https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Multimodal ultrasound (MMU) is feasible for the diagnosis of neurogenic bladder (NB) in pediatric patients, according to a study published online Jan. 17 in Scientific Reports. https://medicalxpress.com/news/2026-01-multimodal-ultrasound-feasible-pediatric-neurogenic.html Wed, 28 Jan 2026 20:00:02 EST news688830773 Patients with neuropathic bladder (NB), a condition in which nerve damage affects bladder function, have a significantly higher risk of joint infections, blood clots, and other adverse events after receiving total hip replacement (THR), UT Southwestern Medical Center researchers found. https://medicalxpress.com/news/2026-01-neuropathic-bladder-patients-complications-hip.html Tue, 27 Jan 2026 12:49:29 EST news688740542 A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments. The work examines the evolution of therapeutic cancer vaccines, with a special focus on neoantigen-based vaccines—highly personalized vaccines designed using genetic mutations unique to a patient's tumor. https://medicalxpress.com/news/2026-01-cancer-vaccines-personalized-combination-treatment.html Thu, 22 Jan 2026 14:57:05 EST news688316161 Published, peer-reviewed research shows a patent-pending, virus-mimicking platform technology developed at Purdue University improves upon traditional methods of targeting bladder cancer cells with messenger RNA (mRNA) therapies. https://medicalxpress.com/news/2026-01-shelf-stable-mrna-delivery-bladder.html Sun, 18 Jan 2026 12:41:38 EST news687962359 People who are colorblind may be missing a life-saving warning sign of bladder cancer. Analysis of the electronic health records of hundreds of people found that those with color vision deficiency (CVD), or color blindness and bladder cancer had significantly worse outcomes than patients with normal vision, according to a study published in Nature Health. https://medicalxpress.com/news/2026-01-early-bladder-cancer-survival.html Sat, 17 Jan 2026 12:10:04 EST news687787356 Urology departments in England and Wales have reported seeing an increase in the number of 16- to 24-year-olds being admitted for bladder inflammation associated with ketamine use. https://medicalxpress.com/news/2026-01-ketamine-young-people-bladder-problems.html Thu, 15 Jan 2026 10:02:28 EST news687693721 Overactive bladder (OAB) is prevalent among women with fibromyalgia (FM) and is associated with higher symptom severity and comorbidity, according to a study published in Neurourology Urodynamics. https://medicalxpress.com/news/2025-12-overactive-bladder-prevalent-women-fibromyalgia.html Tue, 16 Dec 2025 09:40:02 EST news685099375 Providing surgeons feedback and education on their performance significantly improved the quality of bladder cancer operations, finds a new clinical trial led by researchers at UCL, UCLH and the University of Edinburgh. https://medicalxpress.com/news/2025-12-bladder-cancer-surgeons-feedback.html Thu, 11 Dec 2025 18:50:01 EST news684682943 Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive procedures like cystoscopies. This novel approach, detailed in a new study in The Journal of Molecular Diagnostics could reduce the need for frequent cystoscopies, lower health care costs, and improve patient comfort and outcomes. https://medicalxpress.com/news/2025-12-simple-urine-screen-bladder-cancer.html Thu, 04 Dec 2025 13:03:34 EST news684075647 Tackling a common childhood virus could open the door to preventing bladder cancer, according to new research. https://medicalxpress.com/news/2025-12-common-childhood-virus-bladder-cancer.html Wed, 03 Dec 2025 14:00:17 EST news683909101 The U.S. Food and Drug Administration has approved Pfizer's Padcev (enfortumab vedotin-ejfv), a Nectin-4 directed antibody-drug conjugate, as a perioperative neoadjuvant treatment and postcystectomy adjuvant treatment for adult patients with muscle-invasive bladder cancer (MIBC). https://medicalxpress.com/news/2025-12-fda-padcev-muscle-invasive-bladder.html Wed, 03 Dec 2025 07:23:36 EST news683968952 Bacteria may be the next frontier in cancer treatment, according to a team led by researchers at Penn State that devised a new approach of creating bacteria-derived mixtures—or cocktails—to help fight bladder cancer. They tested their mixtures of good and bad bacteria on patient tumor samples and in mice, finding that the cocktails significantly boost the immune system's ability to fight cancer. https://medicalxpress.com/news/2025-12-cancer-bacterial-product-cocktails-personalized.html Tue, 02 Dec 2025 10:45:41 EST news683894701 People with type 1 diabetes (previously called juvenile diabetes) are 4.29 times more likely to develop bladder cancer, according to a systematic review and meta-analysis by researchers at the Keck School of Medicine of USC. The new analysis is the first to control for the effects of tobacco smoking, a factor that likely obscured the heightened risk in earlier studies. https://medicalxpress.com/news/2025-11-diabetes-significantly-bladder-cancer.html Thu, 20 Nov 2025 04:49:04 EST news682836541 Imagine a targeted approach to bladder cancer that spares healthy cells while delivering chemotherapy directly to cancerous ones, offering hope for patients with advanced stages of the disease. https://medicalxpress.com/news/2025-11-drug-bladder-cancer-patients.html Mon, 17 Nov 2025 11:28:04 EST news682601281 Shilpa Gajarawala struggled with hot flashes, night sweats, sleep problems and brain fog. But given her history of breast cancer, treating these menopausal symptoms with hormone therapy wasn't an