https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies. The findings, published in Stem Cell Reports, could help advance efforts to create off-the-shelf CAR-T cell therapies that can be produced at scale and made more readily available to patients. https://medicalxpress.com/news/2026-08-scalable-method-generate-key-immune.html Thu, 27 Aug 2026 17:00:05 EDT news707066821 Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models. https://medicalxpress.com/news/2026-08-primate-specific-dna-reveals-link.html Thu, 27 Aug 2026 14:20:01 EDT news707055242 Two people spend an evening in the same garden and receive roughly the same number of mosquito bites. By morning, one barely notices them—while the other is covered in large, swollen, intensely itchy welts that linger for days. https://medicalxpress.com/news/2026-08-people-react-badly-mosquito-saliva.html Thu, 27 Aug 2026 11:40:01 EDT news707042522 A basketball court, soccer field or playground may help make a park inviting. But a new UC Irvine study suggests that the way public safety is approached can also influence how people use those spaces. https://medicalxpress.com/news/2026-08-safety-health.html Thu, 27 Aug 2026 09:00:01 EDT news707032501 Late-onset Alzheimer's disease (AD) is a progressive disorder characterized by cognitive decline and memory impairment, affecting an estimated 6.9 million people in the U.S. The clinical course of AD unfolds over many years, often beginning with subtle cognitive changes before progressing to overt dementia. Although the rate of decline varies among individuals, growing evidence suggests that genetic factors play a central role in shaping both the onset and trajectory of cognitive deterioration. https://medicalxpress.com/news/2026-08-accurate-alzheimer-disease-nonwhite-patients.html Thu, 27 Aug 2026 05:00:01 EDT news706881062 Overuse of reliever inhalers is associated with higher risks of developing and dying from cardiovascular disease, including heart failure, heart attack and ischemic stroke, in patients with asthma and COPD, according to a study published today in ERJ Open Research. https://medicalxpress.com/news/2026-08-overuse-inhalers-heart-asthma-copd.html Wed, 26 Aug 2026 19:10:01 EDT news706883270 Why does the same infection cause only mild symptoms in one person but more serious disease in another? A new study led by the HUN-REN BRC Szeged Momentum Systems Immunology Research Group, together with several international collaborators, suggests that part of the answer lies in how broadly the immune system can present fragments of pathogens to its own immune cells. https://medicalxpress.com/news/2026-08-immune-infections.html Wed, 26 Aug 2026 14:40:07 EDT news706973821 What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer's pathologies may be orchestrated by a molecular switch called ERBB4 when it turns on in the wrong neurons. Once activated, this misplaced signal can set off a chain reaction that disrupts brain circuits, eliminates synapses, activates glial cells, increases amyloid pathology and impairs memory. https://medicalxpress.com/news/2026-08-rogue-neuronal-root-alzheimer-disease.html Wed, 26 Aug 2026 14:20:05 EDT news706967991 Lentils, beans and chickpeas have been feeding people for thousands of years. Lentils are among the world's earliest cultivated crops, with archaeological evidence tracing them back to the beginnings of agriculture. Yet scientists are still learning what happens inside our bodies when we eat them. https://medicalxpress.com/news/2026-08-body-pulses-effects.html Wed, 26 Aug 2026 13:20:03 EDT news706957862 When the sky becomes orange and hazy from wildfire smoke, modern humans are at greater risk than our earlier ancestors would have been. https://medicalxpress.com/news/2026-08-vulnerability-wildfire-genes-evolutionary-quirk.html Wed, 26 Aug 2026 13:00:11 EDT news706957442 Dementia with Lewy bodies is one of the most common forms of dementia in older adults, after Alzheimer's disease. It takes its name from "Lewy bodies," abnormal clumps of a protein called alpha-synuclein, first identified by neurologist Friedrich Lewy, that accumulate inside neurons and contribute to damaging them. The disease manifests through visual hallucinations, fluctuating