https://medicalxpress.com/cancer-news/ en-us Latest medical news and research in Oncology A recent paper in Nature Biotechnology examines problems and solutions for antibody-based therapies for solid pancreatic cancers and tumors of the head and neck. https://medicalxpress.com/news/2026-06-cell-platform-tracks-antibody-drug.html Wed, 03 Jun 2026 05:00:02 EDT news699614161 Cancer researchers highlighted several treatment breakthroughs during their annual summit in Chicago that concluded Tuesday, including preliminary but encouraging data on potential benefits of weight loss medications. https://medicalxpress.com/news/2026-06-cancer-advances-emerging-treatments.html Wed, 03 Jun 2026 04:04:34 EDT news699678172 The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. Results from a study in the Journal of Internal Medicine suggest that this may prompt a clinician to run tests to uncover an asymptomatic bladder tumor. https://medicalxpress.com/news/2026-06-aspirin-unmask-silent-bladder-cancer.html Wed, 03 Jun 2026 03:10:01 EDT news699611881 A smartphone app can help individuals with advanced cancer deal with symptoms and maintain their quality of life, according to new research. https://medicalxpress.com/news/2026-06-smartphone-app-advanced-cancer-quality.html Tue, 02 Jun 2026 23:40:01 EDT news699624208 A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Over the years, many novel ADC therapies have been approved for treating various types of cancers. https://medicalxpress.com/news/2026-06-infection-linked-cancer-therapies.html Tue, 02 Jun 2026 20:00:04 EDT news699624195 Women with abnormal mammograms often have to wait for weeks to find out whether they have breast cancer. Now, researchers at UC San Francisco and UC Berkeley have found a way to help reduce the wait and the worry by using AI to quickly identify those who are most likely to have the disease. By triaging these patients, the AI-guided workflow takes women with abnormal scans through the diagnostic process—from imaging to evaluation and sometimes even biopsy—in a single day. https://medicalxpress.com/news/2026-06-ai-breast-cancer-diagnosis-high.html Tue, 02 Jun 2026 18:00:05 EDT news699632762 A new end-to-end PET imaging approach for osteosarcoma can rapidly and reliably distinguish tumor tissue from normal tissue and accurately assess surgical margins in real time. The novel platform, presented at the Society of Nuclear Medicine and Molecular Imaging 2026 Annual Meeting, has the potential to fundamentally reshape surgical practice for osteosarcoma by enabling precise tumor resection, significantly reducing the risk of local recurrence, and preserving maximum limb function. https://medicalxpress.com/news/2026-06-pet-imaging-platform-rapidly-margins.html Tue, 02 Jun 2026 16:50:01 EDT news699636301 Results of a multicenter clinical trial found that adding the investigational adenoviral-based viral immunotherapy aglatimagene besadenovec (alglatimagene, CAN-2409) to standard radiation therapy improved disease-free survival for patients with intermediate- or high-risk localized prostate cancer. The study was led by researchers at the Johns Hopkins University School of Medicine, Johns Hopkins Kimmel Cancer Center, Department of Radiation Oncology and Molecular Radiation Sciences, and Brady Urological Institute. Findings from the study were published June 1 in The Lancet Oncology. https://medicalxpress.com/news/2026-06-immunotherapy-added-therapy-boosts-survival.html Tue, 02 Jun 2026 16:40:05 EDT news699629521 Researchers from the Icahn School of Medicine at Mount Sinai have discovered a promising new way to improve CAR-T cell therapy for solid tumors such as lung cancer and melanoma. The study, published in Nature Cancer, found that focused irradiation, a targeted therapy that delivers high-energy beams to stun rapidly growing cells such as cancer, can help CAR-T cells survive longer and work more effectively inside tumors. https://medicalxpress.com/news/2026-06-irradiation-car-cell-therapy-solid.html Tue, 02 Jun 2026 16:00:03 EDT news699628561 After surgery for colon cancer, many patients face the question of whether follow-up chemotherapy is necessary to prevent a possible relapse. The decision is particularly difficult in so-called Stage II, the intermediate-risk group. Although around one in five untreated patients suffers a relapse, adjuvant chemotherapy places a significant and, in some cases, unnecessary burden on many patients. A clinical study led by Dresden University Hospital now provides important insights for a robust basis for decision-making. https://medicalxpress.com/news/2026-06-circulating-tumor-dna-benefits.html Tue, 02 Jun 2026 