https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. T cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infections. Now scientists at La Jolla Institute for Immunology (LJI) have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. https://medicalxpress.com/news/2026-06-cells-key-measles-virus-deadly.html Tue, 02 Jun 2026 11:00:01 EDT news699525961 A new study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center shows that the targeted cancer drug selpercatinib can significantly reduce the risk of lung cancer returning in patients with a rare genetic subtype of early-stage non-small cell lung cancer (NSCLC), potentially offering a new treatment option to help keep the disease from coming back after standard therapy. https://medicalxpress.com/news/2026-06-therapy-lung-cancer-recurrence-rare.html Mon, 01 Jun 2026 17:10:01 EDT news699550802 Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods—and these organoids grow their own nerve cells. https://medicalxpress.com/news/2026-05-3d-trays-human-gut-organoids.html Fri, 22 May 2026 13:00:03 EDT news698673181 In April 2026, a passenger boarded a Dutch cruise ship in Ushuaia, Argentina after a bird-watching trip. Ten days later, he died. The cause of his death, while initially unclear, was determined to be Andes hantavirus (ANDV), which he picked up prior to boarding the ship. His wife, sickened by the same virus, later died as well. https://medicalxpress.com/news/2026-05-andes-hantavirus-people.html Fri, 22 May 2026 07:40:01 EDT news698646901 Specific genetic fusion patterns in solitary fibrous tumors may help identify which patients face a higher risk of metastasis, recurrence and more aggressive disease behavior, according to new research that could improve how physicians assess and eventually treat this rare cancer. https://medicalxpress.com/news/2026-05-genetic-clues-reveal-rare-solitary.html Fri, 22 May 2026 07:00:02 EDT news698642582 Why do cells age—and why do we lose our energy and vitality as we get older? This question is one of the central challenges of modern biomedicine. The focus is particularly on mitochondria—tiny cellular organelles long known as the cell's powerhouses but now understood as dynamic control centers that not only produce energy, but also coordinate cellular communication, adaptation, and many of the processes essential for life. https://medicalxpress.com/news/2026-05-energy-age-membrane-lipid-destabilize.html Thu, 21 May 2026 16:20:05 EDT news698587261 The resignation of Marty Makary, commissioner of the U.S. Food and Drug Administration, on May 12, 2026, brought to the forefront a heated controversy over fruit-flavored nicotine vapes. https://medicalxpress.com/news/2026-05-flavored-vapes-major-shakeup-fda.html Mon, 18 May 2026 13:40:03 EDT news698326682 Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms. The tool, detailed in an article published in The Journal of Molecular Diagnostics, enables a higher diagnostic yield from low-coverage, low-cost sequencing. https://medicalxpress.com/news/2026-05-tool-enables-high-precision-pediatric.html Thu, 14 May 2026 17:00:01 EDT news697972128 Developing effective immunotherapies for acute myeloid leukemia (AML) has long been hampered by a critical challenge: Therapy directed at killing the leukemia cells may also harm the body's ability to make new, healthy blood cells. This happens because most of the proteins that can be targeted on the surface of the blood cancer's cells are also found on vital blood-forming cells. https://medicalxpress.com/news/2026-05-successfully-acute-myeloid-leukemia-patients.html Tue, 12 May 2026 19:00:01 EDT news697821361 Most prostate cancers rely on male sex hormones, known as androgens, to grow. As a result, standard treatment focuses on lowering androgen levels or blocking their activity, but many tumors eventually become resistant and the disease returns. https://medicalxpress.com/news/2026-05-molecular-marker-prostate-cancer-treatment.html Tue, 12 May 2026 15:20:04 EDT news697814522 The U.S. Food and Drug Administration (FDA) has approved Bizengri to treat an ultra-rare, aggressive cancer that forms in the bile ducts. https://medicalxpress.com/news/2026-05-fda-green-bizengri-drug-rare.html Mon, 11 May 2026 17:20:09 EDT news697729095 Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of neutralizing measles virus. These antibodies bind to key sites on measles virus and prevent the virus from entering host cells. The new panel of human antibodies may form the basis for future medical therapies against measles infection. In the study, an infusion of these antibodies resulted in a 500-fold lower viral load in a rodent model of measles infection. https://medicalxpress.com/news/2026-05-scientists-crucial-world-measles-treatment.html Thu, 07 May 2026 11:00:11 EDT news697276141 Research conducted at the National Cancer Research Centre (CNIO) has