https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University in Thailand has proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. https://medicalxpress.com/news/2026-05-simulation-uncovers-tuberculosis-drug-candidates.html Fri, 29 May 2026 11:20:05 EDT news699269760 Fine particles (PM₂.₅) were associated with around 79,000 preventable deaths, followed by nitrogen dioxide (NO₂), ozone (O₃) and coarser particles (PM₂.₅-₁₀, particles with a diameter between 2.5 and 10 micrometers). These are among the findings of a new study conducted by the Barcelona Institute for Global Health (ISGlobal), in collaboration with the Barcelona Supercomputing Center–Centro Nacional de Supercomputación (BSC-CNS), which provides the first Europe-wide estimate of short-term mortality associated with the combined effects of multiple pollutants across 31 European countries. The findings, published in Nature Health, support the development of impact-based early warning systems to help protect the population from the health effects of air pollution. https://medicalxpress.com/news/2026-05-combined-short-term-effects-air.html Wed, 13 May 2026 16:38:53 EDT news697909082 Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice. However, with the increase in life expectancy, the number of women in the postmenopausal stage continues to grow and, in 2021, those over 50 already represented 26% of the world's population, according to the WHO. https://medicalxpress.com/news/2026-04-age-alike-ai-unveils-molecular.html Wed, 29 Apr 2026 05:00:03 EDT news696589510 Statistics show clear differences in the population's immune system according to sex: men are more susceptible to infections and cancers, while women have stronger immune responses, which translate, for example, into better responses to vaccines. Even so, with a more reactive immune system, the probability of the body attacking itself also increases, causing 80% of autoimmune disease development to occur in women. https://medicalxpress.com/news/2026-04-women-immune-bigger-age-men.html Fri, 10 Apr 2026 11:20:04 EDT news695038681 For patients with heart failure, blood pumps can be lifesaving. But the very forces that sustain circulation can also harm it, damaging red blood cells through hemolysis and compromising the body's oxygen supply. Now, supercomputer simulations are revealing how red blood cells deform under stress, offering new insights that could lead to safer, more effective blood pump designs. https://medicalxpress.com/news/2026-04-supercomputer-simulations-reveal-early-red.html Thu, 02 Apr 2026 17:40:02 EDT news694363861 Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and respond to treatment. Researchers at the University of Illinois Urbana-Champaign are taking a new approach that combines geographic mapping techniques with gene expression analysis to visualize these spatial relationships inside tumors. https://medicalxpress.com/news/2026-03-spatial-technique-tumor-architecture.html Sat, 28 Mar 2026 10:20:01 EDT news693837103 Socioeconomic factors are widely recognized as potential modifiers of the relationship between air pollution and mortality, but the available evidence remains limited. In this context, a new study led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with the Barcelona Supercomputing Center–Centro Nacional de Supercomputación (BSC-CNS), analyzed how socioeconomic conditions and the transition to renewable energy in Europe influence vulnerability to air pollution. https://medicalxpress.com/news/2026-03-european-regions-highest-poverty-vulnerable.html Thu, 19 Mar 2026 06:00:06 EDT news693047822 Simon Fraser University scientists are embarking on a new study to discover what makes some people more resilient to brain conditions such as dementia. With dementia rates on the rise globally, the need for more informed insights into brain health has never been greater. https://medicalxpress.com/news/2026-03-secrets-healthy-brain-team.html Tue, 17 Mar 2026 17:20:03 EDT news692965294 Biological differences between women and men lead to variations in the appearance and progression of many diseases, which influence diagnosis and response to treatments. These differences also affect the relationship between diseases, as they generate different combinations, risks, and patterns of joint appearance depending on sex. However, the biological mechanisms that explain these associations have remained largely unexplored from a sex-differentiated perspective—until now. https://medicalxpress.com/news/2026-01-sex-diseases-exposes-historical-biases.html Thu, 29 Jan 2026 16:56:42 EST news688928161 More than 1 million Americans live with tremors, slowed movement and speech changes caused by Parkinson's disease—a degenerative and currently incurable condition, according to the Parkinson's Foundation and the Mayo Clinic. Beyond the emotional toll on patients and families, the disease also exerts a heavy financial burden. In California alone, researchers estimate that Parkinson's costs the state more than 6 billion dollars in health care expenses and lost productivity. https://medicalxpress.com/news/2025-12-code-parkinson-supercomputers-treatments.html Wed, 03 Dec 2025 08:41:18 EST news683973662 Harnessing the muscle of one of the world's fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever. https://medicalxpress.com/news/2025-11-supercomputer-simulation-brain.html Mon, 17 Nov 2025 08:00:02 EST news682333753 Randomized, controlled clinical trials are crucial for telling whether a new treatment is safe and effective. But often scientists don't fully report the details of their trials in a way that allows other researchers to gauge how well they designed and conducted those studies. https://medicalxpress.com/news/2025-10-ai-scientists-medical.html Thu, 23 Oct 2025 09:24:04 EDT news680430241 The human body is a complex and interconnected system, where alterations caused by one disease can promote the onset of others. This tendency for certain diseases to occur together, beyond what would be expected by chance, is called co-occurrence. Thus, although there are diseases with widely known co-occurrence in certain groups of patients, such as Crohn's disease and the development of ulcers, many of the molecular mechanisms that would explain them were, until now, unknown. https://medicalxpress.com/news/2025-09-molecular-reveals-previously-hidden-diseases.html