https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. A genetic test developed by researchers at Broad Clinical Labs and the U.S. Department of Veterans Affairs (VA) is now enabling a large, nationwide clinical trial aimed at improving health care for men at increased risk of developing prostate cancer, the second-leading cause of cancer deaths in U.S. men. https://medicalxpress.com/news/2026-02-clinical-trial-explores-genetic-early.html Mon, 09 Feb 2026 16:24:38 EST news689876641 New research appearing in the Journal of the National Comprehensive Cancer Network found that incorporating information from prostate-specific membrane antigen (PSMA) PET/CT scans may be able to predict progression-free survival (PFS) and guide treatment planning in patients with rising prostate-specific antigen (PSA) levels following removal of the prostate. https://medicalxpress.com/news/2026-02-important-recurring-prostate-cancer.html Mon, 09 Feb 2026 09:00:06 EST news689849716 Diagnostic tools based on artificial intelligence are now making their way into Norwegian hospitals. AI can independently read X-ray images and detect bone fractures, or assess cancer tumors in both the breast and prostate. "AI tools can take over the detection of simple and clear-cut cases, allowing doctors to spend their time on more complex ones," said Tone Frost Bathen. She is a professor at NTNU and the project manager of an AI-powered analysis tool for prostate cancer called PROVIZ. https://medicalxpress.com/news/2026-02-ai-tool-prostate-mris-biopsy.html Sat, 07 Feb 2026 09:30:05 EST news689442342 Researchers at the Johns Hopkins Kimmel Cancer Center have developed a novel liquid biopsy approach to identify early-stage cancers by measuring the random variation in DNA methylation patterns, rather than the absolute level of those patterns as in other liquid biopsies. The method, which utilizes a new metric called the Epigenetic Instability Index (EII), successfully distinguished—with high accuracy—patients with early-stage lung and breast cancers from healthy individuals. https://medicalxpress.com/news/2026-02-blood-epigenetic-instability-aids-early.html Mon, 02 Feb 2026 14:42:44 EST news689265722 A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer. This primary analysis of Alliance A222001 is published in the Journal of Clinical Oncology. https://medicalxpress.com/news/2026-01-randomized-trial-drug-therapy-hot.html Mon, 02 Feb 2026 06:00:02 EST news689004481 A team of researchers have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, conducted by researchers from the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, focused on the circadian protein Cryptochrome1 (CRY1), suggests that the time of day when radiotherapy is administered can significantly influence the effectiveness of treatment for certain types of cancer. The paper is published in Nature Communications. https://medicalxpress.com/news/2026-01-radiotherapy-effective-day.html Fri, 30 Jan 2026 08:30:34 EST news688984202 Fifteen prescription medications, including Botox and the diabetes drug Trulicity, will be the focus of federal price negotiations that could lower prices for Medicare patients. https://medicalxpress.com/news/2026-01-medicare-prices-botox-major-drugs.html Thu, 29 Jan 2026 19:10:03 EST news688914594 Telesurgery (operating on a patient remotely using a surgical robot via a secure telecommunication link) appears to be as reliable as standard robotic surgery (when the surgeon and patient are in the same room) for two common urological procedures, suggests a randomized controlled trial from China published in the BMJ today. https://medicalxpress.com/news/2026-01-telesurgery-local-robotic-urological-surgery.html Thu, 29 Jan 2026 13:16:29 EST news688914962 Because treatment of the whole prostate can lead to long-term side effects in patients with prostate cancer, interest in minimally invasive, focal treatment options has been growing for certain patients. A clinical trial published in BJU International generated promising results for a type of focal therapy, which directly targets the cancer and spares the remainder of the unaffected prostate gland. https://medicalxpress.com/news/2026-01-laser-therapy-device-generates-results.html Wed, 28 Jan 2026 03:10:04 EST news688725841 Studies have demonstrated a link between alcohol consumption and an elevated risk of colorectal cancer. New research now reveals that higher lifetime alcohol consumption is also associated with a higher risk, especially for rectal cancer, and that quitting drinking can lower a person's risk. https://medicalxpress.com/news/2026-01-higher-lifetime-alcohol-consumption-linked.html Mon, 26 Jan 2026 03:10:01 EST news688292821 Cancer and Alzheimer's are two of the most common chronic diseases associated with aging. For years, doctors have known about a curious aspect of these two conditions: people who survive cancers are significantly less likely to develop Alzheimer's. While this link has been observed in the data for some time, the biological reasons for it have remained a mystery. Now, a new study published in the journal Cell has discovered a possible explanation. https://medicalxpress.com/news/2026-01-cancer-tumors-alzheimer-protein-clumps.html Sat, 24 Jan 2026 11:30:05 EST news688399824 Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves. https://medicalxpress.com/news/2026-01-tiny-molecules-trna-halves-contribute.html Fri, 23 Jan 2026 14:02:07 EST news688399179 The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers, often allowing less invasive surgery and helping clinicians assess how a patient's cancer responds to medication to guide the most effective treatment options. https://medicalxpress.com/news/2026-01-cancer-medication-surgery.html Thu, 22 Jan 2026 13:03:52 EST news688309382 For many cancer patients, hair loss is one of the most distressing side effects of their therapy. Increasingly, they have been taking oral supplements of biotin, which are marketed to consumers for