https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell. https://medicalxpress.com/news/2025-01-viral-protein-nef-enables-shelf.html Fri, 31 Jan 2025 03:20:46 EST news657516039 An accelerated course of radiation therapy does not increase complications for patients who undergo breast reconstruction following a mastectomy, new research shows. Findings of the large, Phase III RT CHARM trial (Alliance A221505) were presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting. https://medicalxpress.com/news/2024-09-mastectomy-therapy-shortened-patients-breast.html Mon, 30 Sep 2024 10:00:01 EDT news646643844 For women undergoing autologous breast reconstruction—reconstruction using the patient's own tissues, rather than implants—the risks of overall and specific complications are increased at higher body mass index (BMI) levels, a research team reports in Plastic and Reconstructive Surgery. https://medicalxpress.com/news/2024-03-higher-body-mass-index-linked.html Thu, 07 Mar 2024 17:06:03 EST news629053561 Women undergoing autologous breast reconstruction—in which the breast is reconstructed using the patient's own tissues—report higher satisfaction with their breasts at follow-up, compared to those undergoing implant-based reconstruction, reports a study in a special October supplement to Plastic & Reconstructive Surgery. https://medicalxpress.com/news/2023-09-patients-higher-satisfaction-breast-reconstruction.html Thu, 28 Sep 2023 16:17:59 EDT news615136673 Trial results presented today revealed a promising therapy for patients experiencing angina due to coronary microvascular dysfunction (CMD). The results of the study were presented today as feature clinical research during the SCAI 2020 Scientific Sessions Virtual Conference. https://medicalxpress.com/news/2020-05-cell-therapy-treatment-cardiac-patients.html Thu, 14 May 2020 15:43:14 EDT news508689783 It will soon be a year since Jessica Starr, a popular weather person on Detroit TV, took her own life. Her husband said she did so because of complications related to her recent laser refractive surgery. https://medicalxpress.com/news/2020-02-laser-surgery-nightmare-toll-enormous.html Thu, 13 Feb 2020 09:10:01 EST news500807297 Researchers have designed a safer, faster and cheaper cell-based regenerative therapy approach for the treatment of one of the most common human dental diseases, namely periodontitis. A destructive and painful condition that is marked by inflammation and subsequent loss of the gums and the supporting structures of the teeth, periodontitis is caused by bacteria that trigger inflammation of the gums that surround teeth. The proposed therapy design promises to address periodontitis without the shortcomings and limitations of regenerative therapies to date. By safely and effectively addressing one of the most common human diseases in both a time- and cost- efficient manner, the novel therapy represents monumental advantages to public health. https://medicalxpress.com/news/2019-05-treatment-periodontitis-gum-regeneration.html Fri, 10 May 2019 09:23:16 EDT news476698989 A growing need for tissues and organs in surgical reconstruction is addressed by the promising field of tissue engineering. For instance, muscle atrophy results from severe traumatic events including deep burns and cancer, requiring site/donor compatible surgical reconstruction. The existing 'gold standard' treatment in reconstructive surgery incorporates autologous flaps, although the technique is limited by low anatomical availability and donor site morbidity during clinical transplantation. As a clinically favorable alternative, tissue engineering presents strategies to engineer tissue grafts with improved quality and effectiveness. To maintain the viability of implants upon transplantation, increasing efforts are invested in designing pre-vascularized engineered tissue. Design examples include a multicellular culture of endothelial, mural and tissue-specific cells for self-assembly of vessel networks and cellular co-culture to build lasting, stable blood vessels to induce neovascularization within the host. https://medicalxpress.com/news/2018-10-genetically-d-human-muscle-transplant.html Wed, 10 Oct 2018 09:30:01 EDT news458377291 A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial. The study can be found in the open access journal Protein & Cell. https://medicalxpress.com/news/2018-02-lung-stem-cell-transplantation-clinical.html Fri, 09 Feb 2018 10:40:32 EST news437395219 Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients' own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18-55 years) whose cartilage was damaged by injury. Two years after reconstruction, most recipients reported improvements in pain, knee function, and quality of life, as well as developing repair tissue that is similar in composition to native cartilage. https://medicalxpress.com/news/2016-10-swiss-doctors-success-cells-nose.html Fri, 21 Oct 2016 02:00:01 EDT news396233748 Genetic research is a key to understanding how either race or ethnicity affect the incidence of different cancers and how these factors may contribute to different responses to the same treatments. Multiple myeloma, a blood cancer of the immune system's plasma cells, occurs two to three times more often in African Americans than in Caucasians. Finding out why could lead to better therapies for all. Winship Cancer Institute researchers couldn't do it without people like Veronica Reynolds. https://medicalxpress.com/news/2015-07-blood-cancer-african-americans-therapies.html Wed, 15 Jul 2015 05:48:44 EDT news356158115 (HealthDay)—Complications are rare among breast cancer patients who undergo mastectomy and reconstruction, a new study indicates. https://medicalxpress.com/news/2014-09-complication-mastectomy-breast-reconstruction.html Tue, 02 Sep 2014 18:30:01 EDT news328898805 Among patients with a severe, life-threatening type of sclerosis, treatment with hematopoietic stem cell transplantation (HSCT), compared to intravenous infusion of the chemotherapeutic drug cyclophosphamide, was associated with an increased treatment-related risk of death in the first year, but better long-term survival, according to a study in the June 25 issue of JAMA. https://medicalxpress.com/news/2014-06-stem-cell-transplantation-severe-sclerosis.html Tue, 24 Jun 2014 16:13:19 EDT news322845156 Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement in left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each contraction) after 4 months in patients with chronic postinfarction heart failure, according to a study in the April 17 issue of JAMA. The results, which require confirmation in larger trials, demonstrate the potential for this type of therapy to reduce adverse clinical events in these chronically ill patients. https://medicalxpress.com/news/2013-04-outcomes-heart-failure-cell-therapy.html Tue, 16 Apr 2013 16:39:51 EDT news285349182 (HealthDay) -- Claims data can be used to accurately identify rates and risk factors for surgical site infection (SSI) following spinal surgery, according to a study published in the July 1 issue of Spine. https://medicalxpress.com/news/2012-07-reveals-patients-post-op-infection.html Fri, 13 Jul 2012 18:40:01 EDT news261419494 Results from a Cedars-Sinai Heart Institute clinical trial show that treating heart attack patients with an infusion of their own heart-derived cells helps damaged hearts re-grow healthy muscle. https://medicalxpress.com/news/2012-02-first-of-its-kind-stem-cell-re-grows-healthy.html Mon, 13 Feb 2012 18:30:01 EST news248371179 The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs. https://medicalxpress.com/news/2011-11-world-stem-cell-bandage-human.html Mon, 14 Nov 2011 10:25:47 EST news240488737 Surgeons should encourage men who request penile lengthening surgery to try non-invasive methods first and, in some cases, consider therapy to help them feel more positive about their body. https://medicalxpress.com/news/2011-04-noninvasive-surgery-men-longer-penis.html Mon, 18 Apr 2011 09:33:32 EDT news222337999