https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida albicans can grow in an uncontrolled manner on the oral mucosa, causing oral thrush. https://medicalxpress.com/news/2025-12-immune-mucosal-fungi.html Mon, 15 Dec 2025 15:15:43 EST news685034101 Diagnosing osteoarthritis often occurs in the late stages when cartilage degradation is severe, making it difficult to distinguish it from other types of arthritis and to determine the best treatment plan. https://medicalxpress.com/news/2024-12-early-osteoarthritis-diagnosis.html Wed, 18 Dec 2024 03:10:06 EST news653646061 The U.S. Food and Drug Administration has approved UCB's Bimzelx (bimekizumab-bkzx) for the treatment of adults with moderate-to-severe hidradenitis suppurativa. https://medicalxpress.com/news/2024-11-fda-bimzelx-hidradenitis-suppurativa.html Tue, 26 Nov 2024 07:10:01 EST news651826745 Automated quantitative tests for NT-proBNP and interleukin 1 receptor-like 1 (IL-1 RL1) can identify high-risk congenital heart disease (CHD) in newborns, according to a study published in JAMA Network Open. https://medicalxpress.com/news/2024-06-nt-probnp-il-rl1-high.html Mon, 24 Jun 2024 14:58:02 EDT news638459881 Cedars-Sinai Guerin Children's investigators have advanced our understanding of the role that blood platelets play in Kawasaki disease, a serious illness that primarily affects children younger than 5 years old and causes their blood vessels to swell. https://medicalxpress.com/news/2023-07-reveals-blood-platelets-play-important.html Mon, 24 Jul 2023 14:35:03 EDT news609428101 Injections of an engineered antibody known as AMY109, given every month, were found to reduce lesion volume and lessen scar tissue and organ adhesions in monkeys with endometriosis. https://medicalxpress.com/news/2023-02-long-acting-recycling-antibody-endometriosis.html Thu, 23 Feb 2023 16:35:39 EST news596392534 Interleukin (IL)-15 is a cytokine with different modes of action, and a new article describes why it is important to selectively target the mode of action of the cytokine rather than IL-15 itself to inhibit its activity. The article is published in the Journal of Interferon & Cytokine Research (JICR). https://medicalxpress.com/news/2023-01-importance-mode-action-il-.html Mon, 23 Jan 2023 12:57:45 EST news593701063 Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite. https://medicalxpress.com/news/2022-12-immune-evolved-alarm-molecule-inflammation.html Fri, 16 Dec 2022 14:00:05 EST news590403995 A medication used to treat asthma and eczema can improve survival rates for patients with moderate to severe COVID-19, a clinical trial conducted at UVA Health suggests. https://medicalxpress.com/news/2022-08-medicine-asthma-eczema-covid-patients.html Thu, 11 Aug 2022 16:48:02 EDT news579455277 The risk of infection during pregnancy has always been a concern, but the high rate of illness during the COVID-19 pandemic has highlighted the potential impact of infection on a developing brain. https://medicalxpress.com/news/2022-07-explores-infection-effect-fetal-brain.html Thu, 21 Jul 2022 15:40:03 EDT news577636801 The messenger substance interleukin-3 produced by the body was previously considered to be pro-inflammatory in bronchial asthma. A research team from Universitätsklinikum Erlangen has now shown for the first time that the administration of interleukin-3, or IL-3 for short, can have a positive effect on chronic inflammatory respiratory disease. https://medicalxpress.com/news/2022-04-messenger-substance-inflammatory-alleviate-asthma.html Thu, 21 Apr 2022 08:49:29 EDT news569749767 A novel drug almost entirely cleared moderate to severe psoriasis in over 60% of the patients who took part in two phase three clinical trials of a new drug. https://medicalxpress.com/news/2021-04-drug-gamechanger-psoriasis-treatment.html Mon, 26 Apr 2021 09:52:52 EDT news538649569 The small intestine is ground zero for survival of animals. It is responsible for absorbing the nutrients crucial to life and it wards off toxic chemicals and life-threatening bacteria. https://medicalxpress.com/news/2021-03-duty-gut-immune-food.html Thu, 18 Mar 2021 14:00:07 EDT news535272973 (HealthDay)—Pediatric patients with COVID-19 rarely have systemic inflammation, according to a study published online June 3 in JAMA Network Open. https://medicalxpress.com/news/2020-06-inflammation-rare-pediatric-covid-patients.html Thu, 04 Jun 2020 12:49:56 EDT news510493793 (HealthDay)—Insulin infusion helps achieve glycemic targets and may reduce the risk for poor outcomes in patients with hyperglycemia and COVID-19, according to a study published online May 19 in Diabetes Care. https://medicalxpress.com/news/2020-05-glycemic-aid-covid-outcomes.html Fri, 29 May 2020 11:30:02 EDT news509969561 A potential new treatment for type 2 diabetes has multiple, positive effects on health and metabolism in mice, reports a study in Nature. The new drug might have potential for treating a variety of disorders in addition to type 2 diabetes, such as muscle atrophy, although clinical trials in humans are needed. https://medicalxpress.com/news/2019-09-diabetes-drug-added-benefits.html Thu, 26 Sep 2019 09:33:09 EDT news488709184 The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team led by researchers from the Technical University of Munich (TUM) has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell. https://medicalxpress.com/news/2019-09-quality-immune-chaperones-immature-molecules.html Wed, 25 Sep 2019 08:14:32 EDT news488618067 Your immune system comes ready for battle against bacteria, viruses, fungi and even cancer. But in cases of autoimmune disease, the immune system's superpowers turn it into a supervillain. Now, Salk Institute scientists have discovered a way to stop certain immune system cells from mistakenly attacking the body. Their findings, published the week of August 26, 2019, in the journal Proceedings of the National Academy of Sciences, suggest a new way to target Th17 helper T cells, a type of immune cell that produces interleukin 17, a molecule known to be at the root of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis and psoriasis. Previous efforts targeting Th17 helper T cells have had limited success. https://medicalxpress.com/news/2019-08-scientists-block-inflammatory-molecules-mouse.html Wed, 28 Aug 2019 10:16:36 EDT news486206179 A study of high school and college football players suggests that biomarkers in the blood may have potential use in identifying which players are more likely to need a longer recovery time after concussion, according to a study published in the July 3, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology. https://medicalxpress.com/news/2019-07-concussion-biomarkers-blood-recovery.html Wed, 03 Jul 2019 16:00:01 EDT news481351868 A study, published today in PNAS, has found a potential treatment for patients with complex regional pain syndrome (CRPS). https://medicalxpress.com/news/2019-06-treatment-option-complex-regional-pain.html Tue, 11 Jun 2019 08:00:01 EDT news479458634 Researchers at the University of Gothenburg, Sweden, have clarified the link between the molecule interleukin-6 (IL-6) in the brain and obesity. In experiments on rats and mice, they show that the molecule does affect the risk of obesity, and also where this effect occurs in the brain. https://medicalxpress.com/news/2019-05-brain-mechanisms-body-weight.html Fri, 03 May 2019 07:30:04 EDT news476087145 Minor infections can become fatal: Millions of people die each year from sepsis, an overreaction of the immune system. A new immune signaling molecule designed by a research team from the Technical University of Munich (TUM) now provides the basis for potential new approaches in sepsis therapy. https://medicalxpress.com/news/2019-01-evolution-molecules-door-sepsis-therapy.html Thu, 24 Jan 2019 07:54:48 EST news467538878 Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism. https://medicalxpress.com/news/2018-12-belly-fat-humans.html Thu, 27 Dec 2018 11:00:04 EST news465110062 A team of Russian scientists has identified the role of the interleukin-6 molecule in the development of allergic asthma. It may comprise a new target for the treatment of this disease. The results are published in Frontiers in Immunology. https://medicalxpress.com/news/2018-12-scientists-molecular-allergic-asthma-treatment.html Tue, 18 Dec 2018 10:10:01 EST news464348214 Itch is easily one of the most annoying sensations. For chronic skin diseases like eczema, it's a major symptom. Although it gives temporary relief, scratching only makes things worse because it can cause skin damage, additional inflammation and even more itch. EMBL researchers have now found a way to stop itch with light in mice. Nature Biomedical Engineering publishes their results on 17 December 2018. https://medicalxpress.com/news/2018-12-using-light-to-stop-itch.html Mon, 17 Dec 2018 11:00:05 EST news464253522 Researchers at University Putra Malaysia found a relationship between some markers of inflammation in the body and the aggressiveness of certain malignant tumours. https://medicalxpress.com/news/2018-11-ways-tumour-aggression.html Mon, 26 Nov 2018 07:29:35 EST news462439771 Inflammatory bowel disease (IBD), which afflicts millions of people worldwide, arises when the immune system mounts an overly aggressive response against microorganisms, dietary substances, or cells of the gut. A*STAR researchers have identified specific cells and molecular signals that maintain appropriate immune activity, and that may be disrupted when IBD develops. The insights open possibilities for new treatments to combat IBD. https://medicalxpress.com/news/2018-08-role-protein-immune-dendritic-cells.html Thu, 30 Aug 2018 09:44:12 EDT news454841048 People with major depression that has not been well controlled by medications and who have a biomarker in their blood indicating a higher level of inflammation may benefit more than people with less inflammation from electroconvulsive therapy to ease symptoms of their depression, according to a new UCLA study. https://medicalxpress.com/news/2018-03-inflammation-effectiveness-electroconvulsive-therapy-major.html Tue, 06 Mar 2018 08:55:30 EST news439548907 The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on or off. https://medicalxpress.com/news/2017-08-nutrient-glutamine-gene-cells.html Tue, 15 Aug 2017 12:00:04 EDT news421999915 A new review examines the potential link between psoriasis and mental health conditions. https://medicalxpress.com/news/2017-08-psoriasis-psychiatric-illnesseswhat-links.html Fri, 11 Aug 2017 09:30:17 EDT news421662610