their potential to improve hair regrowth and brittle nails. https://medicalxpress.com/news/2026-01-cancer-patients-popular-supplement-treatment.html Tue, 20 Jan 2026 15:03:30 EST news688143782 By recognizing patterns in test results, AI can identify patients at risk of cancer, diabetes complications, heart disease and mental health issues. https://medicalxpress.com/news/2026-01-ai-health.html Fri, 16 Jan 2026 01:30:01 EST news687705768 To help meet the potentially complex needs of patients after prostate cancer treatment and offer the precision and care necessary in the follow-up journey, Mayo Clinic's Department of Radiation Oncology developed the PSA Control Tower. This is an intelligent monitoring tool designed to support clinicians in keeping a close, ongoing watch over patients after treatment. https://medicalxpress.com/news/2026-01-prostate-cancer-recurrence-power-ai.html Thu, 15 Jan 2026 09:50:07 EST news687692091 Data from a major U.S. clinical trial from the Alliance for Clinical Trials in Oncology has uncovered a genetic factor that may inform how to optimize the dosing of abiraterone, a widely used hormone treatment for advanced prostate cancer. Published in Clinical and Translational Science, this secondary analysis of Alliance A032201 could lead to more personalized treatments for patients. https://medicalxpress.com/news/2026-01-trial-reveals-gene-variant-affect.html Thu, 15 Jan 2026 09:50:02 EST news687692196 A new long-term prediction tool estimates the risk of dying from prostate cancer, offering a more accurate way to interpret prostate-specific antigen (PSA) test results compared to existing models. The tool, tested on over 200,000 men, outperformed current methods and could help doctors tailor screening and treatment decisions based on individual risk and life expectancy. https://medicalxpress.com/news/2026-01-prostate-cancer-death.html Mon, 12 Jan 2026 17:00:01 EST news687431041 A research team at the University of Würzburg has, for the first time, uncovered how E. coli bacteria sneak into the prostate. The study opens the door to potential new treatments for bacterial prostatitis. https://medicalxpress.com/news/2026-01-uncover-coli-bacteria-prostate.html Mon, 12 Jan 2026 16:30:37 EST news687457802 A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest further development of this approach is merited. https://medicalxpress.com/news/2026-01-genome-sequencing-optimize-parp-inhibitor.html Mon, 12 Jan 2026 16:24:54 EST news687457442 Eating some common food preservatives is linked to a slightly higher risk of eventually developing cancer and diabetes, according to two large French studies published Thursday. https://medicalxpress.com/news/2026-01-food-linked-higher-cancer-diabetes.html Sun, 11 Jan 2026 14:00:02 EST news687091908 Researchers from Children's Hospital of Philadelphia (CHOP) have developed a method to help cancer immunotherapies reach otherwise "invisible" tumors by helping guide therapies to their appropriate targets. This could be particularly useful for very difficult-to-treat tumors like neuroblastoma. The findings appear in Science Advances. https://medicalxpress.com/news/2026-01-protein-complex-immunotherapies-hard-neuroblastoma.html Thu, 08 Jan 2026 16:45:30 EST news687113101 A new study published in Nature Communications provides a framework for researching whether earlier, model-guided treatment intensification can meaningfully improve survival for patients with aggressive disease. https://medicalxpress.com/news/2026-01-easy-tool-high-metastatic-prostate.html Thu, 08 Jan 2026 16:43:04 EST news687112922 A large-scale study has identified dozens of blood proteins linked to prostate cancer risk, some shared across populations, some unique to specific groups. https://medicalxpress.com/news/2026-01-links-dozens-blood-proteins-prostate.html Wed, 07 Jan 2026 17:04:51 EST news687027841 A large team of researchers led by Wouter Karthaus, head of the Endocrine Therapy Resistance and Molecular Genetics Lab at EPFL, and Eneda Toska at Johns Hopkins University have identified the enzyme KMT2D as a key epigenetic regulator in prostate cancer. Their study published in Cancer Research reveals that KMT2D plays a central role in shaping how prostate tumors grow, survive, and respond to therapy. https://medicalxpress.com/news/2026-01-prostate-cancer-code-enzyme-central.html Wed, 07 Jan 2026 15:30:59 EST news687022201 Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy. https://medicalxpress.com/news/2026-01-treatment-advanced-prostate-cancer-severe.html Wed, 07 Jan 2026 09:21:48 EST news687000061 A research team from the Department of Surgery and the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has demonstrated that prostate-specific antigen (PSA) screening for men aged 45 and above can significantly reduce the incidence of advanced-stage prostate cancer from 39% to approximately 1%, and lower the mortality rate from 6.14% to 2.85%. https://medicalxpress.com/news/2026-01-high-effectiveness-prostate-cancer-screening.html Tue, 06 Jan 2026 09:19:33 EST news686913541 For more than 80 years, men have been told that testosterone helps prostate cancer grow. But a very different picture has emerged over the past two decades. https://medicalxpress.com/news/2025-12-testosterone-prostate-cancer-villain-potential.html Mon, 29 Dec 2025 19:20:02 EST news686226646 One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs that are initially effective lose their potency over time, as malignant cells acquire mutations that enable them to survive and spread. https://medicalxpress.com/news/2025-12-cancer-resistance-mutations-immunotherapies.html Mon, 29 Dec 2025 07:37:23 EST news686216199 A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face the highest burden from this disease. The findings were published in the Journal of the National Comprehensive Cancer Network. https://medicalxpress.com/news/2025-12-genomic-flag-early-aggressive-prostate.html Fri, 19 Dec 2025 13:50:01 EST news685374193