https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. In the brain, information travels among distributed networks, groups of interconnected regions that work together and contribute to specific behaviors, feelings or thoughts. To study how information travels through these networks under different conditions, many neuroscientists rely on functional magnetic resonance imaging (fMRI), a noninvasive imaging technique that measures blood-oxygen changes indirectly linked to neural activity. https://medicalxpress.com/news/2026-09-brain-framework-reveals-shifts-pain.html Tue, 22 Sep 2026 06:20:01 EDT news709207805 Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms? https://medicalxpress.com/news/2026-09-autism-mutations-reveal-opposing-patterns.html Thu, 17 Sep 2026 16:20:07 EDT news708879661 A newly proposed International Association for the Study of Lung Cancer (IASLC) tumor budding–based grading system successfully identified patients with resected lung squamous cell carcinoma (SqCC) at higher risk of poor outcomes and showed potential to help guide selection for adjuvant chemotherapy, according to research presented at the IASLC 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-iaslc-tumor-budding-grade-high.html Tue, 15 Sep 2026 20:20:01 EDT news708684006 An exploratory 8-year landmark update from the Phase III ADAURA trial showed that adjuvant osimertinib continued to provide a long-term overall survival benefit for patients with completely resected, EGFR-mutated stage IB–IIIA non-small cell lung cancer (NSCLC). The findings were presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-sustained-survival-benefit-adjuvant-osimertinib.html Sun, 13 Sep 2026 21:50:06 EDT news708350701 The investigational combination of pumitamig and elfetabart drozuntecan (elfe-D) demonstrated a manageable safety profile and encouraging early antitumor activity in patients with small cell lung cancer (SCLC), according to first clinical data from the ongoing Phase Ib/II BNT324-01 trial presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC). https://medicalxpress.com/news/2026-09-pumitamig-ifinatamab-deruxtecan-early-small.html Sat, 12 Sep 2026 05:20:05 EDT news708248108 University of Warwick researchers have analyzed data from more than 1.9 million people across 23 studies and found that ADHD is linked to an almost 50% increase in overall gastrointestinal symptoms compared with people without ADHD. The association was even stronger for specific problems: nearly double the odds of constipation, a 58% increase in irritable bowel syndrome, and more than four times the odds of encopresis (loss of bowel control). https://medicalxpress.com/news/2026-09-people-adhd-gut-problems-major.html Thu, 10 Sep 2026 19:10:01 EDT news708257581 A new study by investigators at Cedars-Sinai Health Sciences University has identified differences in the makeup and organization of the small bowel microbiome between women and men. The findings, published in iScience, could offer new insights into why some conditions are more prevalent in women. https://medicalxpress.com/news/2026-09-small-bowel-microbiome-clues-women.html Mon, 07 Sep 2026 15:20:08 EDT news708009843 Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement. One bacterial signal helps set the intestines in motion, while another primes gut cells to respond more strongly, amplifying the effect. The research expands scientists' understanding of how the gut microbiome communicates with the body, moving beyond the traditional focus on individual bacteria or bacterial molecules. https://medicalxpress.com/news/2026-08-scientists-uncover-microbiome-paths-ibs.html Mon, 31 Aug 2026 12:40:07 EDT news707395262 Atherosclerosis, the process underlying most cardiovascular diseases, begins long before the first symptoms appear. An international study shows that the disease can already be detected in apparently healthy young adults and is much more common than previously thought. https://medicalxpress.com/news/2026-08-silent-artery-plaques-adults-age.html Sat, 29 Aug 2026 03:00:02 EDT news707132041 What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer's pathologies may be orchestrated by a molecular switch called ERBB4 when it turns on in the wrong neurons. Once activated, this misplaced signal can set off a chain reaction that disrupts brain circuits, eliminates synapses, activates glial cells, increases amyloid pathology and impairs memory. https://medicalxpress.com/news/2026-08-rogue-neuronal-root-alzheimer-disease.html