https://medicalxpress.com/biomedical-technology-news/ en-us Latest medical news and research in Laboratory medicine Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more likely to return even when scans appear reassuring. The sensitive blood test focuses on KRAS, a genetic mutation that drives more than 90% of pancreatic cancers. The findings come as a new revolutionary drug targeting KRAS is showing substantial survival benefits and nearing FDA review. https://medicalxpress.com/news/2026-06-blood-hidden-pancreatic-cancer-treatment.html Tue, 30 Jun 2026 10:00:01 EDT news701966453 Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study sheds light on changes in the biological processes of WTC patients with PTSD that may explain why PTSD is associated with a variety of chronic diseases that ultimately contribute to aging. https://medicalxpress.com/news/2026-06-faster-aging-chronic-disease-linked.html Fri, 26 Jun 2026 12:00:03 EDT news701691123 Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples. https://medicalxpress.com/news/2026-06-genai-misalignment-virtual-real.html Fri, 26 Jun 2026 11:40:03 EDT news701690781 Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm. The new method enables a detailed analysis even with small samples and allows the detection of the largest number of potential biomarkers identified to date; this advance could help diagnose male infertility and develop future clinical solutions. The paper is published in the journal Cells. https://medicalxpress.com/news/2026-06-methodology-biomarkers-male-infertility.html Thu, 25 Jun 2026 11:20:01 EDT news701603238 A new collaborative study by Tel Aviv University and Sheba Medical Center marks a significant advance toward noninvasive blood testing, one of the most significant unmet needs in the market. The researchers have developed an artificial intelligence–based system capable of assessing hemoglobin levels and red blood cell counts using a short video recording of the blood vessels in the eye's conjunctiva, the transparent membrane covering the white part of the eye, without the need for a needle prick or blood draw. https://medicalxpress.com/news/2026-06-video-tiny-vessels-eye-ai.html Thu, 25 Jun 2026 10:00:09 EDT news701598662 Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes—the cells responsible for heart contraction. https://medicalxpress.com/news/2026-06-technology-reveal-heart-generates-cells.html Wed, 24 Jun 2026 18:20:05 EDT news701531998 For children with suspected inflammatory bowel disease (IBD), a chronic, relapsing condition of the gastrointestinal tract, getting the right diagnosis relies on a combination of clinical evaluation, imaging, endoscopy and histopathology. Identifying reliable blood-based diagnostic tools remains an important unmet clinical need. https://medicalxpress.com/news/2026-06-blood-protein-signature-invasive-diagnosis.html Tue, 23 Jun 2026 18:20:01 EDT news701450101 "Primary teeth provide a unique timeline of early life," Dr. Synnøve Stokke Jensen at the University of Bergen says. "They preserve information from pregnancy and childhood that cannot be captured retrospectively in other ways. This allows us to investigate environmental exposures during sensitive developmental periods with unprecedented detail." https://medicalxpress.com/news/2026-06-naturally-baby-teeth-key-early.html Tue, 23 Jun 2026 09:20:01 EDT news701423941 Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted with unfamiliar inputs. Suppose you train a neural network to distinguish among African mammals. If you then present it with an image of a South American jaguar—an animal it has never encountered—the model cannot say "unknown." Instead, it may confidently declare the jaguar to be a leopard. https://medicalxpress.com/news/2026-06-framework-ai-trustworthy-cancer-subtyping.html Tue, 23 Jun 2026 05:00:03 EDT news701347110 Mount Sinai researchers have discovered blood RNA biomarkers that offer a promising, minimally invasive approach for earlier diagnosis of Alzheimer's disease, according to findings published in Nature Communications. https://medicalxpress.com/news/2026-06-rna-biomarkers-simple-blood-earlier.html Mon, 22 Jun 2026 13:40:20 EDT news701353239 Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, pathology—the study of disease processes—is essentially based on the time-consuming examination of thin tissue sections, which are stained and then viewed under a microscope. https://medicalxpress.com/news/2026-06-ct-tissue-images-virtually-3d.html Sun, 21 Jun 2026 11:00:01 EDT news701017573 Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies. https://medicalxpress.com/news/2026-06-mass-spectrometry-platform-cancer-drug.html Sat, 20 Jun 2026 13:00:03 EDT news700833735 A common bacterial strain that lives naturally in people's guts can cause a dangerous or deadly infection for some, especially when it becomes multidrug resistant and causes chronic urinary tract infections (UTIs) in elderly women. But the extent of its effect on the broader population and its prevalence in the community were not well known—until now. https://medicalxpress.com/news/2026-06-community-reservoir-drug-resistant-klebsiella.html Thu, 18 Jun 2026 12:00:01 EDT news700998186 A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide because of its ability to resist multiple antifungal drugs and spread rapidly through hospitals and care facilities. https://medicalxpress.com/news/2026-06-therapeutic-dangerous-fungal-infections.html Wed, 17 Jun 2026 14:40:08 EDT news700919881 Human immunodeficiency virus 1 (HIV-1) detection in wastewater offers a novel