https://medicalxpress.com/medications-news/ en-us Latest medical news and research in Clinical pharmacology Chronic pain, including arthritis pain, affects more than one-third of U.K. adults. Current painkillers such as methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs) work by damping down the immune system, which is overproducing inflammatory agents that cause pain, but relief is often short-lived and incomplete, and they can leave patients more vulnerable to infection. https://medicalxpress.com/news/2026-09-body-warmth-sensor-secretly-pain.html Thu, 17 Sep 2026 12:20:07 EDT news708863822 Scroll through social media these days and you'll likely come across someone injecting themselves with a clear liquid, raving about how it's changed their body for the better, improved their recovery or maybe their skin. https://medicalxpress.com/news/2026-09-peptides-social-media-platforms-health.html Thu, 17 Sep 2026 09:40:01 EDT news708847904 Medical assistance can help women suffering from severe nausea and vomiting during pregnancy, but insufficient recognition of hyperemesis gravidarum (HG) means many are not getting the help they need to overcome this severe and debilitating form of morning sickness. https://medicalxpress.com/news/2026-09-greater-access-women-nausea-pregnancy.html Thu, 17 Sep 2026 07:00:04 EDT news708840661 An existing anti-seizure drug slows the growth of a devastating group of childhood cancers, new Stanford Medicine-led research has shown. The tumors, called diffuse midline gliomas, strike the brain and spinal cord. They affect 300 to 400 U.S. children per year and have a five-year survival rate of about 1%. https://medicalxpress.com/news/2026-09-anti-seizure-drug-aggressive-childhood.html Thu, 17 Sep 2026 05:00:03 EDT news708794221 U.S. health officials knowingly relied on a compromised algorithm to detect signals of harm from mRNA COVID-19 vaccines and silenced efforts to fix it, finds an investigation published by The BMJ today. https://medicalxpress.com/news/2026-09-sidelined-flawed-covid-vaccine-safety.html Wed, 16 Sep 2026 18:30:01 EDT news708798361 Hot flashes and night sweats—collectively called vasomotor symptoms—are among the most common and disruptive symptoms of menopause. They affect almost 40% of women in the lead-up to menopause, known as perimenopause. https://medicalxpress.com/news/2026-09-menopause-drug-veoza-hormone-therapy.html Wed, 16 Sep 2026 14:40:09 EDT news708785874 To defeat multidrug-resistant superbugs, bacterial defenses must be confronted wherever they may emerge, from basic genetic mutations in a laboratory to complex real-world transmission in hospital rooms. A new trio of studies published in Antimicrobial Agents and Chemotherapy and researched by the laboratory of Barry N. Kreiswirth, Ph.D., at the Hackensack Meridian Center for Discovery and Innovation (CDI) demonstrates how an integrated approach might yet expose and overcome these diverse survival mechanisms. https://medicalxpress.com/news/2026-09-superbugs-evade-antibiotics-vulnerable-patients.html Wed, 16 Sep 2026 13:00:01 EDT news708780001 Pain is a natural protective mechanism that alerts the body to actual or potential injury. But when nerves themselves are damaged, they can generate abnormal pain signals even in the absence of a new injury. This condition, known as neuropathic pain, can be persistent and difficult to treat. Medicines can sometimes provide inadequate relief or cause unwanted effects, creating a need for treatments that can reduce abnormal pain without interfering with normal pain sensation. https://medicalxpress.com/news/2026-09-nav17-approach-relief-nerve-pain.html Wed, 16 Sep 2026 11:20:09 EDT news708771248 UC San Francisco researchers are weighing in on one of the biggest challenges in psychedelic science, arguing that clinical trials need more convincing placebo treatments to better measure the drugs' true effects. https://medicalxpress.com/news/2026-09-psychedelic-clinical-trials.html Wed, 16 Sep 2026 11:00:10 EDT news708683883 What if you could heal like Wolverine? https://medicalxpress.com/news/2026-09-compounding-problem-peptides.html Wed, 16 Sep 2026 09:40:10 EDT news708767101 Streptococcus pneumoniae is a bacterial pathogen that causes life-threatening infections, including pneumonia and