https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. New research indicates that a drug commonly prescribed for gout may also lower the risk of heart attack and stroke when taken at an appropriate dose. https://medicalxpress.com/news/2026-02-gout-early.html Mon, 09 Feb 2026 22:10:01 EST news689848812 Gout, a type of inflammatory arthritis caused by a buildup of uric acid (urate) in the body, affects 5.1% of U.S. adults (over 12 million), including 10% of those aged 65 or older. Urate is produced by the body when breaking down compounds called purines and normally dissolves in the blood, but when levels are high, they can precipitate out as monosodium urate crystals which can deposit in the joints. https://medicalxpress.com/news/2026-02-glucose-lowering-sglt2i-drugs-patients.html Tue, 03 Feb 2026 07:30:07 EST news689325843 A new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout. https://medicalxpress.com/news/2026-01-gout-medication-heart.html Mon, 26 Jan 2026 11:00:01 EST news688379701 A new paper in Rheumatology Advances in Practice indicates that TikTok videos about gout are commonly misleading, inconsistent, or inaccurate. The paper is titled "Gout, TikTok and misleading information: A content analysis." https://medicalxpress.com/news/2025-12-tiktok-gout-advice-health-professionals.html Wed, 10 Dec 2025 00:10:02 EST news684492708 Gout is the most common form of inflammatory arthritis, with a worldwide prevalence of approximately 4%. The accumulation of monosodium urate crystals in gout leads to the clinical manifestations of the disease and, if left inadequately treated, leads to chronic arthritis with joint damage. Due to its anti-inflammatory properties, colchicine, an alkaloid drug derived from the autumn crocus plant, is commonly used in the management of gout for both prophylaxis and treatment of gout flares. https://medicalxpress.com/news/2025-12-people-colchicine-joint.html Tue, 02 Dec 2025 12:03:29 EST news683899382 Gout flares are associated with cardiovascular events. Treating gout to target serum urate levels prevents flares, but whether such treatment can also prevent cardiovascular events is unknown. https://medicalxpress.com/news/2025-06-ideas-gout.html Mon, 16 Jun 2025 11:10:01 EDT news669287945 Every now and then an athlete comes along who makes people wonder, "how are they so fast?" https://medicalxpress.com/news/2025-03-length-devastating-finish-spikes-science.html Mon, 31 Mar 2025 14:40:01 EDT news662647393 Gout flares are commonly underreported among U.S. adults with gout, according to a study published in the January issue of ACR Open Rheumatology. https://medicalxpress.com/news/2025-01-gout-flares-underreported-adults.html Tue, 14 Jan 2025 14:20:01 EST news656086547 At just 16 years of age, Gout Gout captured the world's attention with his record-breaking performance at the Australian National All-Schools Championships. https://medicalxpress.com/news/2024-12-pressure-diamonds-australian-sprint-sensation.html Wed, 11 Dec 2024 10:58:33 EST news653137108 Use of sodium glucose cotransporter 2 (SGLT-2) inhibitor drugs to treat type 2 diabetes may also help to lower the risk of recurrent kidney stones and gout flare-ups, finds a study from Canada published by BMJ. https://medicalxpress.com/news/2024-11-diabetes-drugs-linked-kidney-stones.html Fri, 01 Nov 2024 14:36:42 EDT news649690594 A major international study has found that gout is a chronic illness in which genetics is a major cause, rather than the lifestyle choices of the sufferer. https://medicalxpress.com/news/2024-10-genetics-lifestyle-major-gout.html Tue, 15 Oct 2024 10:29:03 EDT news648206941 Scientists at St. Jude Children's Research Hospital have used cryo-electron microscopy to generate ten structures of URAT1, a protein linked to gout. Gout is a type of arthritis caused by excess urate levels, a byproduct of purine metabolism. URAT1 is a transporter that regulates urate levels, controlling its reabsorption in the kidneys. https://medicalxpress.com/news/2024-09-urate-reveal-mechanism-important-drug.html Mon, 09 Sep 2024 16:42:03 EDT news645118921 Higher consumption of alcoholic beverages is associated with a higher risk for gout among both sexes, according to a study published online Aug. 28 in JAMA Network Open. https://medicalxpress.com/news/2024-08-greater-alcohol-intake-higher-gout.html Thu, 29 Aug 2024 13:10:00 EDT news644155798 Patients with gout, especially those younger than 60 years, have an increased risk for benign prostatic hyperplasia (BPH), according to a study published online Dec. 26 in Diagnostics. https://medicalxpress.com/news/2024-02-benign-prostatic-hyperplasia-patients-gout.html Thu, 01 Feb 2024 10:10:01 EST news626003446 Inflammatory bowel disease (IBD) is strongly associated with gout, according to a study published online Sept. 1 in JGH Open. https://medicalxpress.com/news/2023-10-inflammatory-bowel-disease-higher-gout.html Tue, 03 Oct 2023 15:50:03 EDT news615567002 An anti-inflammatory drug commonly used to treat gout could significantly improve outcomes in patients with mild-to-moderate COVID-19 infections, according to research by a team led by University of Georgia professor Ralph Tripp. https://medicalxpress.com/news/2023-07-commonly-gout-drug-effective-covid-.html Thu, 27 Jul 2023 12:24:53 