https://medicalxpress.com/medications-news/ en-us Latest medical news and research in Clinical pharmacology Michigan State University researchers have identified how ovarian cancer cells become resistant to chemotherapy and discovered a protein that, when blocked, can restore the drug's effectiveness. https://medicalxpress.com/news/2026-06-scientists-uncover-ovarian-cancer-resists.html Sun, 28 Jun 2026 14:00:04 EDT news701600202 Researchers at the Nuffield Department of Primary Care Health Sciences, University of Oxford, have developed a new calculator that estimates a person's risk of developing serious muscle disorders from statins. The tool could help patients and clinicians make more informed decisions about using these widely prescribed medications to prevent heart attacks and strokes. https://medicalxpress.com/news/2026-06-statin-muscle-side-effects-rare.html Fri, 26 Jun 2026 12:40:01 EDT news701691181 An international research team led by investigators in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai has developed the first fully human monoclonal antibody cocktail shown to provide complete protection against lethal Nipah and Hendra virus infection. The protection was seen even when treatment was given after infection had begun. https://medicalxpress.com/news/2026-06-dual-human-antibodies-lethal-nipah.html Fri, 26 Jun 2026 09:40:03 EDT news701683934 The quest to prolong life has gone on for as long as human existence itself, from the mythical Fountain of Youth to quick-fix fads like intermittent fasting, supplements and injections. But if you take a look in your medicine cabinet, you may unwittingly come across a drug that holds a key to longevity. Could that nasal spray for your stuffy nose be repurposed to reverse one or more of the processes of aging? https://medicalxpress.com/news/2026-06-drugs-repurposed-longevity-network-aging.html Fri, 26 Jun 2026 09:20:04 EDT news701683864 Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively. By packaging a chemotherapy drug and an RNA molecule in a tiny lipid carrier, the team boosted an immune response that slowed tumor growth and enhanced the effects of immunotherapy. https://medicalxpress.com/news/2026-06-nanotech-platform-combining-paclitaxel-sirna.html Thu, 25 Jun 2026 16:40:09 EDT news701621568 The ongoing evolution of SARS-CoV-2, particularly the rapid emergence of the omicron variant and its sublineages, has weakened the effectiveness of existing vaccines and antiviral drugs, underscoring the potential risk of future coronavirus pandemics. In response, a joint research team from the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the School of Pharmaceutical Sciences of Tsinghua University has developed MB-32, a novel broad-spectrum small-molecule antiviral drug candidate. https://medicalxpress.com/news/2026-06-small-molecule-antiviral-drug-ace2.html Thu, 25 Jun 2026 16:20:02 EDT news701620024 An early clinical study shows that a new oral drug is safe and well tolerated in patients with chronic heart failure. The study, led by researchers at Karolinska Institutet, has been published in The Lancet. https://medicalxpress.com/news/2026-06-oral-heart-failure-drug-safe.html Thu, 25 Jun 2026 14:20:07 EDT news701609295 A Monash University-led study has found that an unusual pairing of two commonly used antibiotics can kill and stop the spread of resistance in a highly drug-resistant bacterium, Pseudomonas aeruginosa, which can cause life-threatening bloodstream infections, pneumonia and meningitis. https://medicalxpress.com/news/2026-06-combination-therapy-global-antibiotic-resistance.html Thu, 25 Jun 2026 13:00:06 EDT news701609179 Between 50% and 100% of people in countries with poor access to clean water are infected with a bacterium called Helicobacter pylori. This bacterium is a leading cause of stomach ulcers, and it can even cause gastric cancer. https://medicalxpress.com/news/2026-06-unfolding-stomach-capsule-ulcer-bacteria.html Thu, 25 Jun 2026 09:20:01 EDT news701596682 Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. One of the most important cancer-related signaling molecules is the Kirsten rat sarcoma viral oncogene homologue (KRAS), which functions like an on/off switch for cell growth. https://medicalxpress.com/news/2026-06-cancer-cells-survive-kras-inhibition.html Thu, 25 Jun 2026 09:00:01 EDT news701596165 "Peacemaker" immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science. https://medicalxpress.com/news/2026-06-peacemakers-immune-term-disease-remission.html Thu, 25 Jun 2026 05:00:01 EDT news701519221 A new strategy for delivering GLP-1 drugs to patients with obesity or who were overweight resulted in up to a 12% reduction in body weight after 36 weeks, according to a randomized phase II clinical trial published in Nature Medicine. https://medicalxpress.com/news/2026-06-oral-glp-drug-weight-loss.html Wed, 24 Jun 2026 17:00:03 EDT news701531914 Cholesterol-related heart disease remains the leading cause of death worldwide, and while doctors have more tools than ever to treat it, many patients still can't achieve safe cholesterol levels or can't tolerate the side effects of available medications. https://medicalxpress.com/news/2026-06-high-cholesterol-dismantles-liver-defenses.html Wed, 24 Jun 2026 11:00:05 EDT news701431741 Pancreatic cancer is one of the deadliest cancers and the third-leading cause of cancer-related death in the United States. While scientists continue searching for new therapies, advances can also come from understanding how existing drugs work. By uncovering the underlying biology, researchers can identify new ways to use existing drugs, improve their effectiveness and overcome barriers that have limited their clinical impact. https://medicalxpress.com/news/2026-06-foundational-therapeutic-strategies-emerging-cancer.html Tue, 23 Jun 2026 16:40:01 EDT news701446036 Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye. Although scientists know some of the structural changes that ensue as this damage progresses, less is understood about the molecular signals that shape how the retina copes with disease. https://medicalxpress.com/news/2026-06-erucamide-molecule-eye-response-retinal.html Mon, 22 Jun 2026 19:40:06 EDT news701360308 Our body loves the state of homeostasis, where everything is in perfect equilibrium, from temperature to pH levels to fluid balance. As soon as the body's core temperature drops below 95°F (35°C) and stays there for a long time, the heart, nervous system and other organs start to function poorly, which makes hypothermia extremely dangerous when not dealt with immediately. It is a medical emergency that can result in loss of consciousness or death. https://medicalxpress.com/news/2026-06-hibernation-cooling-brain.html Fri, 19 Jun 2026 15:20:02 EDT news701082772