meningitis. These infections are commonly treated with antibiotics, but antibiotics are becoming less effective against S. pneumoniae over time because of changes in the pathogen that cause drug resistance. This phenomenon, called antimicrobial resistance, is resulting in significant health care costs and deaths around the world. In a new study published by Wiley in Advanced Science, researchers used artificial intelligence (AI) to identify approved drugs that may be effective against S. pneumoniae. https://medicalxpress.com/news/2026-09-drugs-resistant-strains-ai-advances.html Wed, 16 Sep 2026 03:10:01 EDT news708701222 Swinburne University of Technology and Entropy Neurodynamics' world's first IV-infused psilocin binge-eating disorder trial has led to improvements in all participants. https://medicalxpress.com/news/2026-09-world-psilocin-binge-disorder-trial.html Tue, 15 Sep 2026 17:20:07 EDT news708685310 Patients with major depressive disorder (MDD) and an inadequate response to standard antidepressants who received add-on treatment with the drug lumateperone had significantly improved sexual function, according to a new study led by a University of Virginia School of Medicine researcher. https://medicalxpress.com/news/2026-09-drug-sexual-function-patients-depression.html Tue, 15 Sep 2026 15:00:08 EDT news708697330 An experimental drug has been shown to improve symptoms, exercise capacity and heart failure status in patients with an inherited heart disease, according to a pair of newly published studies. https://medicalxpress.com/news/2026-09-experimental-drug-potential-hard-heart.html Tue, 15 Sep 2026 14:20:08 EDT news708695041 Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by changes involving amyloid-beta and tau proteins in the brain. Lecanemab is an anti-amyloid therapy approved for people with early AD that has been shown to slow disease progression. However, treatment responses can vary among individuals, creating a need for accessible ways to monitor biological changes during therapy. https://medicalxpress.com/news/2026-09-reveals-blood-biomarker-tracks-response.html Mon, 14 Sep 2026 18:00:02 EDT news708611726 Researchers from the University of Liverpool and the University of Zurich have identified a potential safety consideration involving levetiracetam, one of the world's most commonly prescribed antiseizure medications. https://medicalxpress.com/news/2026-09-common-epilepsy-drug-levetiracetam-potential.html Mon, 14 Sep 2026 14:40:07 EDT news708608641 Cefepime is a fourth-generation antibiotic widely used to treat serious bacterial infections and febrile neutropenia—a fever in patients with abnormally low white blood cell counts. Unlike many antibiotics that are falling prey to antimicrobial resistance, cefepime is relatively stable against AmpC β-lactamases, giving it an advantage against bacteria that produce these enzymes. However, scientists are concerned that this widely effective antibiotic may increase the risk of death, a concern first brought to light by a 2007 meta-analysis. https://medicalxpress.com/news/2026-09-common-antibiotic-linked-higher-death.html Mon, 14 Sep 2026 10:10:02 EDT news708598913 Two people can take the same dose of the same medicine and have very different results. One may improve, while the other gets little benefit or develops serious side effects. Part of the explanation often lies in their genes. https://medicalxpress.com/news/2026-09-pharmacogenomics-genes-doctors-medicine-dose.html Mon, 14 Sep 2026 09:20:01 EDT news708593942 Adding zipalertinib to platinum-pemetrexed chemotherapy significantly improved progression-free survival in patients receiving first-line treatment for advanced non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations, according to results presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-zipalertinib-chemotherapy-significantly-free-survival.html Sun, 13 Sep 2026 21:50:10 EDT news708350641 New results from the global phase 1/2 ARROS-1 trial showed clinically meaningful activity with zidesamtinib in patients with advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC) who had not previously received a tyrosine kinase inhibitor (TKI). The findings were presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-zidesamtinib-response-ros1-positive-lung.html