https://medicalxpress.com/cancer-news/ en-us Latest medical news and research in Oncology Researchers from the Biosciences and Chemistry Department at Durham University have discovered that combinations of metals linked to smoking and pollution may help lung cancer become resistant to chemotherapy. The study, carried out with Pleco Therapeutics (Netherlands), found that several metals can work together inside tumor cells, making cancer treatment far less effective. https://medicalxpress.com/news/2026-08-heavy-metals-lung-cancer-resist.html Tue, 18 Aug 2026 08:40:07 EDT news706258280 New research from The Daffodil Centre, a partnership between Cancer Council NSW and the University of Sydney, suggests that Australia will experience a substantial increase in the number of people living with or beyond cancer over the coming decades and highlights the growing importance of prevention, early detection, health care and survivorship support systems. https://medicalxpress.com/news/2026-08-million-australians-cancer.html Tue, 18 Aug 2026 08:20:03 EDT news706258250 A research group has revealed through studies in humans and mice that a subset of clear cell ovarian cancers, which have been considered difficult to treat with anticancer drugs and immunotherapy, responds to immunotherapy. https://medicalxpress.com/news/2026-08-immunotherapy-effective-subtype-difficult-ovarian.html Mon, 17 Aug 2026 17:20:05 EDT news706205462 For patients facing a diagnosis of glioblastoma—one of the most aggressive and devastating forms of brain cancer—the standard path forward has long meant invasive open-skull surgery and a daunting prognosis. https://medicalxpress.com/news/2026-08-laser-therapy-weapon-deadly-brain.html Mon, 17 Aug 2026 16:00:06 EDT news706176001 One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging can fully resolve. During surgery, neurosurgeons must remove as much tumor as possible while preserving critical brain functions. This makes accurate intraoperative assessment of tumor infiltration essential for more precise surgical decision-making. https://medicalxpress.com/news/2026-08-ultra-glioma-margins-3d-minutes.html Mon, 17 Aug 2026 15:00:01 EDT news706196041 The Medicines Patent Pool (MPP) is a not-for-profit organization founded in 2010 with the support of the United Nations. Its mission is to improve access to essential medicines in low and middle-income countries (LMICs). It negotiates voluntary licenses with patent holders—typically pharmaceutical companies—before granting nonexclusive and geographically limited sublicenses to manufacturers in targeted countries, where the originator companies—that is, those that bring new medicinal products to market—typically are not active. This results in low or no royalty payments by sublicensees to patent holders, together with competition among multiple sublicensees in the targeted geographic markets, which helps reduce the price of medicines. https://medicalxpress.com/news/2026-08-medicines-patent-pool-access-essential.html Mon, 17 Aug 2026 13:40:03 EDT news706186682 Approximately 65% of U.S. adults report consuming one or more sugar-sweetened beverages every day. Mass General Brigham Cancer Institute researchers found that consuming these drinks daily was associated with an increased risk of developing gastric cancer, while artificially sweetened beverages were not associated with an increased risk. Results are published in the journal Gastro Hep Advances. https://medicalxpress.com/news/2026-08-people-consume-sugar-sweetened-beverages.html Mon, 17 Aug 2026 12:40:11 EDT news706189144 Obesity can weaken the immune system's tumor-killing responses in lung cancer, leading to disease progression, but a new study by experts at Roswell Park Comprehensive Cancer Center reveals that exercise may reverse this effect. https://medicalxpress.com/news/2026-08-obesity-weakens-anti-tumor-immune.html Mon, 17 Aug 2026 12:40:07 EDT news706185962 A new study from London Health Sciences Centre Research Institute (LHSCRI) shows that expanded genetic testing can help match cancer patients with more personalized treatment options, with nearly one in three found eligible for therapies not typically used for their specific type of cancer based on the unique DNA of their tumor. https://medicalxpress.com/news/2026-08-advanced-genetic-treatment-options-cancer.html Mon, 17 Aug 2026 11:40:07 EDT news706182421 Of more than 500 occupations in the United States, flight attendants and pilots have the highest and