https://medicalxpress.com/ en-us provides the latest news from Wake Forest University Baptist Medical Center Prostate cancer is the second-leading cause of cancer death in men with more than 34,000 deaths in the U.S. each year, according to the American Cancer Society. But guidelines for prostate cancer screening are continually shifting, leading to uncertainty among patients and providers on when and if screening tests should be ordered. https://medicalxpress.com/news/2023-01-prostate-cancer-screening-patients.html Wed, 04 Jan 2023 14:10:55 EST news592063850 The Wake Forest Institute for Regenerative Medicine (WFIRM) researchers, who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells. In their latest published study, they focus on how telomerase activity affects the regenerative potential of these and other types of stem cells. https://phys.org/news/2022-06-human-urine-derived-stem-cells-robust.html Tue, 28 Jun 2022 13:05:50 EDT news575640344 Researchers from Wake Forest University School of Medicine have discovered a possible new approach in treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer. https://medicalxpress.com/news/2022-06-scientists-nanoparticle-solid-tumors.html Tue, 14 Jun 2022 14:44:14 EDT news574436646 A simple blood test to diagnose Alzheimer's disease, perhaps even years before symptoms appear, is an exciting possibility, but a new study shows that much more research is needed before these blood tests are routinely used in the clinical diagnostic setting. https://medicalxpress.com/news/2022-05-comorbidities-plasma-biomarker-alzheimer-disease.html Thu, 26 May 2022 11:52:19 EDT news572784735 When it comes to weight loss, the old adage it's all in your head may be true. https://medicalxpress.com/news/2022-05-brain-networks-role-weight-loss-success.html Tue, 03 May 2022 14:02:40 EDT news570805357 Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases. https://phys.org/news/2022-05-team-method-gene-efficiency-minimizing.html Mon, 02 May 2022 15:48:46 EDT news570725324 Have you ever felt uncomfortable when asked about depression or any other sensitive personal issue when checking in for a medical visit? https://medicalxpress.com/news/2022-03-self-administered-screening-benefits-patients.html Tue, 08 Mar 2022 11:00:04 EST news565952029 Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States. https://medicalxpress.com/news/2022-02-biomarkers-patient-response-immunotherapy-treatment.html Thu, 17 Feb 2022 10:00:01 EST news564299298 Researchers at Wake Forest School of Medicine have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE). MPE is the accumulation of fluid between the chest wall and lungs and is accompanied by malignant cells and/or tumors. https://phys.org/news/2021-12-nanoparticle-therapeutic-cancer-immunotherapy.html Thu, 16 Dec 2021 11:00:03 EST news558860098 For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment. https://medicalxpress.com/news/2021-12-scientists-malfunctioning-brain-cells-potential.html Fri, 10 Dec 2021 11:16:49 EST news558357404 Following the Affordable Care Act (ACA) Medicaid expansion, access to bariatric surgery as a treatment for obesity increased by 31% annually for lower-income Medicaid-covered and uninsured white adults age 26 to 64 but not for Hispanic and Black adults, according to research conducted by scientists at Wake Forest School of Medicine. https://medicalxpress.com/news/2021-10-medicaid-expansion-access-bariatric-surgery.html Fri, 08 Oct 2021 12:32:24 EDT news552915141 Researchers at Wake Forest School of Medicine have shown that a targeted therapy using non-thermal radio waves is safe to use in the treatment of hepatocellular carcinoma (HCC), the most common type of liver cancer. The therapy also showed a benefit in overall survival. https://medicalxpress.com/news/2021-07-radio-wave-therapy-safe-liver-cancer.html Fri, 30 Jul 2021 17:01:50 EDT news546883292 Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people. Immunotherapies, also known as biologic therapies, activate the body's own immune system to control, and eliminate cancer. https://medicalxpress.com/news/2021-07-personalized-immunotherapy-response-body-on-a-chip-cancer.html Mon, 19 Jul 2021 10:02:04 EDT news545907714 Answering a charge from the National Science Board, the RegenMed Development Organization (ReMDO), through its RegeneratOR Workforce Development Initiative, has released the results of a national survey of regenerative medicine biomanufacturing knowledge, skills, and abilities needed for successful employment in the regenerative medicine field. https://medicalxpress.com/news/2021-07-national-survey-ids-gaps-opportunities.html Fri, 16 Jul 2021 03:34:30 EDT news545625266 With preseason football training on the horizon, a new study shows that head impacts experienced during practice are associated with changes in brain imaging of young players over multiple seasons. https://medicalxpress.com/news/2021-06-association-impacts-imaging-youth-football.html Tue, 15 Jun 2021 00:00:01 EDT news542903749 When people think of microbiome, they typically think about the gut, but there's also a breast microbiome, and the role it plays in breast health and breast cancer isn't thoroughly understood. A microbiome is the collection of microorganisms that live in a particular environment in the body. https://medicalxpress.com/news/2021-06-evidence-diet-microbiome-affect-breast.html Thu, 03 Jun 2021 12:48:38 EDT news541943312 Heart failure (HF) - when the heart can't pump enough blood and oxygen through the body—affects approximately 6.2 million adults in the United States and is the primary cause of hospitalization in the elderly. Unfortunately, older adults with heart failure often have poor outcomes resulting in reduced quality of life, high mortality and frequent rehospitalizations. https://medicalxpress.com/news/2021-05-rehab-outcome-older-heart-failure-patients.html Sun, 16 May 2021 16:49:48 EDT news540402582 An intestinal bowel disease that affects up to 10 percent of premature infants at a very vulnerable and developmentally crucial time can lead to serious infection and death. Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) are tackling the disease with a human placental-derived stem cell (hPSC) therapy strategy that is showing promising results. https://medicalxpress.com/news/2021-04-stem-cell-therapy-potential-intestinal.html Tue, 27 Apr 2021 13:16:06 EDT news538748162 Investigators at Wake Forest School of Medicine, part of Wake Forest Baptist Health, have identified a set of new genetic markers that could potentially lead to new personalized treatments for lung cancer. https://medicalxpress.com/news/2021-04-genetic-markers-lung-cancer.html Wed, 14 Apr 2021 10:25:18 EDT news537614715 According to the American Cancer Society, a noninvasive breast cancer called ductal carcinoma in situ (DCIS) accounts for approximately one of every four new breast cancer cases in the United States. If left untreated, DCIS has the potential to evolve into invasive cancer, so many patients choose to have breast-conserving surgery or mastectomy after a diagnosis. https://medicalxpress.com/news/2021-04-surgical-technique-positive-margin-breast.html Mon, 05 Apr 2021 12:45:43 EDT news536845541 The fear, anxiety and stress associated with the COVID-19 pandemic has taken a toll on mental health. But a new study suggests these symptoms may be alleviated through safe and convenient online mindfulness practices. https://medicalxpress.com/news/2021-03-online-mindfulness-mental-health-covid-.html Tue, 23 Mar 2021 11:42:39 EDT news535718556 The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans. https://medicalxpress.com/news/2021-03-cat-chronic-kidney-disease.html Fri, 12 Mar 2021 12:38:12 EST news534775087 For people who are overweight or obese and have type 2 diabetes, the first line of treatment is usually lifestyle intervention, including weight loss and increased physical activity. While this approach has cardiovascular benefit for many, it can be detrimental for people who have poor blood sugar control, according to a study conducted by researchers at Wake Forest School of Medicine. https://medicalxpress.com/news/2021-03-lifestyle-intervention-beneficial-people-diabetes.html Thu, 11 Mar 2021 10:25:55 EST news534680752 There is a growing recognition in health care that social factors such as racial bias, access to care and housing and food insecurity, have a significant impact on people's health. Compounding and amplifying those underlying inequalities are the ongoing disruptions related to the COVID-19 pandemic and social unrest in our country. https://medicalxpress.com/news/2021-03-medical-school-curriculum-aim-social.html Mon, 01 Mar 2021 11:00:05 EST news533802424 Breast cancer is the second most common cancer among women in the United States, and cigarette smoking is associated with a higher incidence of breast cancer spread, or metastasis, lowering the survival rate by 33% at diagnosis. https://medicalxpress.com/news/2021-01-scientists-link-nicotine-breast-cancer.html Thu, 21 Jan 2021 13:01:12 EST news530456469 Most doctors would agree that advanced care planning (ACP) for patients, especially older adults, is important in providing the best and most appropriate health care over the course of a patient's life. https://medicalxpress.com/news/2021-01-nurse-involvement-discussion-advanced-office.html Mon, 11 Jan 2021 11:00:09 EST news529567203 Migraine is a neurological disease that can be severely debilitating and is the second leading cause of disability worldwide. Unfortunately, many patients with migraine discontinue medications due to ineffectiveness or side effects. Many patients still use opioids despite recommendations against them for headache treatment. However, in a recent clinical trial from Wake Forest Baptist Health, researchers showed that mindfulness-based stress reduction (MBSR) may provide benefit to people with migraine. https://medicalxpress.com/news/2020-12-mindfulness-meditation-decrease-impact-migraine.html Mon, 14 Dec 2020 11:00:06 EST news527165248 Even before the pandemic and the presidential election, Americans reported some of the highest perceived levels of stress in the world, according to the American Psychological Association. Not only does stress have negative effects on work and personal relationships, it also increases the risk of many chronic conditions, such as heart disease and Alzheimer's disease, and is associated with higher mortality rates. https://medicalxpress.com/news/2020-11-mediterranean-diet-effects-stress-animal.html Mon, 16 Nov 2020 12:54:00 EST news524753637 Wake Forest Institute for Regenerative Medicine scientists (WFIRM) have developed a method to bioprint a type of cartilage that could someday help restore knee function damaged by arthritis or injury. https://phys.org/news/2020-11-scientists-hybrid-tissue-cartilage-regeneration.html Mon, 09 Nov 2020 03:09:02 EST news524113724 Scientists at Wake Forest School of Medicine have recorded real time changes in dopamine and serotonin levels in the human brain that are involved with perception and decision-making. These same neurochemicals also are critical to movement disorders and psychiatric conditions, including substance abuse and depression. https://medicalxpress.com/news/2020-10-scientists-role-dopamine-serotonin-human.html Mon, 12 Oct 2020 11:10:01 EDT news521718504