Sun, 13 Sep 2026 21:50:04 EDT news708350762 A new modeling study published in The Lancet suggests that U.S. Medicare's new "Most-Favored-Nation" pricing policy, which ties what Medicare pays for medicines to prices charged in other high-income countries, could push pharmaceutical manufacturers to raise prices or delay launches. For about three in four medicines studied, the resulting Medicare savings would be worth almost four times that medicine's entire annual sales in the country used to set its price, potentially giving manufacturers a strong incentive to change how they price and launch products outside the U.S. https://medicalxpress.com/news/2026-09-medicare-pricing-policies-reshape-global.html Sun, 13 Sep 2026 18:30:01 EDT news708350041 Not all cancer cells are the same, and neither are their responses to drugs. Finding the right drug for the right cancer cell is a long battle in drug development and in designing effective treatments. A new AI tool called ProteinTalks makes this task easier by accurately predicting whether a drug will be effective against a cancer cell line, finding new drug combinations and identifying proteins linked to drug resistance. https://medicalxpress.com/news/2026-09-ai-virtual-cell-protein-dynamics.html Sat, 12 Sep 2026 11:20:01 EDT news708342129 An investigational EGFR x HER3 antibody-drug conjugate demonstrated promising efficacy with a tolerable safety profile in patients with previously treated EGFR-mutated non-small cell lung cancer (NSCLC), supporting selection of the 2.5 mg/kg dose for evaluation in the global Phase III IZABRIGHT-Lung01 registrational study. https://medicalxpress.com/news/2026-09-egfr-her3-therapy-phase-iii.html Sat, 12 Sep 2026 05:20:10 EDT news708247867 Extended-interval dosing regimens of tarlatamab demonstrated efficacy, safety and pharmacokinetic profiles generally consistent with the established every-two-week regimen in patients with previously treated small cell lung cancer (SCLC), according to results from the randomized Phase II DeLLphi-309 study presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-interval-tarlatamab-dosing-safety-previously.html Sat, 12 Sep 2026 05:20:01 EDT news708248125 Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have identified a promising antiviral compound that can inhibit a range of enteroviruses, including Enterovirus D68 (EV-D68), an emerging respiratory virus linked to severe respiratory illness and acute flaccid myelitis, a condition that can cause paralysis. https://medicalxpress.com/news/2026-09-broad-spectrum-antiviral-candidate-enteroviruses.html Fri, 11 Sep 2026 20:00:01 EDT news708352510 For a patient having their wisdom teeth removed, the days after surgery can bring an important question: How much pain medication will I actually need? https://medicalxpress.com/news/2026-09-ai-tools-postoperative-opioid-individualized.html Fri, 11 Sep 2026 15:20:01 EDT news708348904 Cancer treatments, including chemotherapy and radiation therapy, give a growth advantage to cells with particular genetic changes in healthy tissue, new research finds. https://medicalxpress.com/news/2026-09-chemotherapy-darwinian-battleground-bodies.html Fri, 11 Sep 2026 05:00:07 EDT news708270961 For Judy Donnelly, participating in a UConn Health research study meant driving from Windham to Farmington, drinking four packets of a supplement each day and undergoing a comprehensive series of tests designed to measure everything from her strength and body composition to her cognitive function. https://medicalxpress.com/news/2026-09-ketone-supplement-trial-aging-older.html Thu, 10 Sep 2026 21:20:04 EDT news708262484 A new Ontario-wide study reveals that common medications, from statins to iron supplements, are quietly setting off prescribing cascades that leave older adults unknowingly taking drugs to treat side effects of other drugs. https://medicalxpress.com/news/2026-09-potentially-drug-combinations-older-adults.html Thu, 10 Sep 2026 18:30:01 EDT news708257281 Every year, between 80,000 and 140,000 people die from snakebites worldwide. Hundreds of thousands more are left with amputated limbs or permanent disabilities. https://medicalxpress.com/news/2026-09-snakebites-tens-thousands-year.html Thu, 10 Sep 2026 18:00:04 EDT news708262657