option. https://medicalxpress.com/news/2025-11-hormone-therapy-menopause-options.html Sun, 16 Nov 2025 06:05:18 EST news682495506 According to researcher Anne Robertson, the bladder is not considered a particularly glamorous organ, despite hosting many of the same physiological elements and processes as the heart. https://medicalxpress.com/news/2025-11-unfolding-truth-bladder-function-insights.html Mon, 10 Nov 2025 16:40:04 EST news682015202 FX-909, a first-in-class investigational oral small molecule inhibitor of peroxisome proliferator-activated receptor gamma (PPARG), showed early signs of clinical benefit in patients with advanced urothelial carcinoma, according to results from a phase I clinical trial presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 22–26 in Boston. https://medicalxpress.com/news/2025-10-therapy-patients-advanced-bladder-cancer.html Wed, 22 Oct 2025 13:30:01 EDT news680358245 Patients with muscle-invasive bladder cancer who test positive for circulating tumor (ct)DNA after surgery to remove the cancer benefit from immunotherapy with atezolizumab compared to placebo whereas ctDNA-negative patients may potentially be spared unnecessary treatment. The finding is based on results from the global, randomized, phase 3 IMvigor011 trial co-led by investigators from Dana-Farber Cancer Institute, the Technical University of Munich, and Queen Mary University of London, UK. https://medicalxpress.com/news/2025-10-blood-surgical-immunotherapy-muscle-invasive.html Mon, 20 Oct 2025 12:51:03 EDT news680183461 The risk for overactive bladder (OAB) is associated with both short and long sleep duration, according to a study published online Sept. 17 in Frontiers in Medicine. https://medicalxpress.com/news/2025-10-overactive-bladder.html Wed, 15 Oct 2025 13:00:01 EDT news679750542 Researchers have developed a way to predict how lung cancer cells will respond to different therapies, allowing people with the most common form of lung cancer to receive more effective individualized treatment. https://medicalxpress.com/news/2025-10-google-approach-cell-tumor-personalized.html Mon, 13 Oct 2025 11:48:03 EDT news679574881 Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor. However, the biological mechanisms behind these risk factors remain unclear. Since cancer can take decades to develop, it is important to look at healthy tissues to understand the very first steps of the disease, with the goal of improving risk prediction, prevention, and early diagnosis. https://medicalxpress.com/news/2025-10-biological-sex-healthy-bladder-tissue.html Wed, 08 Oct 2025 11:00:01 EDT news679073461 Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive bladder cancer, according to results of a new Phase III randomized trial. https://medicalxpress.com/news/2025-09-therapy-surgery-safely-pelvic-relapse.html Mon, 29 Sep 2025 14:00:05 EDT news678358681 A new international study has uncovered a concerning lack of public understanding about cystitis and urinary tract infections (UTIs)—common health issues that disproportionately affect women. The findings, which also highlight widespread misconceptions about prevention and treatment, underscore the urgent need for education to combat rising antibiotic resistance. https://medicalxpress.com/news/2025-09-highlights-utis-antibiotic-resistance.html Mon, 22 Sep 2025 10:19:57 EDT news677755193 Magnesium depletion is associated with an increased risk for overactive bladder (OAB), according to a study published online Sept. 1 in Scientific Reports. https://medicalxpress.com/news/2025-09-magnesium-depletion-linked-overactive-bladder.html Thu, 18 Sep 2025 13:30:01 EDT news677420032 Researchers from the University of Birmingham's Bladder Cancer Research Center have used a new method to detect chemical changes in the DNA in an individual's urine sample; epigenetic changes, called methylation. https://medicalxpress.com/news/2025-09-tumor-dna-urine-bladder-cancer.html Wed, 17 Sep 2025 15:20:04 EDT news677341202 A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle-aged adults, suggests research published in the open access journal BMJ Public Health. https://medicalxpress.com/news/2025-09-bout-cystitis-presence-urogenital-cancers.html Tue, 16 Sep 2025 18:30:05 EDT news677146114 The U.S. Food and Drug Administration has approved Inlexzo (gemcitabine intravesical system) for the treatment of patients with certain types of bladder cancer. https://medicalxpress.com/news/2025-09-fda-inlexzo-bladder-cancer.html Thu, 11 Sep 2025 16:12:03 EDT news676825921 Urothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the United States. Despite recent advances, the 5-year survival rate for metastatic UC remains about 5% to 10%. https://medicalxpress.com/news/2025-09-repurposing-diabetes-medication-prime-car.html Wed, 10 Sep 2025 13:00:01 EDT news676727343 Bladder cancer is a painful and often recurring disease, not just for humans, but for our canine companions as well. Urothelial carcinoma, the most common type of bladder cancer, affects both species in remarkably similar ways—from the genetics to the clinical progression. This shared burden also means a shared challenge: how to detect and treat the aggressive form of the disease that's responsible for most relapses. https://medicalxpress.com/news/2025-09-discovery-biomarker-early-bladder-cancer.html Fri, 05 Sep 2025 10:40:01 EDT news676286585 Modest amounts of medical debt in collections persist for years after cancer diagnosis, according to a study published online Aug. 28 in JAMA Oncology. https://medicalxpress.com/news/2025-09-medical-debt-persists-cancer-diagnosis.html Tue, 02 Sep 2025 13:40:02 EDT news676039049