revealed an unexpected behavior observed in a protein involved in several types of cancer: it manages to self-activate, meaning it gives itself the order to start working in the cell. This finding shows that its activation process is accelerated, making it much faster than in normal proteins. https://medicalxpress.com/news/2026-04-revealing-unusual-ability-protein-involved.html Wed, 29 Apr 2026 19:40:07 EDT news696699001 In patients with myasthenia gravis, the surgical removal of the thymus gland, called thymectomy, added "quality adjusted life years" to patients and was also cost-effective in comparison to pharmacological treatment alone, according to a study published April 13 in JAMA Network Open. "Quality adjusted life years" are a measure used in health economics to represent how much a drug or intervention extends and improves one's quality of life. https://medicalxpress.com/news/2026-04-myasthenia-gravis-surgical-thymus-gland.html Fri, 24 Apr 2026 13:00:04 EDT news696248941 Researchers at the University of British Columbia Faculty of Medicine have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells—showing strong results in preclinical studies that bring the breakthrough closer to human clinical trials. The therapy targets a protein called IL1RAP, which is found on the surface of certain cancer cells, but is largely absent from normal tissues. By linking a cancer-killing drug to an antibody that recognizes this protein, the team created an antibody-drug conjugate that delivers treatment directly to cancer cells while sparing healthy tissues. https://medicalxpress.com/news/2026-04-therapy-aggressive-childhood-adult-cancers.html Thu, 23 Apr 2026 15:20:01 EDT news696174541 A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona provides one of the clearest roadmaps to date for understanding and treating liver cancer, one of the deadliest cancers worldwide. Published in Cell, the study, "Hallmarks of Liver Cancer: Therapeutic Implications", applies the widely used "Hallmarks of Cancer" framework to liver tumors, linking the biology of the disease to treatment strategies, including immunotherapy and precision medicine approaches, particularly in the approximately 45% of bile duct cancers that harbor targetable mutations. https://medicalxpress.com/news/2026-04-liver-cancer-roadmap-links-tumor.html Thu, 16 Apr 2026 16:40:02 EDT news695572900 Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have developed MitoCatch, a system that enables targeted delivery of healthy mitochondria to specific cell types affected by disease. This innovation is a major step toward precision mitochondrial therapy. https://medicalxpress.com/news/2026-04-mitocatch-healthy-mitochondria-diseased-cells.html Wed, 15 Apr 2026 11:00:07 EDT news695394961 Nearly 10,000 cases of advanced bowel cancer are diagnosed in England each year, with cases in young adults rising. There are limited options for treating advanced bowel cancer. Scientists have now developed an AI-powered method that could determine which patients with advanced bowel cancer are most likely to respond to a targeted drug used on the NHS—potentially sparing thousands of patients from treatments that won't work for them. https://medicalxpress.com/news/2026-04-patients-bowel-cancer-treatment.html Tue, 14 Apr 2026 16:20:03 EDT news695395972 A study using tiny retinas grown in a lab has revealed how subtle changes in a key growth-controlling protein can lead to a condition causing serious eye defects from birth. The findings, published in the journal Biochimica et Biophysica Acta (BBA)—Molecular Basis of Disease, shed new light on ocular coloboma, a rare congenital eye condition affecting about 1 in 5,000 births and responsible for roughly 10% of childhood blindness. Coloboma arises when a structure in the developing eye, the optic fissure, fails to close properly and often co-occurs with other tissue-fusion problems such as cleft lip and/or palate. https://medicalxpress.com/news/2026-04-lab-grown-retina-gene-clue.html Mon, 13 Apr 2026 20:00:04 EDT news695290418 Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) and other partner institutions of the German Center for Diabetes Research (DZD) have now identified a previously unknown function of the PICALM protein in skeletal muscle: The protein responds sensitively to physical activity and intermittent fasting. It also plays a decisive role in the formation of new muscle fibers. https://medicalxpress.com/news/2026-04-picalm-links-intermittent-fasting-muscle.html Mon, 13 Apr 2026 19:00:07 EDT news695309161 Scientists in China have developed a two-antibody cocktail to treat respiratory syncytial virus, or RSV, that in laboratory studies prevented the virus from developing drug resistance—a persistent problem with current therapies for infants. RSV is a seasonal infection that circulates globally and can be especially