Tue, 02 Sep 2025 11:40:04 EDT news676032001 In an advance for climate-informed disease early warning systems, a team of researchers, public health actors and meteorologists have developed a prediction model capable of forecasting dengue outbreaks in the Caribbean up to three months in advance. https://medicalxpress.com/news/2025-08-early-dengue-outbreaks-caribbean-months.html Tue, 19 Aug 2025 13:08:04 EDT news674827681 You may have heard the phrase "my heart skipped a beat" when someone was talking about a romantic encounter. In truth, hearts that beat irregularly are dangerous for your health. Atrial fibrillation (AF) is the most common type of irregular heartbeat, and over time, it can worsen and become a permanent condition, a severe disorder that's the leading preventable cause of ischemic stroke, according to the NIH. https://medicalxpress.com/news/2025-07-simulations-heart-treatments-atrial-fibrillation.html Thu, 31 Jul 2025 15:57:53 EDT news673196268 A new cancer drug candidate has demonstrated the ability to block tumor growth without triggering a common and debilitating side effect. https://medicalxpress.com/news/2025-06-cancer-drug-candidate-supercomputing-ai.html Thu, 26 Jun 2025 15:01:53 EDT news670168905 A discovery published in Nature Immunology has shed light on why the immune system is less aggressive toward self-antigens, offering new opportunities to enhance cancer immunotherapy. https://medicalxpress.com/news/2025-03-supercomputer-uncovers-immune-secret-tolerance.html Fri, 28 Mar 2025 11:01:03 EDT news662378461 Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a University of Pittsburgh team using the Bridges-2 system at the Pittsburgh Supercomputing Center, suggest how the capsid may deform to fit through the nuclear pores, revealing a potential target for future AIDS therapies. https://medicalxpress.com/news/2025-02-hiv-protein-virus-host-cell.html Tue, 18 Feb 2025 09:02:14 EST news659091729 An international team of scientists has developed a technology based on artificial intelligence (AI) for the study of minority diseases and has successfully applied it to identify the possible causes of the appearance of what is known as myasthenic-congenital syndromes, a group of rare inherited disorders that limit the ability to move and cause varying degrees of muscle weakness in patients. https://medicalxpress.com/news/2024-02-artificial-intelligence-technology-treatment-rare.html Wed, 28 Feb 2024 10:23:45 EST news628338222 Molecular simulations on the JUWELS supercomputer show how the HIV-1 virus is able to evade the human immune system. The newly discovered mechanism could prove to be the Achilles' heel of the virus and open new doors for HIV therapies. https://medicalxpress.com/news/2024-02-qa-supercomputer-simulations-hiv-therapies.html Wed, 28 Feb 2024 07:39:04 EST news628328342 Women produce physiological data that is just as predictable as men, at least when it comes to skin temperature. This might seem like common sense, but variations in body signals due to menstrual cycles, such as temperature, were used as an excuse to keep women out of clinical studies for decades. https://medicalxpress.com/news/2023-11-women-skin-temperature-men.html Thu, 09 Nov 2023 13:25:23 EST news618758716 Scientists have confirmed that human brains are naturally wired to perform advanced calculations, much like a high-powered computer, to make sense of the world through a process known as Bayesian inference. https://medicalxpress.com/news/2023-09-neural-evolution-wired-human-brains.html Thu, 14 Sep 2023 09:56:04 EDT news613904161 Let's think for a second about thought—specifically, the physics of neurons in the brain. https://medicalxpress.com/news/2022-06-supercomputer-synaptic-transmission.html Mon, 20 Jun 2022 16:27:49 EDT news574961264 To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from the Department of Energy's Oak Ridge National Laboratory developed a novel technique. https://medicalxpress.com/news/2022-01-supercomputing-exposes-potential-pathways-inhibiting.html Wed, 26 Jan 2022 09:20:01 EST news562409757 In the latest issue of Science, brain scientist Katrin Amunts and supercomputing expert Thomas Lippert explain how advances in neuroscience demand high-performance computing technology and will ultimately need exascale computing power. https://medicalxpress.com/news/2021-11-human-brain-outline-demands-supercomputing.html Fri, 26 Nov 2021 12:57:36 EST news557153851 Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve. https://medicalxpress.com/news/2021-11-antibiotic-resistance-outwitted-supercomputers.html Tue, 02 Nov 2021 12:34:31 EDT news555075267 Swift, effective action is essential to face any crisis decisively. And, if it's a global one like the COVID-19 pandemic, these actions need to be efficiently coordinated to increase their impact while lessening the initial threat. This is exactly what the PRACE COVID-19 Fast Track Call set out to achieve, by allocating thousands of years of computer simulations (free of charge) to help fight COVID-19. Now, the scientific community is reaping the lessons that stemmed from the initiative. https://medicalxpress.com/news/2021-11-viral-lessons-supercomputing.html Mon, 01 Nov 2021 15:00:04 EDT news554978599 A group of researchers at Université de Montréal has simulated the effects of more than 17,000 possible mutations of the spike protein of SARS-CoV-2, the virus responsible for COVID-19. https://medicalxpress.com/news/2021-09-evolution-covid-variants.html Fri, 17 Sep 2021 09:58:45 EDT news551091517 While the world awaits broad distribution of COVID-19 vaccines, researchers at Ohio University just published highly significant and timely results in the search for another way to stop the virus—by disrupting its RNA and its ability to reproduce. https://medicalxpress.com/news/2021-01-id-potential-anti-viral-drugs-covid-.html Thu, 21 Jan 2021 11:02:09 EST news530449324 With millions of COVID-19 cases reported across the globe, people are turning to antibody tests to find out whether they have been exposed to the coronavirus that causes the disease. But what are antibodies? Why are they important? If we have them, are we immune to COVID-19? And if not, why not? https://medicalxpress.com/news/2020-07-re-engineering-antibodies-covid-.html Thu, 30 Jul 2020 15:04:15 EDT news515340244