https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. An international collaboration of researchers have successfully adapted a Japanese oral health screening tool for use among English-speaking older adults in the United States, potentially enabling earlier detection of oral frailty—an age-related decline in oral and pharyngeal function associated with physical frailty, malnutrition, and increased mortality risk. https://medicalxpress.com/news/2026-01-screening-tool-older-adults-oral.html Mon, 26 Jan 2026 12:04:35 EST news688651442 Frailty is a syndrome resulting from age-related decline across multiple organ systems. A new study, conducted at the University of Jyväskylä, Finland, shows that slower reaction time and lower response accuracy in cognitive tasks are associated with higher levels of frailty. Notably, this association can already be detected in late midlife, among individuals aged 57 to 70 years. https://medicalxpress.com/news/2025-12-cognitive-late-midlife-frailty-older.html Thu, 18 Dec 2025 00:00:01 EST news685198671 Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these two factors alone contributing around 17% of the overall risk, suggest the findings of a large international study, published in the open access journal General Psychiatry. https://medicalxpress.com/news/2025-12-concurrent-frailty-depression-boost-dementia.html Tue, 16 Dec 2025 18:30:01 EST news685099434 A new international study published in Osteoporosis International and led by Monash's Center for Medicine Use and Safety (CMUS) has investigated the risks of a second hip fracture, subsequent fractures, and death in people prescribed two different classes of bone strengthening medications. https://medicalxpress.com/news/2025-12-men-women-medications-broken-bones.html Mon, 08 Dec 2025 08:50:38 EST news684405962 A new study shows that older adults with type 2 diabetes who start treatment with sodium–glucose cotransporter-2 (SGLT-2) inhibitors—such as empagliflozin (Jardiance) and dapagliflozin (Farxiga)—or glucagon-like peptide-1 (GLP-1) receptor agonists—such as semaglutide (Ozempic) and liraglutide (Victoza)—experience slower progression of frailty over one year compared with those starting other diabetes medications. https://medicalxpress.com/news/2025-12-diabetes-drugs-older-adults-frailty.html Wed, 03 Dec 2025 13:02:46 EST news683989262 Researchers have uncovered a major blind spot in the way doctors assess future health risk in young adults who suffer a heart attack. https://medicalxpress.com/news/2025-11-frailty-young-heart-patients-linked.html Thu, 27 Nov 2025 04:13:14 EST news683439146 "Social frailty" is a major dementia risk. A UNSW researcher is changing how to spot and treat it early. https://medicalxpress.com/news/2025-11-staying-social-aging-brains.html Thu, 20 Nov 2025 08:11:05 EST news682848661 A study published in Nutrients has found that a higher intake of ultra-processed foods (UPF) was not associated with the development of frailty among middle-aged and older adults. However, UPF consumption was associated with small but significant declines in physical function, including slower gait speed in both men and women, as well as weaker grip strength in men. https://medicalxpress.com/news/2025-10-ultra-food-consumption-linked-declines.html Thu, 30 Oct 2025 17:00:05 EDT news681061827 Frailty threatens older individuals because it increases their vulnerability to detrimental health outcomes, such as falling, longer hospitalization, or even shortened life expectancy. New research exploring the linkage between frailty and mortality risk points to retaining gonad function as a potent strategy to fight late-life frailty. https://medicalxpress.com/news/2025-10-oldest-dogs-reveal-potential-key.html Tue, 28 Oct 2025 11:10:04 EDT news680868345 Socializing could help to reverse frailty in older people, according to new research published in the American Journal of Epidemiology. https://medicalxpress.com/news/2025-10-socializing-reverse-frailty-older-people.html Thu, 23 Oct 2025 10:30:59 EDT news680434249 Researchers at Zhengzhou University report evidence that physical frailty is associated with dementia and that genetic background, brain structure, and immunometabolic function may mediate this link. https://medicalxpress.com/news/2025-09-uk-biobank-analysis-higher-dementia.html Tue, 23 Sep 2025 08:00:01 EDT news677753450 A new study suggests that physical frailty may contribute to the development of dementia. The study was published in Neurology. https://medicalxpress.com/news/2025-09-physical-frailty-contribute-dementia.html Wed, 17 Sep 2025 16:00:01 EDT news677317561 Gastrointestinal (GI) complications, such as postoperative ileus (POI) and intra-abdominal infections (IAI), remain a major concern after radical cystectomy for bladder cancer. Even with advances in surgical techniques, including robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC), and the adoption of enhanced recovery protocols, these complications continue to affect a substantial proportion of patients. They not only prolong hospital stays but also increase patient morbidity, underscoring the need to identify risk factors beyond surgical technique alone. https://medicalxpress.com/news/2025-09-frailty-fuels-gut-imbalance-surgery.html Mon, 08 Sep 2025 14:23:04 EDT news676560182 Younger adults who experience frailty face a higher risk of death and emergency hospital admission, according to new University of Dundee research published in The Lancet Healthy Longevity. The study, led by Dr. Daniel Morales from the University's School of Medicine, explored whether the electronic frailty index (eFI), which is already used for older adults, could also identify vulnerable younger people who might benefit from early support. https://medicalxpress.com/news/2025-08-younger-adults-frailty-higher-death.html Tue, 26 Aug 2025 12:41:04 EDT news675430861 It's a fact of life: Some people age better than others. Some ease into their 90s with mind and body intact, while others battle diabetes, Alzheimer's or mobility issues decades earlier. Some can withstand a bad fall or bout of the flu with ease, while others never leave the hospital again. https://medicalxpress.com/news/2025-08-people-age-faster-genes-play.html Wed, 20 Aug 2025 15:08:04 EDT news674921281 Researchers have found that a common tool used by