dangerous for people at opposite ends of the age spectrum: infants and older adults. Vaccines are available for those who are 65 and older (GlaxoSmithKline's Arexvy, Pfizer's ABRYSVO and Moderna's mRESVIA), but there is still no available vaccine for infants who are among the most vulnerable. https://medicalxpress.com/news/2026-04-rsv-evolves-twopronged-antibody-cocktail.html Sun, 12 Apr 2026 14:00:01 EDT news694862856 A research team led by the Fisabio Foundation has demonstrated that dermcidin, an antimicrobial peptide produced constitutively by the human body, also exhibits antiviral activity against the influenza virus. The study also shows that people who do not develop flu-like symptoms have higher baseline levels of this molecule, which could be associated with lower susceptibility to infection. The findings are published in the journal Proceedings of the National Academy of Sciences. https://medicalxpress.com/news/2026-03-natural-molecule-human-body-flu.html Sun, 05 Apr 2026 16:00:05 EDT news694105203 In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth. In a phase 1/2 clinical study with a 42-month-long follow-up period, researchers from Mass General Brigham Cancer Institute recently evaluated the long-term efficacy and safety of the FDA-approved drug pralsetinib, which targets RET. Investigators found that treatment led to durable responses with manageable safety profiles in 281 patients with advanced or metastatic RET fusion-positive NSCLCs. Results are published in the Journal of Clinical Oncology. https://medicalxpress.com/news/2026-04-therapy-term-outcomes-patients-rare.html Wed, 01 Apr 2026 17:20:06 EDT news694274718 In a paper published in the Journal of Clinical Investigation, a research team at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health reports developing a therapeutic intranasal (nose-delivered) DNA vaccine against tuberculosis (TB) that fuses two genes with the goal of directing the immune system to fight drug-tolerant bacterial "persisters" that can survive prolonged antibiotic therapy and contribute to disease relapse. https://medicalxpress.com/news/2026-04-therapeutic-nasally-dna-vaccine-fuses.html Wed, 01 Apr 2026 16:40:07 EDT news694274041 A research team from the Department of Orthopedics and Traumatology, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed), has developed a titanium implant surface that can be activated by near-infrared (NIR). With just 15 minutes of NIR irradiation, this surface can eliminate 99.94% of Staphylococcus aureus (S. aureus) biofilms without the use of antibiotics, while simultaneously promoting bone-implant fusion. https://medicalxpress.com/news/2026-04-smart-titanium-implant-enables-rapid.html Wed, 01 Apr 2026 13:00:01 EDT news694264081 A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor. The findings suggest potential new approaches to treat these aggressive and chemo-resistant tumors. https://medicalxpress.com/news/2026-03-zr-fusion-protein-sways-brain.html Wed, 25 Mar 2026 12:00:43 EDT news693658802 Despite a host of checks and balances that usually prevent harmful genetic mutations, sometimes mistakes happen, with serious consequences. Now, researchers from Japan elucidate how a common mutation underlying a common childhood cancer also makes it highly treatable. https://medicalxpress.com/news/2026-03-infant-leukemia-nutm1-gene-rearrangements.html Wed, 25 Mar 2026 10:40:05 EDT news693652981 A rare form of leukemia known as TCF3::HLF-positive B cell acute lymphoblastic leukemia (B-ALL) sits among the most aggressive blood cancers seen in children. The disease causes a rapid buildup of abnormal blood cells, but unlike other types of leukemia, it also severely damages bones and causes pain. To make things worse, patients with TCF3::HLF-positive B-ALL tend to relapse quickly after treatment, with survival rates remaining low. https://medicalxpress.com/news/2026-03-inflammation-bone-loss-aggressive-childhood.html Tue, 24 Mar 2026 18:00:03 EDT news693582587 Melanoma remains one of the hardest skin cancers to diagnose because it often mimics harmless moles or lesions. While most artificial intelligence (AI) tools rely on dermoscopic images alone, they often overlook crucial patient information (like age, gender, or where on the body the lesion appears) that can improve diagnostic accuracy. This highlights the importance of multimodal fusion models that can enable high precision diagnosis. https://medicalxpress.com/news/2025-11-deep-skin-cancer-accuracy.html Fri, 14 Nov 2025 12:33:04 EST news682345981 About 4,700 bottles of Bariatric Fusion iron-containing multivitamins have been recalled because packaging does not meet federal safety standards, according to the U.S. Consumer Product Safety Commission (CPSC). https://medicalxpress.com/news/2025-09-recall-bariatric-fusion-vitamins-child.html Mon, 15 Sep 2025 14:00:01 EDT news677161452