https://medicalxpress.com/medications-news/ en-us Latest medical news and research in Clinical pharmacology A recent paper in Nature Biotechnology examines problems and solutions for antibody-based therapies for solid pancreatic cancers and tumors of the head and neck. https://medicalxpress.com/news/2026-06-cell-platform-tracks-antibody-drug.html Wed, 03 Jun 2026 05:00:02 EDT news699614161 The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. Results from a study in the Journal of Internal Medicine suggest that this may prompt a clinician to run tests to uncover an asymptomatic bladder tumor. https://medicalxpress.com/news/2026-06-aspirin-unmask-silent-bladder-cancer.html Wed, 03 Jun 2026 03:10:01 EDT news699611881 A heart attack is far from an isolated, acute event. The consequences of an attack can cause serious and lasting damage, including heart failure. However, researchers and clinicians have been unable to determine a standardized treatment route to prevent long-term structural changes to the heart after a heart attack. https://medicalxpress.com/news/2026-06-combination-mrnas-mitigates-heart-failure.html Tue, 02 Jun 2026 20:40:01 EDT news699613827 A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Over the years, many novel ADC therapies have been approved for treating various types of cancers. https://medicalxpress.com/news/2026-06-infection-linked-cancer-therapies.html Tue, 02 Jun 2026 20:00:04 EDT news699624195 GLP-1 receptor agonist drugs, used for the treatment of diabetes—and more recently, weight loss—are associated with a significantly lower long-term risk of knee replacement surgery as a result of osteoarthritis, finds an analysis of medical records data, published in the open-access journal Regional Anesthesia & Pain Medicine. https://medicalxpress.com/news/2026-06-glp-agonists-linked-significantly-term.html Tue, 02 Jun 2026 18:30:02 EDT news699612182 Millions of Americans are currently taking GLP-1 medications such as Ozempic or Wegovy for weight loss. But along with the fat, many are quietly losing something else: muscle. Unlike fat, muscle doesn't return quickly, and muscle loss can have deleterious effects on strength, mobility, and overall health. https://medicalxpress.com/news/2026-06-drug-muscle-glp-weight-loss.html Tue, 02 Jun 2026 18:20:04 EDT news699634921 Acetaminophen remains the recommended first-line medication to treat pain and fever during pregnancy, according to an updated statement from the Society for Maternal-Fetal Medicine (SMFM). A comprehensive review of the available scientific evidence does not establish a causal relationship between acetaminophen taken during pregnancy and an increased risk of autism spectrum disorders and attention deficit and hyperactivity disorder (ADHD) in children, according to SMFM. The work is published in the journal Pregnancy. https://medicalxpress.com/news/2026-06-acetaminophen-reaffirmed-line-medication-pain.html Tue, 02 Jun 2026 16:30:01 EDT news699634981 For the roughly 300,000 Americans living with a spinal cord injury (SCI), chronic pain is often a part of daily life, and—for many—opioids are prescribed to combat it. In addition to the serious physical considerations, mental health concerns are prevalent in this population. Depression is common among individuals with SCIs, whose risk is three times higher than that of the general population. https://medicalxpress.com/news/2026-06-complex-relationship-opioids-suicidal-ideation.html Tue, 02 Jun 2026 16:10:06 EDT news699633661 You've probably heard of Ozempic or Wegovy. These are the injectable drugs that have become household names for weight loss and diabetes. https://medicalxpress.com/news/2026-06-glp1-drugs-ozempic-weight-loss.html Tue, 02 Jun 2026 14:00:04 EDT news699615781 Southwest Research Institute evaluated NASA's medication handling practices, which currently call for removing medications from their original packaging and storing them in resealable plastic bags. Although this allows astronauts to economize stowage for spaceflight, SwRI's investigation found that active pharmaceutical ingredients degrade at a higher rate when stored in bags. https://medicalxpress.com/news/2026-06-nasa-medication-storage-protocols.html Tue, 02 Jun 2026 12:40:04 EDT news699615182 Cancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse." Unlike healthy cells, cancer cells rely heavily on specialized helper proteins to keep mitochondria functioning under the high stress of rapid growth. https://medicalxpress.com/news/2026-06-firstinhuman-gamitrinib-disrupt-cancer-cells.html Tue, 02 Jun 2026 10:40:09 EDT news699611762 The Global Hypertension Report by the World Health Organization (WHO) revealed that 1.4 billion people were living with hypertension in 2024. Yet, only a little over one in five of those diagnosed have it under control, whether through medication or by managing modifiable health risks. Fear of side effects is a major barrier to effective blood pressure control, often discouraging people from starting medication, accepting higher doses, or staying on treatment for the long term. https://medicalxpress.com/news/2026-06-high-blood-pressure-drug-combinations.html Tue, 02 Jun 2026 10:00:05 EDT news699612171 A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who took GLP-1 medications were about 30% less likely to develop breast cancer than those who did not take GLP-1 medications, according to research presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting (Abstract 10506) by Elizabeth McDonald, MD, Ph.D., a professor of Radiology in the University of Pennsylvania Perelman School of Medicine and a practicing breast radiologist at Penn's Abramson Cancer Center. https://medicalxpress.com/news/2026-06-glp-linked-breast-cancer-incidence.html Tue, 02 Jun 2026 08:00:01 EDT news699521701 Traditional Knowledge has supported health and well-being practices for thousands of years using medicinal plants and cultural medicines. But how can that knowledge be applied appropriately for use in scientific drug discovery? https://medicalxpress.com/news/2026-06-indigenous-benchmarks-ethical-cultural-medicine.html