https://medicalxpress.com/overweight-obesity-news/ en-us Latest health news and information about Weight Management People who carry genetic variations linked to obesity are more likely to be heavier now than individuals with the same variants who were born before the recent obesity epidemic. Liam Wright of University College London and colleagues report these findings in the journal PLOS Genetics. https://medicalxpress.com/news/2026-06-link-genetics-bmi-stronger-obesity.html Thu, 18 Jun 2026 14:00:07 EDT news700990922 Weight-loss jabs are the latest craze for shedding a few pounds. Their effect has been dramatic, with drugs such as Ozempic and Wegovy (semaglutide) causing users to lose up to 15% of their body fat on average. https://medicalxpress.com/news/2026-06-weightloss-drugs-dont-people.html Wed, 17 Jun 2026 16:20:06 EDT news700920542 Liver cancer is one of the fastest-rising causes of cancer-related deaths in the UK and the third-leading cause of cancer deaths worldwide. https://medicalxpress.com/news/2026-06-liver-cancer-deaths-rapidly-tackling.html Wed, 17 Jun 2026 14:40:03 EDT news700920302 Yo-yo dieters who struggle to lose weight and keep it off may achieve better results by following an intermittent fasting diet, rather than traditional calorie counting. An Adelaide University study focusing on the psychological aspects of both intermittent fasting and calorie restriction compared the effects the diets had on eating behaviors, mood, sleep and quality of life. The research is published in the journal Clinical Nutrition. https://medicalxpress.com/news/2026-06-diet-intermittent-fasting-weight-loss.html Wed, 17 Jun 2026 09:40:03 EDT news700906801 The rapid rise of GLP-1 medications such as semaglutide and tirzepatide has transformed obesity treatment. Still, experts say medications alone are not enough to address one of the nation's most pressing chronic diseases. https://medicalxpress.com/news/2026-06-glp-1s-chapter-obesity.html Wed, 17 Jun 2026 05:00:07 EDT news700818061 A new article published in Globalization and Health warns that the rapid rise of GLP-1 weight-loss drugs in high-income countries could have unintended consequences for food environments in low- and middle-income countries. https://medicalxpress.com/news/2026-06-weight-loss-drugs-reshape-food.html Tue, 16 Jun 2026 18:00:05 EDT news700847582 Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have become popular for weight loss, but results vary from person to person and from drug to drug. Venky Soundararajan and colleagues explored the full range of responses to tirzepatide (e.g., Mounjaro or Zepbound) and semaglutide (e.g., Ozempic, Wegovy or Rybelsus) by analyzing de-identified electronic health records for matched cohorts of 10,339 tirzepatide-treated and 10,339 semaglutide-treated patients. In the real world, outcomes ranged from minimal weight loss to more than a 25% reduction in body weight. https://medicalxpress.com/news/2026-06-tirzepatide-outperformed-semaglutide-weight-loss.html Tue, 16 Jun 2026 16:00:05 EDT news700835336 A major Australian clinical trial has found that timing when you eat can be just as effective as traditional dietitian-led advice in trying to lower the risk of developing type 2 diabetes. https://medicalxpress.com/news/2026-06-simple-window-rival-dietitian-advice.html Tue, 16 Jun 2026 09:20:05 EDT news700818493 A clinical trial supported by the National Institutes of Health (NIH) found that adults with prediabetes assigned to a lifestyle intervention had a significantly lower risk of developing multiple chronic health conditions (known as multimorbidity) over time than those assigned to a placebo. This study, which followed participants for more than two decades, also found that participants assigned to receive metformin did not experience a statistically significant reduction in multimorbidity risk. The findings, published in JAMA, highlight the lasting benefits of lifestyle programs that may lower the risk of developing chronic conditions. https://medicalxpress.com/news/2026-06-adults-prediabetes-lifestyle-intervention-multiple.html Mon, 15 Jun 2026 17:10:01 EDT news700760942 One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-behavioral-modifications-goal-greater-weight.html Mon, 15 Jun 2026 14:50:03 EDT news700733521 Tirzepatide doesn't just help people lose weight; it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-tirzepatide-body-energy-trial.html Mon, 15 Jun 2026 14:50:01 EDT news700722335 Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people ages 50–54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-obesity-rewrites-global-heart-disease.html Mon, 15 Jun 2026 11:20:08 EDT news700737076 Metabolic and bariatric surgery for teens with severe obesity was found to be cost-effective over 10 years, according to a new analysis from Ann & Robert H. Lurie Children's Hospital of Chicago published in JAMA Network Open. While long-term clinical benefits of weight-loss surgery for eligible teens have been well established, and it is recommended by the American Academy of Pediatrics, insurance coverage has been limited and few teens can take advantage of the surgery. https://medicalxpress.com/news/2026-06-economic-case-teen-weight-loss.html Mon, 15 Jun 2026 11:00:14 EDT news700730821 GLP-1 medications are marketed to help you lose weight, but one may be better at it than the rest, according to a new meta-analysis from the University of Georgia. https://medicalxpress.com/news/2026-06-tirzepatide-glp-medication-effective-weight.html Mon, 15 Jun 2026 10:40:01 EDT news700737071 GLP-1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago. In fact, the research team found GLP-1s may improve testosterone levels and sperm quality in men with obesity-related low testosterone, while also addressing the underlying effects of obesity. https://medicalxpress.com/news/2026-06-clinical-trials-glp-1s-fertility.html