second-highest proportions of radiation-related cancer deaths, a new study has found. https://medicalxpress.com/news/2026-08-flight-greater-cancer-death.html Mon, 17 Aug 2026 11:00:08 EDT news706181341 Age 45: You've made it to middle age, you're ideally entering your prime earning years and, if you're like most adults, your doctor tells you that it's time to consider your first colonoscopy to screen for colorectal cancer. https://medicalxpress.com/news/2026-08-age-health-screenings.html Mon, 17 Aug 2026 08:40:06 EDT news706170062 For more than a decade, CAR-T cell therapy has been one of the biggest breakthroughs in cancer medicine. By reprogramming a patient's own immune cells to attack cancer, doctors have produced remarkable results against certain blood cancers, offering hope to patients who once had few treatment options. https://medicalxpress.com/news/2026-08-car-cells-solid-tumors-cancer.html Sun, 16 Aug 2026 12:00:01 EDT news705918650 Immunotherapy that targets tumor-associated macrophages, a type of immune cell in the tumor microenvironment, works only if the cells have a functional system of molecules that enables them to respond to the treatment. This is shown in a new study from Karolinska Institutet, published in the journal Nature Communications. The findings may help identify which tumors could respond to the treatment and open up new combination therapies for cancer. https://medicalxpress.com/news/2026-08-mechanism-macrophage-cancer-immunotherapy.html Fri, 14 Aug 2026 14:20:03 EDT news705932761 Every year, lung cancer kills more than 100,000 people in the United States. Smoking is the leading risk factor for lung cancer, but other environmental exposures can also contribute to the disease. https://medicalxpress.com/news/2026-08-drug-inflammatory-enzyme-lung-cancer.html Fri, 14 Aug 2026 14:00:06 EDT news705921421 Researchers at Karolinska Institutet report in the Journal of Experimental & Clinical Cancer Research that sodium selenite not only can damage tumor cells but also influence characteristics linked to tumor aggressiveness and treatment response. The findings are based on both cell experiments and analyses of tumor tissue from patients with pancreatic cancer. https://medicalxpress.com/news/2026-08-selenite-key-properties-pancreatic-cancer.html Fri, 14 Aug 2026 13:00:01 EDT news705929562 Breast cancer is the most common form of cancer among women in Germany: Around 1 in 8 women will develop it during their lifetime. In around 5% to 10% of cases, the condition is caused by a hereditary predisposition. Thirteen risk genes have currently been identified for genetic testing, including the BRCA1 and BRCA2 genes. Variations (mutations) in these genes are associated with a significantly increased risk of breast cancer. https://medicalxpress.com/news/2026-08-genome-analysis-uncovers-candidate-genes.html Fri, 14 Aug 2026 12:20:04 EDT news705928442 Researchers at WashU Medicine have shown that cells originating in bone and best known for their role in bone formation are recruited to primary breast tumors, where they become cancer-associated fibroblasts, a type of cell that helps create the environment tumors need to grow. https://medicalxpress.com/news/2026-08-breast-cancers-bone-cells-tumor.html Fri, 14 Aug 2026 11:40:01 EDT news705924541 The proportion of women with early breast cancer who receive chemotherapy varies significantly across different regions of Sweden. A study from Karolinska Institutet, published in the journal Breast Cancer Research, shows that these differences may affect survival among women 65 and older. https://medicalxpress.com/news/2026-08-regional-differences-chemotherapy-treatment-breast.html Thu, 13 Aug 2026 18:40:01 EDT news705853441 More than a decade ago, Dr. Matthew Hebb was treating patients with Parkinson's disease using deep brain stimulation by implanting tiny electrodes into the brain and delivering electrical signals to control tremors. He wondered if the same basic technology could be used against brain cancer. https://medicalxpress.com/news/2026-08-electric-fields-aggressive-brain-cancer.html Thu, 13 Aug 2026 18:20:06 EDT news705861001 Since its development at the University of Michigan more than two decades ago, histotripsy has progressed from an experimental method for mechanically destroying tissue to a US Food and Drug Administration (FDA)–cleared treatment for liver tumors. The noninvasive technique uses short, high-pressure ultrasound pulses to generate microscopic