https://medicalxpress.com/orthopedics-news/ en-us Latest medical news and research in Orthopaedics As professional baseball sees another high-profile elbow injury with Toronto Blue Jays right-hander José Berríos having undergone ulnar collateral ligament (UCL) surgery, new research from the University of Waterloo suggests many pitchers may be able to reduce stress on their elbows without sacrificing velocity. https://medicalxpress.com/news/2026-05-smarter-softer-baseball-pitchers-elbows.html Wed, 27 May 2026 13:20:01 EDT news699100141 Researchers have developed a novel mouse model that replicates severe geleophysic dysplasia, including short stature, heart valve alterations, and early lethality—characteristics of this rare disease. The findings from the study in The American Journal of Pathology provide a basis for the identification of molecular mechanisms underlying geleophysic dysplasia, which can then be targeted for therapeutic purposes. https://medicalxpress.com/news/2026-05-mouse-recreates-severe-geleophysic-dysplasia.html Mon, 18 May 2026 18:00:06 EDT news698340179 Eyes, the high-resolution biological devices that help us visualize the outside world, are now being used as a portal to assess our internal health. Scientists have found that a closer evaluation of how one's retina is aging can provide crucial hints about bone health, especially in conditions such as osteoporosis, which makes bones weaker and more prone to fractures. https://medicalxpress.com/news/2026-05-written-eye-retina-biological-age.html Mon, 18 May 2026 12:00:09 EDT news698322087 Scientists' discovery of a molecular "switch" that activates an energy-burning pathway in mice has the potential to lead to new treatments for bone disease. The study, published in Nature, sheds new light on brown fat. Unlike white fat, which stores energy, brown fat cells burn calories, producing heat as a byproduct. For years, it was believed this process relied on a single pathway. More recently, researchers discovered a parallel pathway, but how it became activated had remained a mystery. https://medicalxpress.com/news/2026-05-discovery-fat-advances-bone-disease.html Sat, 16 May 2026 10:00:03 EDT news697733631 Researchers at Tampere University, Finland, have developed a groundbreaking 3D-printed ceramic implant material that closely mimics real human bone. The findings advance the development of personalized bone regeneration and may lead to more effective and accessible treatments for bone defects. https://medicalxpress.com/news/2026-05-3d-ceramic-implants-mimic-human.html Fri, 15 May 2026 11:20:08 EDT news698061302 Increasing bone density in patients with a rare genetic condition that causes bones to break easily does not prevent fractures, a large clinical trial has found. Patients with brittle bone disease who were given treatments to boost their bone density experienced a similar number of fractures as those who received standard care. https://medicalxpress.com/news/2026-05-drug-trial-treatment-shift-brittle.html Thu, 14 May 2026 11:00:05 EDT news697909321 Partial meniscectomy does not improve patient symptoms or function, reveals a 10-year follow-up of the FIDELITY, a placebo-surgery controlled trial published in the New England Journal of Medicine. https://medicalxpress.com/news/2026-04-world-common-knee-surgeries.html Wed, 29 Apr 2026 17:00:06 EDT news696700201 Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells. Despite its physiological importance, the developmental mechanism by which this soft tissue is formed within the rigid confines of hard bone has remained largely unknown. https://medicalxpress.com/news/2026-04-bones-marrow-newly-cells-reappear.html Tue, 28 Apr 2026 17:30:01 EDT news696614941 Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have developed a mouse model for the disease and were thus able to show that a disruption in cellular recycling—known technically as autophagy—is the primary trigger for the disease. Their findings have been published in Nature Communications. https://medicalxpress.com/news/2026-04-impaired-cell-recycling-muscle-weakness.html Fri, 24 Apr 2026 15:00:03 EDT news696254881 The University of Tasmania's Menzies Institute for Medical Research has found that the commonly prescribed medication, Diacerein, does not improve knee osteoarthritis symptoms, following a national study. Diacerein, a medication derived from plants such as rhubarb and aloe vera, has long been recognized for its anti-inflammatory properties and is commonly used to treat osteoarthritis in Europe and Asia. https://medicalxpress.com/news/2026-04-common-drug-ease-knee-osteoarthritis.html Tue, 21 Apr 2026 19:20:01 EDT news696004081 Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science Tokyo. They analyzed mouse embryonic forelimb cells across different developmental stages using single-cell-level gene expression analysis and a state-of-the-art technique to detect Sox9's DNA binding sites. The findings lay the foundation for future research on skeletal diseases and regenerative medicine. https://medicalxpress.com/news/2026-04-key-regulatory-protein-cartilage-formation.html Tue, 21 Apr 2026 17:30:03 EDT news696008461 Broken wrists are among the most common injuries in children, accounting for about half of children's fractures. Severely displaced distal radial fractures, where the bones move out of place, are often routinely treated with surgery. However—unlike adults—children have a remarkable ability to straighten broken bones, in a process called remodeling. Researchers questioned whether a plaster cast would achieve the same long-term result without exposing children to the risks of an operation. https://medicalxpress.com/news/2026-04-large-trial-bone-superpower-children.html Fri, 17 Apr 2026 04:00:01 EDT news695554804 Researchers found that a diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of calorie or fat intake, physical activity or sociodemographic factors in a population at risk for knee osteoarthritis. Results of the study were published in Radiology. Higher amounts of intramuscular fat in the thigh could potentially increase the risk for knee osteoarthritis. https://medicalxpress.com/news/2026-04-people-consume-ultra-foods-worse.html Tue, 14 Apr 2026 10:00:01 EDT news695293502 Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bone quality deficits specifically in female mice, through a mechanism that is invisible to standard imaging and can emerge as early as midlife. The findings, published in Advanced Science, reveal an unexpected biological link between Alzheimer's risk and skeletal health, and identify a new molecular pathway that could one day inform earlier diagnosis of cognitive decline or guide treatment for bone quality loss in women who carry the APOE4 gene. https://medicalxpress.com/news/2026-04-apoe4-alzheimer-gene-silently-undermines.html Mon, 13 Apr 2026 18:20:02 EDT news695318042 Good news: Scientists may be closer to a new way to treat arthritis. https://medicalxpress.com/news/2026-04-scientists-ways-regrow-joints-arthritis.html Tue, 07 Apr 2026 16:00:01 EDT news694783635