15:20:01 EDT news699619801 Researchers at MUSC Hollings Cancer Center have developed a machine learning tool to identify cancer patients who may be at high risk for financial toxicity—the financial stress and hardship that can accompany a cancer diagnosis and treatment. The study brought together several investigators from the Hollings Cancer Prevention and Control Research Program, reflecting the project's focus on cancer outcomes, survivorship and care delivery. https://medicalxpress.com/news/2026-06-financial-strain-cancer.html Tue, 02 Jun 2026 15:00:07 EDT news699619442 Researchers at Trinity have found that a largely overlooked form of cancer evolution, which drives aggressive disease and poor patient outcomes, is far more widespread than previously thought. Comparing chromosome patterns in these tumors, the team also developed a new method for accurately distinguishing between two leukemias, which could provide information to better guide patient treatment decisions. https://medicalxpress.com/news/2026-06-shrunken-genomes-rapid-cancer-evolution.html Tue, 02 Jun 2026 14:40:03 EDT news699620836 A novel theranostic approach that targets RET—a newly identified biomarker for neuroendocrine prostate cancer—enables high-contrast PET imaging and effective, safe treatment for this highly aggressive malignancy. Because this disease is often poorly visualized with prostate-specific membrane antigen (PSMA)-based imaging, the RET approach offers an important alternative when conventional molecular imaging and PSMA-directed therapies are unsuitable. This research is being presented at the Society of Nuclear Medicine and Molecular Imaging 2026 Annual Meeting. https://medicalxpress.com/news/2026-06-theranostic-approach-effectively-neuroendocrine-prostate.html Tue, 02 Jun 2026 13:50:01 EDT news699544981 A Phase III clinical trial led by Neeraj Agarwal, MD, FASCO, senior director of clinical research at Huntsman Cancer Institute and professor of internal medicine at the University of Utah (the U), has found that a combination prostate cancer treatment could prevent the disease from progressing into a harder-to-treat form of cancer in select patients. https://medicalxpress.com/news/2026-06-prostate-cancer-treatment-disease-clinical.html Tue, 02 Jun 2026 13:00:01 EDT news699618781 Cancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse." Unlike healthy cells, cancer cells rely heavily on specialized helper proteins to keep mitochondria functioning under the high stress of rapid growth. https://medicalxpress.com/news/2026-06-firstinhuman-gamitrinib-disrupt-cancer-cells.html Tue, 02 Jun 2026 10:40:09 EDT news699611762 Stem cell transplantation is the most cost-effective option for long-term care of sickle cell disease in adults when compared with gene therapy and standard of care treatment, according to new research published in Blood . https://medicalxpress.com/news/2026-06-stem-cell-transplantation-effective-gene.html Tue, 02 Jun 2026 10:00:02 EDT news699522541 New Curtin University research has found Australians exposed to asbestos could be falling through the cracks of lung cancer screening programs. The study, published in Occupational and Environmental Medicine, warns thousands of people at high risk of lung cancer may not be identified early enough because asbestos exposure is not being properly considered in current screening efforts. https://medicalxpress.com/news/2026-06-reveals-asbestos-lung-cancer-screening.html Tue, 02 Jun 2026 08:20:05 EDT news699601622 A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who took GLP-1 medications were about 30% less likely to develop breast cancer than those who did not take GLP-1 medications, according to research presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting (Abstract 10506) by Elizabeth McDonald, MD, Ph.D., a professor of Radiology in the University of Pennsylvania Perelman School of Medicine and a practicing breast radiologist at Penn's Abramson Cancer Center. https://medicalxpress.com/news/2026-06-glp-linked-breast-cancer-incidence.html Tue, 02 Jun 2026 08:00:01 EDT news699521701 A new study identifies vgll3 as a key gene that promotes rapid growth and early reproduction while increasing the risk of aging and cancer later in life. The findings provide rare experimental evidence for the theory that evolution favors early-life advantages even at the expense of long-term health. https://medicalxpress.com/news/2026-06-genetic-youth-longevity-uncovered.html Tue, 02 Jun 2026 05:00:04 EDT news699525841 The largest real-world study ever conducted on prostate cancer in Brazil analyzed data from 670,205 patients treated through the Brazilian Unified Health