https://medicalxpress.com/cancer-news/ en-us Latest medical news and research in Oncology A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. The results, published in Molecular Therapy Oncology, present the first preclinical evidence showing the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer. https://medicalxpress.com/news/2026-06-anticancer-vaccine-early-success-neuroblastoma.html Thu, 18 Jun 2026 19:20:01 EDT news701014621 Researchers at Columbia University have identified a switch that turns on the rapid production of blood cells in emergency situations, a finding that could help researchers uncover new treatments for aging and some of the most difficult-to-treat blood cancers. https://medicalxpress.com/news/2026-06-body-emergency-blood-factory-aging.html Thu, 18 Jun 2026 18:20:01 EDT news701014124 Immunotherapies are a promising approach in the fight against cancer. Researchers at the Technical University of Munich (TUM) have developed a lab-on-a-chip system called CellTrap. It makes it possible to observe the interactions between immune cells and cancer cells at the single-cell level. The method is intended to reveal fundamental processes in cancer immunology and answer key questions. The technology is described in the journal RSC Advances. https://medicalxpress.com/news/2026-06-lab-chip-platform-immune-cells.html Thu, 18 Jun 2026 17:40:03 EDT news701013751 Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have identified a molecule on the surface of cells that could be a promising therapeutic target against cancer. This molecule plays an important role in tumor progression by regulating cellular behavior. The research is published in the journal Cytotechnology. https://medicalxpress.com/news/2026-06-molecule-cancer-cell-surfaces-therapies.html Thu, 18 Jun 2026 17:10:01 EDT news701019841 The HPV vaccine for cervical cancer has reduced the risk of dying from the disease before age 30 in England to almost zero, the first study of its kind showed Thursday. https://medicalxpress.com/news/2026-06-vaccine-england-youngest-women-dying.html Thu, 18 Jun 2026 17:00:05 EDT news701013013 Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in development of the disease. The work provides insight into the initial phases of the disease and may eventually lead to tailored monitoring techniques that improve patient outcomes. https://medicalxpress.com/news/2026-06-rare-genetic-mutation-doesnt-result.html Thu, 18 Jun 2026 15:00:03 EDT news701010808 Physicians and researchers at the Netherlands Cancer Institute have developed an AI model that outperforms physicians in evaluating treatment response in pleural mesothelioma. Far more accurate than the current international standard criteria (RECIST), the model provides patients with greater certainty and tailored treatments. It changes how physicians assess tumors and could accelerate the development of new treatments by making clinical trials more reliable and efficient. https://medicalxpress.com/news/2026-06-ai-heavyweight-tumor-mesothelioma-patients.html Wed, 17 Jun 2026 18:30:04 EDT news700900981 University of Guelph research published in the journal publication Blood has uncovered a surprising weakness in acute myeloid leukemia (AML) that a compound in a common skin care ingredient may be able to target. https://medicalxpress.com/news/2026-06-inhibiting-high-leukemia-abcd1-protein.html Wed, 17 Jun 2026 18:00:06 EDT news700931546 Scientists know that colorectal cancer cells require large amounts of iron and that as cancer becomes more aggressive, the cells have even higher amounts of iron. Normal cells with high levels of iron would undergo a type of iron-related cell death called ferroptosis. But in cancer cells, the iron continues to accumulate well beyond normal levels without succumbing to expected cell death processes. https://medicalxpress.com/news/2026-06-colorectal-tumors-mitochondrial-complex-ii.html Wed, 17 Jun 2026 16:40:10 EDT news700931495 Researchers at the Medical University of Vienna have described a mechanism in metastatic colorectal cancer that has received little attention to date: A key target of existing therapies, the so-called epidermal growth factor receptor (EGFR), is likely to affect more than just the cancer cells themselves. The study shows that EGFR also influences certain immune cells in the tumor microenvironment—and thereby helps determine how effectively the body's own defenses can combat the tumor. The findings have recently been published in the journal Cell Death & Differentiation. https://medicalxpress.com/news/2026-06-colorectal-cancer-reveals-mechanism-therapy.html Wed, 17 Jun 2026 13:40:10 EDT news700918921 Researchers from National Taiwan University (NTU) and National Taiwan University Hospital (NTUH) have identified a promising way to reinvigorate the body's cancer-fighting immune cells by rewiring their metabolism, revealing a potential new strategy for cancer immunotherapy. https://medicalxpress.com/news/2026-06-rewired-metabolism-revive-exhausted-immune.html Wed, 17 Jun 2026 13:00:12 EDT news700916701 Researchers at the State University of Campinas (UNICAMP) in São Paulo, Brazil, have identified a new biomarker that may help determine the prognosis for patients with gastric cancer, the fifth most common type of cancer worldwide. The team identified a variable that combines data on the radiodensity of visceral fat and muscle by analyzing images from computed tomography (CT) scans, a routine examination for these patients. This variable can distinguish those at higher risk of unfavorable disease progression. https://medicalxpress.com/news/2026-06-marker-tomography-refine-gastric-cancer.html Wed, 17 Jun 2026 11:40:05 EDT news700905601 A new study led by researchers at The University of Texas MD Anderson Cancer Center has uncovered a previously unknown connection between nucleic acid structures called R-loops and age-related inflammation—or inflammaging—that could herald new intervention options for chronic inflammation and the subsequent health conditions. https://medicalxpress.com/news/2026-06-age-inflammation-treatment-pathway.html Wed, 17 Jun 2026 09:40:05 EDT news700903202 Vapes or e-cigarettes were marketed as a safer, smokeless alternative to traditional cigarettes and even promoted as a tool to help smokers quit. Their fruity flavors and sleek designs further reinforced the perception that they were a less harmful substitute for conventional tobacco products. While quitting smoking is known to reduce cancer risk over time, growing evidence suggests that switching to e-cigarettes may not be as harmless. https://medicalxpress.com/news/2026-06-vaping-people-ditch-cigarettes-lung.html Wed, 17 Jun 2026 08:40:03 EDT news700818348 Duke-NUS scientists have discovered that aging muscle may contribute to cancer growth by releasing fewer extracellular vesicles, tiny particles that cells use to communicate with one another. Their study also found that the composition of these particles changes with age, weakening protective signals that help suppress tumor development. https://medicalxpress.com/news/2026-06-scientists-uncover-physical-older-adults.html Wed, 17 Jun 2026 07:40:01 EDT news700897741 A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core genetic changes that can be traced back to a common ancestral cell, providing a single-cell view of how tumors adapt, survive and diversify. Understanding this helps explain why some cancer cells manage to survive treatment, paving the way for more tailored diagnostic and therapeutic strategies. https://medicalxpress.com/news/2026-06-cancers-cancer-cell-evolve-early.html Tue, 16 Jun 2026 18:20:07 EDT news700846861 A study led by Georgia Institute of Technology's Associate Professor Costas Arvanitis takes a major step toward safer and more effective treatment and diagnosis of brain diseases. His team's research, published in Advanced Science, shows how combining artificial intelligence (AI) with focused ultrasound can safely deliver therapies and improve diagnostic interventions to the brain. https://medicalxpress.com/news/2026-06-ai-ultrasound-bloodbrain-barrier-procedures.html Tue, 16 Jun 2026 17:00:06 EDT news700845182 Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression. https://medicalxpress.com/news/2026-06-hidden-pim1-pathway-prostate-cancer.html Tue, 16 Jun 2026 15:20:03 EDT news700838188 Researchers at the University of Cologne's Center for Molecular Medicine Cologne (CMMC) have discovered a previously unknown mechanism that makes most pancreatic cancer cells susceptible to a form of programmed cell death. The team, led by Professor Dr. Silvia von Karstedt, showed that cancer cells with mutations in the KRAS gene develop a vulnerability that can be used to eliminate tumor cells in preclinical models. The findings open up new perspectives for treating pancreatic cancer. The study "Oncogenic KRAS-Driven type I Interferon Signalling Primes Pancreatic Cancer for Necroptosis" was published in the journal Nature Communications. https://medicalxpress.com/news/2026-06-pancreatic-cancer-strategy-kras-mutant.html Tue, 16 Jun 2026 15:00:08 EDT news700834921