clinicians for predicting kidney failure could be underestimating the risk of failure for some people. The study, "Frailty in Adults with Chronic Kidney Disease and Validation of the Kidney Failure Risk Equation in Frailty Sub-Groups," is published in the Clinical Journal of the American Society of Nephrology. https://medicalxpress.com/news/2025-08-current-diagnostic-tool-underestimates-kidney.html Fri, 08 Aug 2025 12:13:03 EDT news673873981 A new study has identified genetic variants linked to brain function, immune defense and metabolism that contribute to the development of frailty in older people. The study, published in Nature Aging by researchers from Karolinska Institutet, provides new biological insights into the onset of frailty. https://medicalxpress.com/news/2025-08-genes-reveal-older-people-frailty.html Tue, 05 Aug 2025 05:00:07 EDT news673518384 A new study led by researchers at King's College London, in collaboration with the University of Nottingham, suggests that chronic inflammation may link frailty, social disadvantage and increased cardiovascular disease (CVD) risk. https://medicalxpress.com/news/2025-08-inflammation-linked-frailty-social-deprivation.html Mon, 04 Aug 2025 12:18:05 EDT news673528682 A new study led by researchers at National Taiwan University (NTU) reveals that subtle differences in retinal thickness between the eyes—known as inter-eye retinal asymmetry—may serve as an early and accessible biomarker for cognitive frailty, a high-risk condition combining mild cognitive impairment with physical frailty. https://medicalxpress.com/news/2025-06-retinal-asymmetry-eyes-early-indicator.html Fri, 20 Jun 2025 09:52:04 EDT news669631921 Frailty is a condition characterized by increased vulnerability and decline in physical function. It's a growing concern in the aging population, particularly among those with heart disease. https://medicalxpress.com/news/2025-06-s100a1-potential-biomarker-frailty-older.html Tue, 10 Jun 2025 12:47:04 EDT news668778421 New research from the Royal College of Anesthetists (RCoA) and the University of Nottingham reveals that nearly three-quarters (71%) of U.K. hospitals are not routinely screening older surgical patients aged 60 and older for frailty—despite clear evidence that frailty significantly increases the risk of complications, including longer hospital stays, delirium, and even death. https://medicalxpress.com/news/2025-05-majority-uk-hospitals-screen-older.html Tue, 27 May 2025 12:03:04 EDT news667566182 Loneliness, feeling older than your age and a negative attitude to aging are all associated with early stages of frailty, even in people as young as 40, new research reveals. The research is published in the journal BMC Public Health. https://medicalxpress.com/news/2025-05-frailty-early-age.html Thu, 15 May 2025 08:34:04 EDT news666516842 Looking at your biological age—how old your body really is—can give a clearer picture of your heart disease risk than traditional tools alone. This finding comes from a newly published multicenter study conducted in collaboration between the Universities of Jyväskylä, Tampere, and Helsinki, the Finnish Institute for Health and Welfare (THL), Finland, and the Karolinska Institutet, Sweden. https://medicalxpress.com/news/2025-05-biological-age-cardiovascular-disease-morbidity.html Thu, 08 May 2025 16:21:03 EDT news665940061 A new study published in the European Journal of Nutrition has suggested that habitual coffee consumption of 4–6 cups and over (with one cup measuring at 125ml) per day is associated with a reduced risk of frailty. The study is the first to analyze the relationship between coffee consumption and the underlying components of frailty. https://medicalxpress.com/news/2025-04-coffee-frailty.html Tue, 29 Apr 2025 09:59:49 EDT news665139554 A new study links changes in frailty, a measure of decreased physiological capacity that leads to fatigue, slow walking, muscle weakness, physical inactivity, and weight loss, to five-year survival rates in older women with breast cancer. These findings suggest that managing frailty during chemotherapy could improve outcomes. https://medicalxpress.com/news/2025-04-links-frailty-year-mortality-older.html Mon, 07 Apr 2025 15:53:03 EDT news663259981 Researchers have successfully improved the Electronic Frailty Index (eFI)—a tool that uses data to predict older patients' risks of living with frailty—so medical professionals can provide holistic care, help to prevent falls, reduce burdensome medications and provide targeted exercise programs to maximize independence. https://medicalxpress.com/news/2025-03-algorithm-older-people-frailty-doctors.html Mon, 31 Mar 2025 19:10:01 EDT news662638381 Investigators at Mass General Brigham have developed a tool that can identify older adults at increased risk of emergency health care needs, rehospitalization or death. The tool measured patient frailty, an aging-related syndrome, by integrating the health records of more than 500,000 individuals collected across multiple hospitals at Mass General Brigham. https://medicalxpress.com/news/2025-02-frailty-tool-vulnerable-older-adults.html Fri, 21 Feb 2025 11:00:05 EST news659347371 Results from the Systolic Blood Pressure Intervention Trial (SPRINT) have supported lower blood pressure targets among community-dwelling older adults with hypertension to reduce the risk of cardiovascular disease and early death, but intensive blood pressure lowering can also increase risks of developing acute kidney injury and experiencing dangerously low blood pressure. https://medicalxpress.com/news/2025-02-pros-cons-aggressive-blood-pressure.html Wed, 19 Feb 2025 06:16:03 EST news659168161 Aging is a normal part of the life course. It doesn't matter how many green smoothies you drink, or how many "anti-aging" skin care products you use, you can't stop the aging process. https://medicalxpress.com/news/2025-02-difference-aging-frailty-inevitable.html Wed, 12 Feb 2025 13:50:04 EST news658588124 India is home to more than 150 million people over the age of 60. This figure will more than double by 2050, reaching roughly the current total population of the United States, according to projections from the United Nations Population Fund. https://medicalxpress.com/news/2024-12-good-shield-frailty-older-adults.html Tue, 10 Dec 2024 11:16:03 EST news653051755