cognition, agitated and often violent movements during dreams, and motor symptoms similar to those of Parkinson's disease. https://medicalxpress.com/news/2026-08-dementia-lewy-bodies-brain-regions.html Wed, 26 Aug 2026 10:20:04 EDT news706955859 Zika virus has been spreading for decades, but it first grabbed worldwide headlines in 2016. That February, with an outbreak sweeping the Americas, the World Health Organization (WHO) declared the surge in Zika-linked birth defects a "public health emergency of international concern"—a designation that lasted until that November. An estimated 1 million people or more were infected before the wave subsided. https://medicalxpress.com/news/2026-08-experimental-zika-vaccine-reveals-cells.html Wed, 26 Aug 2026 05:00:11 EDT news706865821 In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least one in four former NFL players who died between 2016 and 2021 had chronic traumatic encephalopathy (CTE) at the time of death, a much higher prevalence compared with the general population. https://medicalxpress.com/news/2026-08-nfl-players-died-cte.html Tue, 25 Aug 2026 05:00:06 EDT news706779901 Dr. Genaro DeLeon, a resident physician at the Cleveland Clinic, couldn't decide between pursuing surgery or family medicine. https://medicalxpress.com/news/2026-08-family-medicine-shortage-future-doctors.html Mon, 24 Aug 2026 23:00:03 EDT news706797218 Allergic rhinitis and asthma are among the most common chronic diseases today, affecting hundreds of millions of people worldwide. One contributing factor is climate change, which is extending pollen seasons, increasing pollen in the air and potentially making it more allergenic. The latest guidelines from the European Academy of Allergy and Clinical Immunology (EAACI), developed with scientists from Wroclaw Medical University, show that effective allergy management goes beyond medication. Modern pollen monitoring systems, environmental forecasts and preventive measures are becoming increasingly important. https://medicalxpress.com/news/2026-08-guidelines-emphasize-pollen-allergy.html Mon, 24 Aug 2026 16:40:08 EDT news706808166 Researchers at Georgia State University have identified a previously unknown aspect of schizophrenia that offers a new way to understand how the disorder affects large-scale brain coordination. In a new study, published in the journal Translational Psychiatry, researchers introduced a method for measuring how brain networks maintain balanced activity and recover when that balance is disrupted. https://medicalxpress.com/news/2026-08-uncover-brain-network-dynamics-schizophrenia.html Mon, 24 Aug 2026 13:50:01 EDT news706797686 For decades, people exercising have been told one simple rule: Never let your knees go over your toes. During lunges, squats and many other exercises, well-meaning coaches, trainers and physical therapists repeated this advice so often that it became fitness folklore. https://medicalxpress.com/news/2026-08-knees-toes-bullet-proof-experts.html Mon, 24 Aug 2026 09:00:05 EDT news706773362 For more than three decades, scientists have sought to combat diseases caused by protein misfolding by targeting the large protein clumps that accumulate in affected tissues. Yet, despite intensive efforts, clinical success has been limited. https://medicalxpress.com/news/2026-08-tiny-protein-oligomers-earlier-diagnosis.html Sat, 22 Aug 2026 09:00:01 EDT news706538066 It's 4 a.m., you've finally drifted off, and then the phone rings. It's work calling. You have to go in. The right to disconnect from work has been protected by law in Australia since 2024. This means most employees can refuse to answer calls from work outside their regular work hours. https://medicalxpress.com/news/2026-08-oncall-disrupt.html Fri, 21 Aug 2026 18:40:03 EDT news706529007 What if we could fight cancer by specifically activating a key enzyme instead of deactivating it? That's exactly what a research team at Marburg University has achieved for the first time with the enzyme PRMT1. The scientists developed a small molecule called TR-07 that activates PRMT1. https://medicalxpress.com/news/2026-08-cancer-drug-strategy-flips-script.html Fri, 21 Aug 2026 14:20:04 EDT news706535375 Lung cancer screenings can save lives by