approach to monitor the virus in communities. Baylor College of Medicine researchers and colleagues at collaborating institutions report in Nature Communications that their method, called hybrid-capture genetic sequencing, allows them to analyze viral genomes in detail and specifically identify viral signals coming from community wastewater. https://medicalxpress.com/news/2026-06-wastewater-hidden-hiv-burden-communities.html Mon, 15 Jun 2026 16:20:13 EDT news700758118 Scientists at King Abdullah University of Science and Technology (KAUST) have developed a new stain-free imaging platform designed to analyze tissue samples more quickly and consistently, supporting future AI-assisted cancer diagnostics. https://medicalxpress.com/news/2026-06-silicon-imaging-cancer-diagnosis-agreement.html Mon, 15 Jun 2026 14:20:01 EDT news700746662 The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high school reunion can tell you, some people age faster than others. https://medicalxpress.com/news/2026-06-blood-biological-ages-disease-years.html Mon, 15 Jun 2026 05:00:05 EDT news700487402 Louse-borne relapsing fever is caused by the spirochete bacterium Borrelia recurrentis, which is transmitted by body lice (not head lice). The disease was first described by Hippocrates (460–370 B.C.). Initial symptoms include a high fever lasting several days, followed by a fever-free interval. Typically, several recurrent episodes of fever follow. The disease can be treated with antibiotics. If left untreated, however, infection with Borrelia recurrentis is fatal in up to 20% of cases—particularly in regions where comprehensive medical care is not available. https://medicalxpress.com/news/2026-06-louse-borne-pathogen-evades-immune.html Wed, 10 Jun 2026 14:20:04 EDT news700316041 A new study by investigators from Mass General Brigham Cancer Institute has found that an ultrasensitive blood test called HPV-DeepSeek could help identify which people with HPV-associated head and neck cancer still had cancer cells in their bodies after surgery and may benefit the most from additional treatments. The results are published in Science Translational Medicine. https://medicalxpress.com/news/2026-06-ultrasensitive-blood-neck-cancer-relapse.html Wed, 10 Jun 2026 14:00:03 EDT news700242001 The integration of AI into digital pathology has the potential to transform cancer diagnostics by enabling scalable, quantitative analysis of tissue specimens. However, widespread deployment of AI-assisted pathology remains challenged by the need for costly imaging infrastructure and the lack of reliable mechanisms to assess prediction confidence. https://medicalxpress.com/news/2026-06-uncertainty-aware-ai-lensfree-holography.html Wed, 10 Jun 2026 13:00:05 EDT news700313461 Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more than 100 molecular subtypes of central nervous system tumors, delivers results within minutes and could accelerate the diagnosis of brain tumors worldwide. The work appears in Nature Cancer. https://medicalxpress.com/news/2026-06-ai-brain-tumors-minutes-weeks.html Wed, 10 Jun 2026 05:00:08 EDT news700235281 Mayo Clinic researchers and collaborators have shown that artificial intelligence (AI) can analyze routine pathology slides to help classify meningiomas, the most common primary brain tumor in adults, and predict a patient's risk of tumor recurrence. https://medicalxpress.com/news/2026-06-ai-reveal-brain-tumor-genetic.html Mon, 08 Jun 2026 12:20:09 EDT news700134542 Infections by hantaviruses are rare but dangerous, killing 30–40% of infected people. When cases occur, public health officials need rapid, detailed information about the virus to identify the strain and its origin, so they can stop others from being exposed to the disease. Whole genome sequencing is an integral part of this work, though the genomes of these viruses are difficult to sequence using existing approaches. https://medicalxpress.com/news/2026-06-hantavirus-sequencing-tool-genomes-hard.html Fri, 05 Jun 2026 14:20:04 EDT news699882301 As we age, our cells acquire cancer-causing mutations, but mutations alone are rarely enough to start a tumor. An environmental trigger, such as exposure to air pollution from sources such as combustion engines, coal burning and cigarette smoke may be needed to tip mutant cells into cancer. Currently, lung cancer screening is offered only to people over a certain age who have previously smoked, missing never-smokers and individuals exposed to high levels of pollutants who may also be at risk of the disease. https://medicalxpress.com/news/2026-06-blood-proteins-lung-cancer-years.html Thu, 04 Jun 2026 16:40:01 EDT news699806042 Sleep loss dulls alertness and coordination, and it can produce effects similar to severe intoxication, making actions like driving incredibly risky. But there's no clinical test for determining when someone is dangerously sleep deprived. Now, researchers report a step toward a non-invasive test for sleep deprivation in the Journal of Proteome Research. In a study of 20 men, they identified molecular differences in saliva after a full night's rest and 24 hours without sleep. https://medicalxpress.com/news/2026-06-deprived.html Wed, 03 Jun 2026 17:50:02 EDT news699725402 An international research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) has developed HERRO, an artificial intelligence (AI) tool that could make it easier and more cost-effective to produce complete, high-quality genome assemblies. https://medicalxpress.com/news/2026-06-ai-tool-scales-genome-advances.html Wed, 03 Jun 2026 15:40:03 EDT news699716941