https://medicalxpress.com/medications-news/ en-us Latest medical news and research in Clinical pharmacology A recent paper in Nature Biotechnology examines problems and solutions for antibody-based therapies for solid pancreatic cancers and tumors of the head and neck. https://medicalxpress.com/news/2026-06-cell-platform-tracks-antibody-drug.html Wed, 03 Jun 2026 05:00:02 EDT news699614161 The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. Results from a study in the Journal of Internal Medicine suggest that this may prompt a clinician to run tests to uncover an asymptomatic bladder tumor. https://medicalxpress.com/news/2026-06-aspirin-unmask-silent-bladder-cancer.html Wed, 03 Jun 2026 03:10:01 EDT news699611881 Millions of Americans are currently taking GLP-1 medications such as Ozempic or Wegovy for weight loss. But along with the fat, many are quietly losing something else: muscle. Unlike fat, muscle doesn't return quickly, and muscle loss can have deleterious effects on strength, mobility, and overall health. https://medicalxpress.com/news/2026-06-drug-muscle-glp-weight-loss.html Tue, 02 Jun 2026 18:20:04 EDT news699634921 The Global Hypertension Report by the World Health Organization (WHO) revealed that 1.4 billion people were living with hypertension in 2024. Yet, only a little over one in five of those diagnosed have it under control, whether through medication or by managing modifiable health risks. Fear of side effects is a major barrier to effective blood pressure control, often discouraging people from starting medication, accepting higher doses, or staying on treatment for the long term. https://medicalxpress.com/news/2026-06-high-blood-pressure-drug-combinations.html Tue, 02 Jun 2026 10:00:05 EDT news699612171 Three-quarters of people who respond well to the newest types of biologics for psoriasis can safely reduce their dosage, often even by half. These medications then work just as effectively, according to a study led by Radboud University Medical Center and Ghent University Hospital. The finding results in fewer injections and saves up to €8,500 (~$9,900) per patient per year. The study is published in The Lancet Regional Health—Europe. https://medicalxpress.com/news/2026-06-medicines-dosage-stable-psoriasis.html Mon, 01 Jun 2026 19:30:01 EDT news699521941 FDA-approved carbon copies of brand-name drugs with expired patents—over the last 30 years, these generic drugs have saved trillions of dollars for hundreds of millions of people. https://medicalxpress.com/news/2026-06-global-access-glp-drugs.html Mon, 01 Jun 2026 13:40:05 EDT news699535682 Patients in London have received a pioneering new gene editing therapy that lowers "bad" cholesterol after a single infusion, as part of a study involving UCL scientists. https://medicalxpress.com/news/2026-05-gene-treatment-lowers-bad-cholesterol.html Sun, 31 May 2026 11:00:01 EDT news699200363 New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining asthma control and improving key clinical outcomes. The findings were published in The Lancet Respiratory Medicine. https://medicalxpress.com/news/2026-05-tezepelumab-severe-asthma-patients-oral.html Sat, 30 May 2026 14:00:01 EDT news699274281 Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant to a specific form of cell death known as ferroptosis.⮐ https://medicalxpress.com/news/2026-05-inhibitor-outcome-effect-reshape-ferroptosis.html Sat, 30 May 2026 06:08:06 EDT news699340017 A new study by researchers at the University of Sydney has shown that taking cannabidiol (CBD) can significantly reduce chronic neuropathic pain in those suffering from it. The findings of the randomized placebo-controlled trial, published in eClinicalMedicine, demonstrated that taking CBD over a six-week period reduced pain by approximately 14%, compared to 6.5% from the placebo. https://medicalxpress.com/news/2026-05-cannabidiol-significantly-chronic-pain-nerve.html Fri, 29 May 2026 12:00:02 EDT news699268613 A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. https://medicalxpress.com/news/2026-05-simulation-uncovers-tuberculosis-drug-candidates.html Fri, 29 May 2026 11:20:05 EDT news699269760 Scientists at Université de Montréal have figured out how metformin—a common drug that's used to treat type-2 diabetes and that may cut the risk of developing cancer and even help humans and other mammals live longer—actually works. https://medicalxpress.com/news/2026-05-metformin-diabetes-reshape-aging-cancer.html Fri, 29 May 2026 09:20:08 EDT news699263013 The targeted therapy sunvozertinib was more effective than standard platinum-based chemotherapy as a first-line treatment for patients with advanced non-small cell lung cancer (NSCLC) driven by EGFR exon 20 insertion mutations (EGFR exon20ins), according to new research from The University of Texas MD Anderson Cancer Center. https://medicalxpress.com/news/2026-05-drug-outperforms-chemotherapy-patients-hard.html Fri, 29 May 2026 09:00:05 EDT news699262944 A dangerous sedative called medetomidine has been quietly spreading through New York's illicit drug supply. A new analysis shows how, over several years of careful tracking and coordination, public health agencies in New York State executed a data-driven response to alert the public, make health practitioners aware of the emergent substance, distribute test strips and ultimately save lives. https://medicalxpress.com/news/2026-05-dangerous-drug-adulterant-health-response.html Thu, 28 May 2026 13:42:24 EDT news699194463 Evening coffee has sparked controversy for years. Some people fall asleep without difficulty, while others toss and turn for half the night. However, a growing body of research suggests the question of whether coffee makes it harder to fall asleep may be too simplistic. What appears to matter far more is what happens in the brain during sleep. https://medicalxpress.com/news/2026-05-caffeine-sabotage-deep-hours.html Wed, 27 May 2026 14:40:04 EDT news699101523