Tue, 02 Jun 2026 07:40:02 EDT news699601262 Several non-profit organizations announced Monday they are ramping up efforts to rapidly develop a vaccine for the rare strain of Ebola driving a deadly outbreak in the Democratic Republic of Congo. https://medicalxpress.com/news/2026-06-ebola-vaccine.html Mon, 01 Jun 2026 20:00:01 EDT news699541812 Three-quarters of people who respond well to the newest types of biologics for psoriasis can safely reduce their dosage, often even by half. These medications then work just as effectively, according to a study led by Radboud University Medical Center and Ghent University Hospital. The finding results in fewer injections and saves up to €8,500 (~$9,900) per patient per year. The study is published in The Lancet Regional Health—Europe. https://medicalxpress.com/news/2026-06-medicines-dosage-stable-psoriasis.html Mon, 01 Jun 2026 19:30:01 EDT news699521941 Amid growing concern about the widespread off-label use of sedative medications for sleep problems, Flinders University researchers have led a world-first clinical trial examining how a commonly prescribed "sleeping pill" affects sleep, breathing and next-day performance. https://medicalxpress.com/news/2026-06-commonly-medication-problems-alarm-bells.html Mon, 01 Jun 2026 16:00:05 EDT news699524161 In Las Vegas May 2026, athletes compete in an international sporting event that explicitly allows them to use performance-enhancing drugs (PEDs). The Enhanced Games openly encourages competitors to use substances banned in virtually every mainstream sport, including anabolic steroids, erythropoietin and peptide hormones. Organizers have claimed that with proper medical supervision, this is safe. It is a bold proposition and, according to Professor Ian Boardley of the University of Birmingham, a dangerous one. https://medicalxpress.com/news/2026-06-dangers-legitimizing-doping.html Mon, 01 Jun 2026 15:40:05 EDT news699529495 FDA-approved carbon copies of brand-name drugs with expired patents—over the last 30 years, these generic drugs have saved trillions of dollars for hundreds of millions of people. https://medicalxpress.com/news/2026-06-global-access-glp-drugs.html Mon, 01 Jun 2026 13:40:05 EDT news699535682 Millions of people in the UK suffer from joint pain and arthritis. But with long wait times for scans, specialist appointments, physiotherapy, and joint replacement surgery, many people turn to over-the-counter medicines, such as ibuprofen, to manage their joint pain, stay active, and continue working. https://medicalxpress.com/news/2026-06-ibuprofen-joint-pain.html Mon, 01 Jun 2026 13:40:01 EDT news699528662 Once confined to niche bodybuilding forums and hardcore gyms, unproven injectable peptides are now being openly marketed online to the average gym-goer by social media influencers—and regulators struggling to keep up. https://medicalxpress.com/news/2026-05-dangerous-peptides-social-media-struggling.html Sun, 31 May 2026 16:00:02 EDT news699106145 Patients in London have received a pioneering new gene editing therapy that lowers "bad" cholesterol after a single infusion, as part of a study involving UCL scientists. https://medicalxpress.com/news/2026-05-gene-treatment-lowers-bad-cholesterol.html Sun, 31 May 2026 11:00:01 EDT news699200363 New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining asthma control and improving key clinical outcomes. The findings were published in The Lancet Respiratory Medicine. https://medicalxpress.com/news/2026-05-tezepelumab-severe-asthma-patients-oral.html Sat, 30 May 2026 14:00:01 EDT news699274281 Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant to a specific form of cell death known as ferroptosis.⮐ https://medicalxpress.com/news/2026-05-inhibitor-outcome-effect-reshape-ferroptosis.html Sat, 30 May 2026 06:08:06 EDT news699340017 A new study by researchers at the University of Sydney has shown that taking cannabidiol (CBD) can significantly reduce chronic neuropathic pain in those suffering from it. The findings of the randomized placebo-controlled trial, published in eClinicalMedicine, demonstrated that taking CBD over a six-week period reduced pain by approximately 14%, compared to 6.5% from the placebo. https://medicalxpress.com/news/2026-05-cannabidiol-significantly-chronic-pain-nerve.html Fri, 29 May 2026 12:00:02 EDT news699268613 A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. https://medicalxpress.com/news/2026-05-simulation-uncovers-tuberculosis-drug-candidates.html Fri, 29 May 2026 11:20:05 EDT news699269760 Scientists at Université de Montréal have figured out how metformin—a common drug that's used to treat type-2 diabetes and that may cut the risk of developing cancer and even help humans and other mammals live longer—actually works. https://medicalxpress.com/news/2026-05-metformin-diabetes-reshape-aging-cancer.html Fri, 29 May 2026 09:20:08 EDT news699263013 The targeted therapy sunvozertinib was more effective than standard platinum-based chemotherapy as a first-line treatment for patients with advanced non-small cell lung cancer (NSCLC) driven by EGFR exon 20 insertion mutations (EGFR exon20ins), according to new research from The University of Texas MD Anderson Cancer Center. https://medicalxpress.com/news/2026-05-drug-outperforms-chemotherapy-patients-hard.html Fri, 29 May 2026 09:00:05 EDT news699262944 A new way of designing antibiotics could support the discovery of new treatments for drug-resistant infections. It could also help revive antibiotics that have lost effectiveness because bacteria have evolved over time to survive the drugs meant to kill them. https://medicalxpress.com/news/2026-05-antibiotic-drug-resistant-infections.html Fri, 29 May 2026 06:00:01 EDT news699166490 There is good news for patients with rheumatoid arthritis. Research from Aarhus University and Aarhus University Hospital may have opened the door to an entirely new way of reducing inflammation in the joints. The study is published in the journal EULAR Rheumatology Open. https://medicalxpress.com/news/2026-05-treatment-rheumatoid-arthritis.html Thu, 28 May 2026 21:00:03 EDT news699183640