Wed, 26 Aug 2026 14:20:05 EDT news706967991 A collaborative clinical study led by National Taiwan University Hospital (NTUH) and Taiwan Clinical Oncology Group, National Health Research Institutes (TCOG, NHRI) has yielded promising results for a new therapeutic regimen to treat primary central nervous system lymphoma (PCNSL), a rare and aggressive cancer that develops in the brain or other parts of the central nervous system. https://medicalxpress.com/news/2026-08-drug-treatment-regimen-difficult-brain.html Wed, 26 Aug 2026 11:40:02 EDT news706956042 Fewer cases of mpox virus (MPXV) infection were reported in 2025 than in 2024, but the number of reported cases during September to October 2025 was double that seen in 2024, according to research published in the Aug. 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. https://medicalxpress.com/news/2026-08-cdc-characterizes-epidemiology-mpox-infection.html Mon, 24 Aug 2026 15:40:01 EDT news706797205 Patients with irritable bowel syndrome (IBS) have an increased risk of incident psoriasis, according to a study published online Aug. 7 in the Journal of Global Health. https://medicalxpress.com/news/2026-08-term-incident-psoriasis-elevated-bowel.html Tue, 18 Aug 2026 14:40:01 EDT news706275508 Puberty is a process regulated by the endocrine system, and its timing can be altered by environmental factors. Several recent studies point to a trend toward earlier onset of puberty in girls, a phenomenon linked to a complex interplay among genetics, lifestyle and exposure to chemicals capable of interfering with hormones. Among these substances are certain pesticides, widely used in agriculture and present in some everyday foods. https://medicalxpress.com/news/2026-07-links-exposure-fungicides-insecticides-age.html Fri, 31 Jul 2026 13:00:02 EDT news704720762 Yoga is best known for improving flexibility, building strength and reducing stress. Research suggests it may also help ease symptoms of irritable bowel syndrome (IBS), a common digestive disorder that affects millions of people. https://medicalxpress.com/news/2026-07-yoga-relieve-bowel-syndrome-symptoms.html Thu, 30 Jul 2026 08:00:06 EDT news704613961 A study led by investigators at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) suggests that intensive cardiac surveillance programs routinely used for lymphoma patients with low to moderate cardiovascular risk who are treated with anthracyclines may have limited clinical value. https://medicalxpress.com/news/2026-07-intensive-cardiac-surveillance-cancer-patients.html Wed, 29 Jul 2026 15:20:04 EDT news704550805 The brain continuously produces metabolic waste that must be removed to maintain healthy function. Cerebrospinal fluid (CSF) plays a central role in this process by carrying away proteins such as amyloid-β, phosphorylated tau and α-synuclein, which are linked to Alzheimer's disease, Parkinson's disease and other neurodegenerative disorders when they accumulate abnormally. https://medicalxpress.com/news/2026-07-scientists-hidden-gateways-brain.html Wed, 22 Jul 2026 11:40:01 EDT news703938817 Dozens of research teams around the world are working to halt, treat and even prevent Alzheimer's disease, which silently develops in the brain for more than a decade before symptoms appear. Although recent years have brought important advances, researchers continue to search for therapies that can more effectively alter the course of Alzheimer's and other forms of dementia. https://medicalxpress.com/news/2026-07-immune-therapy-alzheimer-phase-trial.html Thu, 16 Jul 2026 07:20:04 EDT news703403060 Irritable bowel syndrome (IBS) is a common condition that affects more than 10% of the general population, causing recurrent abdominal pain, bloating, constipation and diarrhea. IBS is considered a disorder of gut-brain interaction, and previous research, including genetic research, has established links to nerve signaling, the nervous system and other conditions including anxiety and mood disorders. The exact biological mechanisms, however, have remained frustratingly difficult to pin down, leaving many patients without effective, targeted treatments. https://medicalxpress.com/news/2026-07-genetic-links-ibs-lipid-metabolism.html Thu, 09 Jul 2026 09:00:01 EDT news702712300 An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented at the ISSCR 2026 Annual Meeting. The Phase Ib/IIa REGEN4HD study represents a significant translational milestone following years of preclinical research, pivotal