Mon, 15 Jun 2026 10:00:02 EDT news700482361 Lifestyle-induced loss of visceral fat (and not liver fat, pancreatic fat or subcutaneous fat) may have lasting health benefits years after the end of an intervention, even when body weight is fully regained, according to researchers from Ben-Gurion University of the Negev and their international collaborators. https://medicalxpress.com/news/2026-06-visceral-fat-loss-year-metabolic.html Sun, 14 Jun 2026 15:30:01 EDT news700326228 In people with type 2 diabetes, semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared with other anti-obesity medications, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-semaglutide-linked-bone-fracture.html Sun, 14 Jun 2026 14:50:01 EDT news700464395 Adults with obesity who lost weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-decreases-people-glp-medication.html Sat, 13 Jun 2026 18:40:01 EDT news700464344 Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. https://medicalxpress.com/news/2026-06-testosterone-lifestyle-older-men-diabetes.html Sat, 13 Jun 2026 16:20:01 EDT news700464318 For those scared of needles but who need GLP-1 receptor agonists to help manage their weight, there might be some good news. Researchers are testing a new oral, small-molecule GLP-1 receptor agonist called Elecoglipron, which could offer the weight-loss benefits of GLP-1 therapy without injections. https://medicalxpress.com/news/2026-06-day-pill-weight-loss-phase.html Sat, 13 Jun 2026 11:40:01 EDT news700394634 Once-weekly cagrilintide, an amylin receptor agonist, plus semaglutide is efficacious for adults with type 2 diabetes inadequately controlled with diet and exercise, receiving metformin with or without a sodium glucose cotransporter 2 inhibitor (SGLT2i), and using basal insulin, according to three studies published online June 7 in The Lancet Diabetes & Endocrinology and The Lancet to coincide with the annual meeting of the American Diabetes Association, held from June 5 to 8 in New Orleans. https://medicalxpress.com/news/2026-06-ada-weekly-cagrilintide-semaglutide-diabetes.html Fri, 12 Jun 2026 14:20:04 EDT news700486704 Have you ever wondered why savory foods like chips, nachos and salted nuts go so well with a beer or glass of wine? And why sometimes you feel an insatiable appetite for junk food while drinking? https://medicalxpress.com/news/2026-06-alcohol-chips-nachos.html Fri, 12 Jun 2026 09:40:04 EDT news700474922 Many people cross bread, pasta and potatoes off their menus, hoping to drop pounds and improve their heart health. But there's a controversy behind this multibillion-dollar wellness phenomenon: Research is divided on carbohydrate-restricted diets. https://medicalxpress.com/news/2026-06-consuming-moderate-amount-carbs-cardiovascular.html Thu, 11 Jun 2026 21:00:01 EDT news700389666 Chile's complementary set of policies targeting food products high in fat, salt and sugar plausibly reduces the risk of school-age children being overweight or having obesity, finds a study published in The Lancet. https://medicalxpress.com/news/2026-06-chile-food-ad-child-obesity.html Thu, 11 Jun 2026 18:30:01 EDT news700388102 Hip dips are having a moment. The perfectly normal indentations that sit below your hips on the outer thigh have become the latest body feature to be scrutinized, fixed and agonized over on social media. But what are they? Can you actually get rid of them? And should you even try? https://medicalxpress.com/news/2026-06-hip-dips.html Wed, 10 Jun 2026 20:20:02 EDT news700306705 For adults with obesity without diabetes, once-weekly survodutide, an investigational glucagon receptor-glucagon-like peptide-1 receptor dual agonist, is associated with greater reductions in body weight than placebo, according to a study published online June 7 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 5 to 8 in New Orleans. https://medicalxpress.com/news/2026-06-weekly-survodutide-linked-body-weight.html Wed, 10 Jun 2026 19:40:04 EDT news700324922 Researchers at the University of Colorado Anschutz have published a proof-of-concept study in Fertility and Sterility demonstrating that injectable semaglutide may offer meaningful reproductive benefits for women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS). https://medicalxpress.com/news/2026-06-semaglutide-early-fertility-women-pmos.html Wed, 10 Jun 2026 06:19:29 EDT news700291117 Our brain prepares the body for an incoming meal before we even take the first bite. The aroma of food simmering on the stove, for instance, can trigger the brain to send signals to the pancreas, which in turn releases insulin into the bloodstream. A new Nature Metabolism study reveals how a key group of neurons helps mediate this process. https://medicalxpress.com/news/2026-06-brain-mechanism-reveals-food-aroma.html Tue, 09 Jun 2026 16:40:07 EDT news700234239 Researchers from LSU's Pennington Biomedical Research Center and collaborating institutions have found that Americans with the highest levels of obesity are undergoing fewer surgical procedures overall. These procedures include common operations like knee or hip replacement, hernia surgery, and surgery of the breast, prostate and colon—operations that are frequently done for cancer. https://medicalxpress.com/news/2026-06-americans-severe-obesity-surgeries.html Tue, 09 Jun 2026 15:40:01 EDT news700228021 The American Heart Association and the American College of Cardiology, along with two other leading medical organizations, have developed the first-ever guideline aimed at preventing and managing cardiovascular-kidney-metabolic (CKM) syndrome, an interconnected set of health conditions that significantly increase the risk of multiorgan complications and adverse cardiovascular outcomes. https://medicalxpress.com/news/2026-06-guideline-cardiovascular-kidney-metabolic-syndrome.html Tue, 09 Jun 2026 14:00:06 EDT news700132456