System (SUS) over a 16-year period, between 2008 and 2023. Published in the Journal of Global Oncology, the study included researchers from the D'Or Institute for Research and Education (IDOR) and investigated patterns of diagnosis, treatment, and health care costs related to the disease across the country. The results revealed significant racial inequalities, including a higher frequency of advanced disease at diagnosis among non-white men and differences in therapeutic investment. https://medicalxpress.com/news/2026-06-prostate-cancer-brazil-reveals-racial.html Mon, 01 Jun 2026 22:00:01 EDT news699547599 A new type of peptide receptor radionuclide therapy (PRRT) appears to be safe in metastatic neuroendocrine tumor patients who have exhausted conventional treatment options. This novel approach, presented at the Society of Nuclear Medicine 2026 Annual Meeting, resulted in partial remission of the disease in the majority of patients with advanced cases of neuroendocrine tumors. https://medicalxpress.com/news/2026-06-radiopharmaceutical-therapy-powerful-treatment-option.html Mon, 01 Jun 2026 21:00:01 EDT news699524166 The integration of AI into digital pathology through general-purpose foundation models promises to significantly enhance various tasks, such as cancer detection and subtyping. However, these powerful AI systems also introduce severe vulnerabilities, rendering them susceptible to adversarial attacks. https://medicalxpress.com/news/2026-06-microscopic-noise-multiple-cancer-pathology.html Mon, 01 Jun 2026 18:20:06 EDT news699549601 Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment. While these therapies can produce long-lasting benefits for some patients, many cancers either fail to respond or become resistant over time. https://medicalxpress.com/news/2026-06-tumors-resist-immunotherapy-blocking-mir.html Mon, 01 Jun 2026 18:00:03 EDT news699547624 A new study from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington provides the most comprehensive and conservative analysis to date of alcohol's complex relationship with health, showing clear cancer risks and chronic liver diseases at any level, along with mixed evidence for other cardiometabolic conditions. https://medicalxpress.com/news/2026-06-alcohol-linked-higher-multiple-cancers.html Mon, 01 Jun 2026 17:30:01 EDT news699550921 An artificial intelligence (AI) system that combines breast cancer tissue images with molecular marker data achieves high accuracy in diagnosis, tumor classification, and survival prediction. Details of the research are reported in the International Journal of Data Mining and Bioinformatics. https://medicalxpress.com/news/2026-06-ai-breast-cancer.html Mon, 01 Jun 2026 17:20:02 EDT news699535981 A new study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center shows that the targeted cancer drug selpercatinib can significantly reduce the risk of lung cancer returning in patients with a rare genetic subtype of early-stage non-small cell lung cancer (NSCLC), potentially offering a new treatment option to help keep the disease from coming back after standard therapy. https://medicalxpress.com/news/2026-06-therapy-lung-cancer-recurrence-rare.html Mon, 01 Jun 2026 17:10:01 EDT news699550802 In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert to stem cells. These findings explain why colorectal cancers are so resistant to treatment and can help inform the development of effective therapies for intestinal tumors. https://medicalxpress.com/news/2026-06-colorectal-cancer-backup-mature-gut.html Mon, 01 Jun 2026 16:40:04 EDT news699546302 A simple change in meal timing may help improve outcomes for women with the most common and aggressive form of ovarian cancer, a new study suggests. https://medicalxpress.com/news/2026-06-short-term-fasting-boost-chemo.html Mon, 01 Jun 2026 16:20:03 EDT news699529523 Previously, immature overall survival results of the NRG Oncology GY018 (NRG-GY018) trial suggested that the use of the immunotherapy drug pembrolizumab in combination with chemotherapy improved overall survival for patients with advanced stage or recurrent endometrial cancer when compared to chemotherapy alone. Notably, this benefit was observed in both the mismatch repair proficient (pMMR) and mismatch repair deficient (dMMR) populations. https://medicalxpress.com/news/2026-06-addition-immunotherapy-survival-benefit-trial.html Mon, 01 Jun 2026 16:00:07 EDT news699546062 Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity. These mutations are already guiding more personalized treatments. https://medicalxpress.com/news/2026-06-tp53-gene-mutations-affect-lung.html Mon, 01 Jun 2026 15:40:01 EDT news699545941