EDT news609679488 For patients with gout and type 2 diabetes, sodium-glucose cotransporter-2 inhibitors (SGLT2is) are associated with a reduced risk for recurrent gout flares and gout-primary emergency department visits and hospitalizations, and they confer cardiovascular benefits, according to a study published online July 25 in the Annals of Internal Medicine. https://medicalxpress.com/news/2023-07-sglt2i-linked-flare-adults-gout.html Tue, 25 Jul 2023 15:10:01 EDT news609516323 The University of Oxford, U.K., has led a study into the relationship between gout and neurodegenerative disease. In the paper, "Association of gout with brain reserve and vulnerability to neurodegenerative disease," published in Nature Communications, the team finds remarkable links between the common arthritis joint ailment and neurodegenerative disease. https://medicalxpress.com/news/2023-06-gout-strongly-gray-neurodegenerative-disease.html Mon, 12 Jun 2023 09:12:37 EDT news605779952 Due to a policy decision in 2010 by the U.S. Food and Drug Administration (FDA), the price of a prescription for the therapeutic gout drug colchicine increased nearly 16-fold from $11.25 in 2009 to $190.49 in 2011. Out-of-pocket costs for patients who took the drug jumped more than four-fold from $7.37 to $39.49 over the same period. https://medicalxpress.com/news/2023-05-sharp-price-gout-drug-colchicine.html Mon, 08 May 2023 11:00:01 EDT news602752904 A history of gout is associated with an increased risk for benign paroxysmal positional vertigo (BPPV) and Meniere disease, according to a study published online Dec. 26 in the Journal of Clinical Medicine. https://medicalxpress.com/news/2023-02-history-gout-bppv-meniere-disease.html Fri, 24 Feb 2023 13:10:01 EST news596466382 Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson. https://medicalxpress.com/news/2022-12-ancient-disease-treatment-gout.html Tue, 13 Dec 2022 16:46:18 EST news590172371 In a study published in Arthritis & Rheumatology that included nearly 1.3 million men aged 20–39 years who participated in three serial health check-ups at two-year intervals, men with metabolic syndrome (MetS) and those who developed MetS—especially those with the MetS components of elevated triglycerides and abdominal obesity—had higher risks of developing gout. https://medicalxpress.com/news/2022-11-metabolic-syndrome-factor-gout.html Wed, 23 Nov 2022 04:27:07 EST news588400022 Gout is more prevalent in adults self-reporting Black versus White race, but these differences are attenuated after full adjustment for all risk factors, according to a study published online Aug. 15 in JAMA Network Open. https://medicalxpress.com/news/2022-08-gout-prevalent-black-white-adults.html Tue, 16 Aug 2022 13:19:02 EDT news579874741 When gout flares up, the joint pain is often excruciating. But that's not the only worry tied to this common inflammatory arthritic condition. https://medicalxpress.com/news/2022-08-gout-flare-ups-heart-disease-weeks.html Wed, 03 Aug 2022 15:24:31 EDT news578759063 Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients. A recent clinical trial published in Arthritis & Rheumatology has found that low doses of a less commonly used drug called benzbromarone may be a better option, however. https://medicalxpress.com/news/2022-07-clinicians-reconsider-standard-therapy-gout.html Thu, 07 Jul 2022 03:44:26 EDT news576384256 An analysis of nearly two decades of data has revealed that Native Hawaiian study participants had more than twice the risk of developing gout as older adults, relative to white participants. Black and Japanese participants had the second and third highest risk, respectively. https://medicalxpress.com/news/2022-05-native-hawaiians-gout-reveals.html Mon, 30 May 2022 15:48:23 EDT news573144500 Just one in three patients with gout in the U.K. received preventative medication within a year of diagnosis, new research has found. The study is published today in The Lancet Regional Health—Europe by researchers from King's. https://medicalxpress.com/news/2022-05-people-gout-medication.html Thu, 26 May 2022 10:44:40 EDT news572780676 Gout is the most common cause of inflammatory arthritis and affects an estimated 20,000 people in Edinburgh alone. https://medicalxpress.com/news/2022-04-gout-app-patients-effects-disorder.html Tue, 19 Apr 2022 15:18:02 EDT news569600280 (HealthDay)—For patients with gout and chronic kidney disease (CKD), no associations with increased mortality were seen for allopurinol initiation, achieving target serum urate (SU) levels, or allopurinol dose escalation, according to a study published online Jan. 25 in the Annals of Internal Medicine. https://medicalxpress.com/news/2022-01-allopurinol-tied-higher-mortality-patients.html Tue, 25 Jan 2022 13:10:01 EST news562337451 New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that allopurinol and febuxostat may effectively lower urate levels when used in a treat-to-target approach. Importantly, both urate-lowering therapies were very effective with 90% of patients reaching target urate levels. Additionally, both appeared safe, with no evidence of increased cardiovascular toxicity. https://medicalxpress.com/news/2021-11-treat-to-target-urate-lowering-strategy-gout-effectively.html Tue, 02 Nov 2021 17:00:38 EDT news555091235