https://medicalxpress.com/orthopedics-news/ en-us Latest medical news and research in Orthopaedics The largest and longest clinical trial of its kind has found that resurfacing the kneecap during total knee replacement is likely to be the most cost-effective approach for patients and health care systems over the long term. Researchers from the University of Oxford and the University of Aberdeen followed more than 1,700 patients for 20 years as part of the KAT (Knee Arthroplasty Trial) study, making it the longest randomized controlled trial ever conducted in knee orthopedics. https://medicalxpress.com/news/2026-06-kneecap-resurfacing-patients-health.html Wed, 17 Jun 2026 18:30:05 EDT news700906032 Embolization of abnormal blood vessels using rapidly resorbable gelatin-based microspheres is safe and provides significant, lasting pain relief and functional improvement for patients with osteoarthritis-related knee pain, according to a new study published in Radiology. https://medicalxpress.com/news/2026-06-nonsurgical-procedure-relief-knee-pain.html Tue, 16 Jun 2026 10:00:03 EDT news700735021 Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, sometimes decades, inside the human body. And modern hip and knee implants exceed expectations, providing long service time and significantly improved quality of life for the vast majority of patients. But durability inside biology, especially the human body, is never static once a foreign material is introduced. It responds continuously, at every scale. https://medicalxpress.com/news/2026-06-joints-corrosion-reshape-hip-knee.html Mon, 15 Jun 2026 17:10:03 EDT news700759501 For patients suffering from traumatic injuries that leave behind "volumetric" gaps—where significant bone and blood vessels are lost—the clock is always ticking. Without a nearby blood supply, cells in the center of a large injury cannot survive, often leading to permanent tissue loss or failed grafts. https://medicalxpress.com/news/2026-06-natural-protein-scaffold-bone-blood.html Thu, 11 Jun 2026 16:40:04 EDT news700413241 An international research team has identified dozens of new genetic risk factors linked to lumbar spinal stenosis, a common degenerative condition of the lower spine. The study, led by researchers at the University of Oulu, provides new insight into the biological mechanisms behind one of the most frequent causes of mobility problems in older adults. The work was published in the journal Nature Communications. https://medicalxpress.com/news/2026-06-nerve-pain-genetic-clues-reshape.html Tue, 09 Jun 2026 19:00:01 EDT news700243022 For millions of people living with osteoarthritis, daily life can involve a frustrating cycle of pain and stiffness. While current treatments like over-the-counter medications or steroid injections can temporarily dull the ache, they do not stop the joint from deteriorating. A Yale study published in the journal Bioactive Materials found that the medication lacosamide acts as a highly effective, dual-purpose treatment that relieves joint pain and reverses cartilage damage in osteoarthritis, especially when a specialized hydrogel delivers the drug directly into the joint. https://medicalxpress.com/news/2026-06-hydrogel-relieves-osteoarthritis-pain-cartilage.html Wed, 03 Jun 2026 12:40:02 EDT news699706023 As professional baseball sees another high-profile elbow injury with Toronto Blue Jays right-hander José Berríos having undergone ulnar collateral ligament (UCL) surgery, new research from the University of Waterloo suggests many pitchers may be able to reduce stress on their elbows without sacrificing velocity. https://medicalxpress.com/news/2026-05-smarter-softer-baseball-pitchers-elbows.html Wed, 27 May 2026 13:20:01 EDT news699100141 Researchers have developed a novel mouse model that replicates severe geleophysic dysplasia, including short stature, heart valve alterations, and early lethality—characteristics of this rare disease. The findings from the study in The American Journal of Pathology provide a basis for the identification of molecular mechanisms underlying geleophysic dysplasia, which can then be targeted for therapeutic purposes. https://medicalxpress.com/news/2026-05-mouse-recreates-severe-geleophysic-dysplasia.html Mon, 18 May 2026 18:00:06 EDT news698340179 Eyes, the high-resolution biological devices that help us visualize the outside world, are now being used as a portal to assess our internal health. Scientists have found that a closer evaluation of how one's retina is aging can provide crucial hints about bone health, especially in conditions such as osteoporosis, which makes bones weaker and more prone to fractures. https://medicalxpress.com/news/2026-05-written-eye-retina-biological-age.html Mon, 18 May 2026 12:00:09 EDT news698322087 Scientists' discovery of a molecular "switch" that activates an energy-burning pathway in mice has the potential to lead to new treatments for bone disease. The study, published in Nature, sheds new light on brown fat. Unlike white fat, which stores energy, brown fat cells burn calories, producing heat as a byproduct. For years, it was believed this process relied on a single pathway. More recently, researchers discovered a parallel pathway, but how it became activated had remained a mystery. https://medicalxpress.com/news/2026-05-discovery-fat-advances-bone-disease.html Sat, 16 May 2026 10:00:03 EDT news697733631 Researchers at Tampere University, Finland, have developed a groundbreaking 3D-printed ceramic implant material that closely mimics real human bone. The findings advance the development of personalized bone regeneration and may lead to more effective and accessible treatments for bone defects. https://medicalxpress.com/news/2026-05-3d-ceramic-implants-mimic-human.html Fri, 15 May 2026 11:20:08 EDT news698061302 Increasing bone density in patients with a rare genetic condition that causes bones to break easily does not prevent fractures, a large clinical trial has found. Patients with brittle bone disease who were given treatments to boost their bone density experienced a similar number of fractures as those who received standard care. https://medicalxpress.com/news/2026-05-drug-trial-treatment-shift-brittle.html Thu, 14 May 2026 11:00:05 EDT news697909321 Partial meniscectomy does not improve patient symptoms or function, reveals a 10-year follow-up of the FIDELITY, a placebo-surgery controlled trial published in the New England Journal of Medicine. https://medicalxpress.com/news/2026-04-world-common-knee-surgeries.html Wed, 29 Apr 2026 17:00:06 EDT news696700201 Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells. Despite its physiological importance, the developmental mechanism by which this soft tissue is formed within the rigid confines of hard bone has remained largely unknown. https://medicalxpress.com/news/2026-04-bones-marrow-newly-cells-reappear.html Tue, 28 Apr 2026 17:30:01 EDT news696614941 Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have developed a mouse model for the disease and were thus able to show that a disruption in cellular recycling—known technically as autophagy—is the primary trigger for the disease. Their findings have been published in Nature Communications. https://medicalxpress.com/news/2026-04-impaired-cell-recycling-muscle-weakness.html Fri, 24 Apr 2026 15:00:03 EDT news696254881 Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science Tokyo. They analyzed mouse embryonic forelimb cells across different developmental stages using single-cell-level gene expression analysis and a state-of-the-art technique to detect Sox9's DNA binding sites. The findings lay the foundation for future research on skeletal diseases and regenerative medicine. https://medicalxpress.com/news/2026-04-key-regulatory-protein-cartilage-formation.html Tue, 21 Apr 2026 17:30:03 EDT news696008461