https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology A new study revealed molecular features linked to more aggressive prostate cancer in a subset of patients who had been classified as low risk, highlighting biological differences that may not be apparent from clinical measures alone. The results could lead to new therapeutic strategies. https://medicalxpress.com/news/2026-10-prostate-tumors-reveal-molecular-linked.html Wed, 07 Oct 2026 16:40:06 EDT news710605686 Researchers at Fred Hutch Cancer Center have identified a previously overlooked molecular regulator that helps determine whether prostate tumors remain sensitive to treatment or evolve into a more aggressive, drug-resistant form of the disease. https://medicalxpress.com/news/2026-10-key-driver-aggressive-prostate-cancer.html Wed, 07 Oct 2026 11:00:02 EDT news710522401 A simple urine test devised by researchers at Stanford Medicine and the VA Palo Alto Health Care System can diagnose bladder cancer more accurately than current standard methods. The test also allows physicians not only to assess the cancer's response to treatment but also to predict whether immunotherapy or chemotherapy is likely to be most effective for each patient. https://medicalxpress.com/news/2026-10-rna-urine-outperforms-standard-bladder.html Fri, 02 Oct 2026 05:00:01 EDT news710067602 A genetic vulnerability in clear cell renal cell carcinoma, the most aggressive type of kidney cancer, may lend itself to a combination treatment strategy that causes the cancer cells to self-destruct, according to recent research published in the Proceedings of the National Academy of Sciences. https://medicalxpress.com/news/2026-09-combination-therapy-emerges-treatment-aggressive.html Wed, 30 Sep 2026 17:40:01 EDT news710000703 Urinary tract infections, or UTIs, are among the most common bacterial infections and are caused mostly by the uropathogenic bacterium Escherichia coli. But even after antibiotic treatment, many patients experience another UTI. https://medicalxpress.com/news/2026-09-hidden-coli-survive-bladder-cells.html Fri, 25 Sep 2026 14:00:01 EDT news709545120 A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease. Published in Oncogene, the study found high levels of neuromedin U (NMU), a neurotransmitter, in prostate cells during the earliest phase of NEPC formation. https://medicalxpress.com/news/2026-09-neurotransmitter-aggressive-prostate-cancer-immune.html Fri, 25 Sep 2026 11:40:23 EDT news709553101 Chronic stress may contribute to the pain and urinary symptoms experienced by people with interstitial cystitis/bladder pain syndrome (IC/BPS) by triggering changes in the bladder and nervous system, according to a preclinical study by Weill Cornell Medicine investigators. https://medicalxpress.com/news/2026-09-ease-stress-bladder-pain-frequent.html Wed, 23 Sep 2026 09:20:03 EDT news709373401 Using prostate MRI before a biopsy is a real advance in prostate cancer diagnosis. Multiple randomized trials have shown that imaging the prostate first and then targeting suspicious lesions finds more of the aggressive cancers that matter. As a result, guidelines have progressively strengthened their recommendations for MRI. https://medicalxpress.com/news/2026-09-mri-prostate-biopsies-sharply-hospitals.html Sun, 20 Sep 2026 15:20:01 EDT news708960663 An elevated PSA level in the blood may indicate prostate cancer but does not allow for a definitive diagnosis. Where there is a corresponding suspicion, a tissue sample is usually taken from the prostate. A study by the Medical University of Vienna now shows that a specialized form of imaging—known as PSMA-PET/CT—could provide important additional information even before such a biopsy is carried out. https://medicalxpress.com/news/2026-09-prostate-cancer-specialized-imaging-unnecessary.html Tue, 15 Sep 2026 17:40:07 EDT news708704822 Combining the targeted therapy olaparib with an additional immunotherapy may improve immune response in a subgroup of patients with metastatic castration-resistant prostate cancer who responded poorly to initial treatment, according to a Northwestern Medicine study published in The Journal of Clinical Investigation. https://medicalxpress.com/news/2026-09-combination-therapy-immune-response-advanced.html Thu, 10 Sep 2026 15:00:01 EDT news708262756 Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with it for years while it progresses aggressively in others. https://medicalxpress.com/news/2026-09-dna-signatures-reveal-prostate-cancers.html Wed, 09 Sep 2026 11:00:20 EDT news708169081 Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects. Now, scientists have identified an unexpected participant in androgen chemistry: a bacterium from the human urinary tract that can convert the steroid precursor DHEA into testosterone under laboratory conditions. https://medicalxpress.com/news/2026-09-bacteria-testosterone-prostate-cancer.html Mon, 07 Sep 2026 09:00:04 EDT news707989741 A lab-grown micro bladder may explain why urinary tract infections (UTIs) return so frequently, according to a study led by researchers at UCL, the University of Oxford and the University of Leicester. https://medicalxpress.com/news/2026-09-micro-bladder-clues-recurrent-utis.html Fri, 04 Sep 2026 05:00:01 EDT news707653211