bubble clouds that break apart targeted tissue without heat. https://medicalxpress.com/news/2026-08-intermediate-histotripsy-dose-boosts-tumor.html Thu, 13 Aug 2026 16:40:06 EDT news705852602 Using a photochemically driven labeling technique, a Cornell-led research group has devised a strategy for capturing cancer-specific protein–protein interactions, which could one day lead to targeted therapies for prostate, small-cell lung, pancreatic and other deadly forms of cancer. https://medicalxpress.com/news/2026-08-cancer-specific-myc-reveals-overlooked.html Thu, 13 Aug 2026 16:40:05 EDT news705850081 Researchers at Peter Mac have discovered why breast cancer treatment stops working for some patients, uncovering the unexpected role of one of the body's most important cancer-fighting proteins. The study, published in Nature, revealed that the retinoblastoma (Rb) protein—long considered one of the body's natural brakes on cancer growth—has a more complex function than previously understood. https://medicalxpress.com/news/2026-08-rb-unexpected-estrogen-responsive-genes.html Thu, 13 Aug 2026 16:20:03 EDT news705849422 Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's immune system. The finding could pave the way for the development of more effective cancer immunotherapies. https://medicalxpress.com/news/2026-08-scientists-uncover-hidden-cancer-cells.html Thu, 13 Aug 2026 16:00:02 EDT news705849242 Although there are many cancer treatments available today that effectively eliminate abnormal cells, these therapies may also damage healthy cells, leading to unwanted side effects. https://medicalxpress.com/news/2026-08-cancer-therapeutic-tumors-limiting-exposure.html Thu, 13 Aug 2026 15:40:06 EDT news705844562 Gliomas are malignant brain tumors that originate from glial cells, which do not produce electrical impulses like neurons but instead support neurons by maintaining their structure and function. They are the most common form of brain cancer in adults and hijack normal neuronal signaling, especially the protein neuroligin-3 (NLGN3), released by active nerve cells, to fuel their own growth and spread into healthy brain tissue. Researchers wanted to uncover how NLGN3 interacts with glioma cells and healthy OPCs, and the role it normally plays in healthy brain cells. https://medicalxpress.com/news/2026-08-brain-cancer-cells-exploit-nerve.html Thu, 13 Aug 2026 15:20:02 EDT news705830630 A research team at The Hong Kong Polytechnic University (PolyU) has developed a patient-centric "Artificial Intelligence (AI) Virtual Patient Simulation System," overcoming the limitations of conventional static diagnosis. https://medicalxpress.com/news/2026-08-ai-digital-twin-platform-advances.html Thu, 13 Aug 2026 15:00:03 EDT news705850442 Researchers have developed a novel AI model that can analyze a routine whole-slide histopathology image and simultaneously predict cancer subtype, specific genetic mutations and survival outcomes across 32 different solid cancers rather than focusing on a single cancer type. The findings from the study in The American Journal of Pathology highlight the potential of computational pathology to connect routine diagnostic imaging with molecular oncology. https://medicalxpress.com/news/2026-08-ai-accurately-key-gene-mutations.html Thu, 13 Aug 2026 12:20:13 EDT news705841762 Three decades after UC San Francisco pioneered "active surveillance" for patients with low-risk prostate cancer, a new study has found that the vast majority of veterans with the diagnosis pursued this option instead of treatment. https://medicalxpress.com/news/2026-08-early-prostate-cancer-surveillance-choice.html Thu, 13 Aug 2026 11:00:04 EDT news705833174 An updated clinical guideline from the American Society for Radiation Oncology (ASTRO) provides evidence-based recommendations on the use of radiation therapy to treat adult patients with pancreatic cancer. https://medicalxpress.com/news/2026-08-astro-guideline-therapy-pancreatic-cancer.html Thu, 13 Aug 2026 10:00:06 EDT news705831138 Researchers at Moffitt Cancer Center have developed three mathematical biomarkers that may help physicians personalize adaptive therapy for prostate cancer by predicting treatment outcomes early in treatment. The biomarkers are specialized mathematical measures calculated from routine prostate-specific antigen (PSA) blood tests. https://medicalxpress.com/news/2026-08-mathematical-personalize-therapy-prostate-cancer.html Thu, 13 Aug 2026 08:20:01 EDT news705821247