparent membrane covering the white part of the eye, without the need for a needle prick or blood draw. https://medicalxpress.com/news/2026-06-video-tiny-vessels-eye-ai.html Thu, 25 Jun 2026 10:00:09 EDT news701598662 Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes—the cells responsible for heart contraction. https://medicalxpress.com/news/2026-06-technology-reveal-heart-generates-cells.html Wed, 24 Jun 2026 18:20:05 EDT news701531998 For children with suspected inflammatory bowel disease (IBD), a chronic, relapsing condition of the gastrointestinal tract, getting the right diagnosis relies on a combination of clinical evaluation, imaging, endoscopy and histopathology. Identifying reliable blood-based diagnostic tools remains an important unmet clinical need. https://medicalxpress.com/news/2026-06-blood-protein-signature-invasive-diagnosis.html Tue, 23 Jun 2026 18:20:01 EDT news701450101 "Primary teeth provide a unique timeline of early life," Dr. Synnøve Stokke Jensen at the University of Bergen says. "They preserve information from pregnancy and childhood that cannot be captured retrospectively in other ways. This allows us to investigate environmental exposures during sensitive developmental periods with unprecedented detail." https://medicalxpress.com/news/2026-06-naturally-baby-teeth-key-early.html Tue, 23 Jun 2026 09:20:01 EDT news701423941 Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted with unfamiliar inputs. Suppose you train a neural network to distinguish among African mammals. If you then present it with an image of a South American jaguar—an animal it has never encountered—the model cannot say "unknown." Instead, it may confidently declare the jaguar to be a leopard. https://medicalxpress.com/news/2026-06-framework-ai-trustworthy-cancer-subtyping.html Tue, 23 Jun 2026 05:00:03 EDT news701347110 Mount Sinai researchers have discovered blood RNA biomarkers that offer a promising, minimally invasive approach for earlier diagnosis of Alzheimer's disease, according to findings published in Nature Communications. https://medicalxpress.com/news/2026-06-rna-biomarkers-simple-blood-earlier.html Mon, 22 Jun 2026 13:40:20 EDT news701353239 Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, pathology—the study of disease processes—is essentially based on the time-consuming examination of thin tissue sections, which are stained and then viewed under a microscope. https://medicalxpress.com/news/2026-06-ct-tissue-images-virtually-3d.html Sun, 21 Jun 2026 11:00:01 EDT news701017573