safety studies, regulatory engagement and clinical trial development. https://medicalxpress.com/news/2026-07-huntington-treatment-quest-pluripotent-stem.html Thu, 09 Jul 2026 08:30:14 EDT news702720929 Some memories remain with us for years, shaping how we learn from experience and adapt to the world around us. Others disappear quickly, even when they once seemed important. Although scientists have long studied how memories are formed in the brain, far less is known about what allows certain memories to persist over time. https://medicalxpress.com/news/2026-07-astrocytes-memories-weeks-stabilizing-neural.html Tue, 07 Jul 2026 12:00:02 EDT news702639053 A team of scientists from the University of Granada (UGR), the Granada Institute for Biomedical Research (ibs.GRANADA), the Public University of Navarra and the Biomedical Research Networking Center (CIBER) has demonstrated that limiting food intake to an eight-hour window helps maintain weight loss 12 months after the end of the intervention in overweight or obese adults. https://medicalxpress.com/news/2026-07-intermittent-fasting-term-weight-loss.html Fri, 03 Jul 2026 08:20:06 EDT news702210327 An early clinical study shows that a new oral drug is safe and well tolerated in patients with chronic heart failure. The study, led by researchers at Karolinska Institutet, has been published in The Lancet. https://medicalxpress.com/news/2026-06-oral-heart-failure-drug-safe.html Thu, 25 Jun 2026 14:20:07 EDT news701609295 Irritable bowel syndrome (IBS) is a condition characterized by abdominal pain, bloating and changes in bowel movements, estimated to affect between 10% and 15% of people worldwide. Past studies suggest that in many cases this condition is accompanied by anxiety, an emotional state marked by worry, fear and/or overthinking about specific life events. https://medicalxpress.com/news/2026-06-species-gut-bacteria-ease-anxiety.html Thu, 25 Jun 2026 08:00:02 EDT news701522887 The Division of Gastroenterology and Hepatology at Feinberg has a distinct strength in understanding how behavior and lifestyle influence gastrointestinal (GI) health. Through its work and in collaboration with the Northwestern Medicine Digestive Health Center, the division conducts research aimed at improving treatments for disorders of the digestive tract and related organs. https://medicalxpress.com/news/2026-06-evidence-behavioral-interventions-gastroenterology.html Tue, 16 Jun 2026 08:20:04 EDT news700809541 Chile's complementary set of policies targeting food products high in fat, salt and sugar plausibly reduces the risk of school-age children being overweight or having obesity, finds a study published in The Lancet. https://medicalxpress.com/news/2026-06-chile-food-ad-child-obesity.html Thu, 11 Jun 2026 18:30:01 EDT news700388102 Millions of people worldwide are periodically or chronically affected by gut-related conditions, such as irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and gastroenteritis. Uncovering the physiological and biological processes that contribute to gut health could thus be highly valuable, as it might help devise more effective interventions to prevent and treat these ailments. https://medicalxpress.com/news/2026-06-gut-microbes-hormone-movement.html Thu, 11 Jun 2026 11:20:08 EDT news700394620 Researchers have identified a promising new therapeutic strategy for autism spectrum disorder (ASD). A research team led by Director KIM Eunjoon of the IBS Center for Synaptic Brain Dysfunctions has now identified a promising new strategy for restoring NMDA receptor (NMDAR) function by targeting a glycine transporter called Slc6a20a/SLC6A20. https://medicalxpress.com/news/2026-06-therapy-reverse-autism-brain-deficits.html Tue, 09 Jun 2026 11:20:01 EDT news700222501 Flatulence, or farting, is something people often joke about or find embarrassing when it happens unexpectedly. It is, however, an essential bodily function that allows the digestive system to keep pressure within the intestinal tract low and prevents painful stretching of the stomach and intestines. Even though it is normal to fart, it remains unclear what counts as a healthy number. https://medicalxpress.com/news/2026-06-people-gas-app.html Mon, 08 Jun 2026 10:00:05 EDT news700130400 Researchers at the Icahn School of Medicine at Mount Sinai have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection. https://medicalxpress.com/news/2026-06-gut-bacteria-fecal-transplants-small.html Tue, 02 Jun 2026 13:20:01 EDT news699619981