detecting cancer in its early stages, but only 15% of eligible American adults have discussed the screening with their doctors, according to data analysis performed by University of Cincinnati Cancer Center researchers. https://medicalxpress.com/news/2026-08-lack-awareness-lung-cancer-screenings.html Fri, 21 Aug 2026 11:20:08 EDT news706528441 Mayo Clinic researchers have developed and externally validated an artificial intelligence (AI) model that can identify a potentially significant heart obstruction from routine ultrasound videos without relying on specialized Doppler imaging. The technology could help clinicians flag patients with hypertrophic cardiomyopathy (HCM) who may need additional testing, particularly in settings where specialized echocardiography expertise is limited. https://medicalxpress.com/news/2026-08-ai-clinicians-heart-obstruction-routine.html Thu, 20 Aug 2026 07:20:03 EDT news706421582 When survivors of trauma recount their experiences, they are often questioned because of how they relay their stories. They may have problems remembering what happened, or their memories may be jumbled or even contradictory. People hearing those stories—attorneys, reporters, health care workers or friends—may expect a clearer, linear narrative. https://medicalxpress.com/news/2026-08-traumatic-memories-fragmented-psychologist.html Wed, 19 Aug 2026 16:20:07 EDT news706372802 Age, genetics and lifestyle are known to influence how people respond to viral infections. Scientists also know that differences in immune responses play an important role, but exactly how these factors shape the course of an infection has remained unclear. https://medicalxpress.com/news/2026-08-early-immune-checkpoint-virus-affects.html Wed, 19 Aug 2026 10:20:08 EDT news706353181 Mention psychotherapy and many people picture a familiar movie scene: someone lying on a couch, talking about their childhood, while a therapist sits behind them taking notes. https://medicalxpress.com/news/2026-08-difference-psychotherapy-psychoanalysis.html Wed, 19 Aug 2026 09:20:03 EDT news706346101 Talking about weight can be tough. Even someone who feels ready for a doctor's help may find the conversation awkward. People living with excess weight can feel judged, stigmatized or embarrassed, "or maybe they are unaware that their condition is something that needs to be medically treated," said Dr. Deepika Laddu, an associate professor of preventive medicine at Northwestern University Feinberg School of Medicine in Chicago. https://medicalxpress.com/news/2026-08-weight-doctor.html Wed, 19 Aug 2026 08:40:05 EDT news706345442 Tens of millions of people suffer from traumatic brain injuries every year worldwide, with almost 5 million deaths. Yet when it comes to improving clinical outcomes, new research suggests the solution lies far outside hospital operating rooms. https://medicalxpress.com/news/2026-08-traumatic-brain-injury-vary-widely.html Wed, 19 Aug 2026 05:00:01 EDT news706268101 A five-week training intervention taught college students to better regulate their emotions in response to negative events, a new study finds. After the training, the students reported less emotional distress when viewing negative images or thinking about difficult events in their own lives, and brain scans revealed corresponding changes in the spontaneous functional connectivity of their brains. https://medicalxpress.com/news/2026-08-emotion-distress-brain-team.html Tue, 18 Aug 2026 05:00:01 EDT news705927251 Despite widespread COVID-19 infection in the Tsimané and Moseten populations of Bolivia, the mortality rate in these remote Indigenous groups was the lowest ever recorded for any population or region. https://medicalxpress.com/news/2026-08-tsiman-moseten-peoples-lowland-bolivia.html Mon, 17 Aug 2026 15:40:07 EDT news706199161 One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging can fully resolve. During surgery, neurosurgeons must remove as much tumor as possible while preserving critical brain functions. This makes accurate intraoperative assessment of tumor infiltration essential for more precise surgical decision-making. https://medicalxpress.com/news/2026-08-ultra-glioma-margins-3d-minutes.html Mon, 17 Aug 2026 15:00:01 EDT news706196041