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                    <title>Medical Xpress news tagged with:trials</title>
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            <description>Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.</description>

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                    <title>What drives food allergies? New study pinpoints early-life factors that raise risk</title>
                    <description>A new study from McMaster University involving 2.8 million children around the world has revealed the most important early-life factors that influence whether a child becomes allergic to food.</description>
                    <link>https://medicalxpress.com/news/2026-02-food-allergies-early-life-factors.html</link>
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                    <pubDate>Mon, 09 Feb 2026 18:40:06 EST</pubDate>
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                    <title>How immune cells in the adult brain can regulate generation of new neurons</title>
                    <description>A new study, recently published in the journal Nature Communications, is leading to a new understanding of how immune cells can influence adult neurogenesis, the process of creating new neurons in the brain. Neurons are the brain&#039;s fundamental information messengers, and the immune cells conduct surveillance and send messages to new neurons.</description>
                    <link>https://medicalxpress.com/news/2026-02-immune-cells-adult-brain-generation.html</link>
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                    <pubDate>Mon, 09 Feb 2026 16:23:50 EST</pubDate>
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                    <title>Gut-brain discovery identifies harmful bacterial sugar as potential therapeutic target for ALS and dementia</title>
                    <description>A significant discovery by Case Western Reserve University researchers could change how doctors treat two of the most devastating neurodegenerative diseases. The team identified a link between gut bacteria and the deterioration of the brain in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). The researchers discovered that certain bacterial sugars cause immune responses that kill cells—and how to prevent it.</description>
                    <link>https://medicalxpress.com/news/2026-02-gut-brain-discovery-bacterial-sugar.html</link>
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                    <pubDate>Mon, 09 Feb 2026 16:00:03 EST</pubDate>
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                    <title>Video: Cardiologist discusses heart disease in women</title>
                    <description>Heart disease affects women differently than men, and understanding those differences can be lifesaving. Dr. Sharonne N. Hayes, a Mayo Clinic cardiologist and leading expert in the field of women&#039;s heart health, says progress in research, treatment and prevention has accelerated but women still need better information.</description>
                    <link>https://medicalxpress.com/news/2026-02-video-cardiologist-discusses-heart-disease.html</link>
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                    <pubDate>Mon, 09 Feb 2026 11:23:03 EST</pubDate>
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                    <title>Eye cancer genes predetermine liver metastasis, study finds</title>
                    <description>Cells from cancerous tumors can spread, or metastasize, throughout the body. Researchers have long sought to understand what determines where those cells will go and thrive in order to more effectively treat the cancer and prevent metastasis. Researchers at Yale School of Medicine (YSM) have now identified biological markers for a rare, aggressive eye cancer that predict the likelihood of secondary tumors forming in the liver.</description>
                    <link>https://medicalxpress.com/news/2026-02-eye-cancer-genes-predetermine-liver.html</link>
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                    <pubDate>Mon, 09 Feb 2026 09:59:52 EST</pubDate>
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                    <title>Speed-focused brain training tied to 25% lower dementia risk after 20 years</title>
                    <description>A simple brain-training exercise could reduce people&#039;s risk of developing dementia by 25%, a study said Monday, but with outside researchers expressing caution in interpreting the results.</description>
                    <link>https://medicalxpress.com/news/2026-02-focused-brain-dementia-years.html</link>
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                    <pubDate>Mon, 09 Feb 2026 08:47:35 EST</pubDate>
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                    <title>You&#039;ve reached your weight loss goal on GLP-1 medications. What now?</title>
                    <description>GLP-1 drugs have ushered in a new era in weight loss.</description>
                    <link>https://medicalxpress.com/news/2026-02-youve-weight-loss-goal-glp.html</link>
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                    <pubDate>Sat, 07 Feb 2026 14:30:01 EST</pubDate>
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                    <title>Tiny &#039;mini-me&#039; organs grown from children&#039;s cells are transforming cystic fibrosis care</title>
                    <description>When UNSW Associate Professor Shafagh Waters explains cystic fibrosis (CF) to the children she works with, she asks them to imagine what is happening inside their own bodies. &quot;I tell them to picture an airport,&quot; she says. &quot;There&#039;s a gate at the surface of every cell. It&#039;s meant to open so water and salts can flow through—just like planes leaving a gate. In cystic fibrosis, that gate might be stuck closed, built in the wrong place, or it could be so unstable that it falls apart as soon as it forms.&quot;</description>
                    <link>https://medicalxpress.com/news/2026-02-tiny-mini-grown-children-cells.html</link>
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                    <pubDate>Fri, 06 Feb 2026 08:43:37 EST</pubDate>
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                    <title>Australia&#039;s stillbirth prevention program saves lives, shows evaluation</title>
                    <description>Fewer stillbirths and reduced perinatal mortality are the key findings of the first analysis of the Safer Baby Bundle, Australia&#039;s national stillbirth prevention program. The Safer Baby Bundle is a set of evidence-based clinical guidelines and educational resources developed by the Centre of Research Excellence in Stillbirth for clinicians and pregnant women to help prevent the tragedy of stillbirth.</description>
                    <link>https://medicalxpress.com/news/2026-02-australia-stillbirth.html</link>
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                    <pubDate>Thu, 05 Feb 2026 22:00:01 EST</pubDate>
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                    <title>Statins do not cause the majority of side effects listed in package leaflets, large-scale analysis finds</title>
                    <description>Statins do not cause the majority of the conditions that have been listed in their package leaflets, including memory loss, depression, sleep disturbance, and erectile and sexual dysfunction, according to the most comprehensive review of possible side effects. The study was led by researchers at Oxford Population Health and appears in The Lancet.</description>
                    <link>https://medicalxpress.com/news/2026-02-statins-majority-side-effects-package.html</link>
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                    <pubDate>Thu, 05 Feb 2026 18:30:01 EST</pubDate>
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                    <title>Targeting HIV&#039;s hidden reservoirs: Lab-enhanced natural killer cells show promise</title>
                    <description>More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS). The drugs are effective but don&#039;t eliminate the virus; HIV remains hidden in &quot;reservoirs&quot; throughout the body, ready to reactivate if treatment stops.</description>
                    <link>https://medicalxpress.com/news/2026-02-hiv-hidden-reservoirs-lab-natural.html</link>
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                    <pubDate>Thu, 05 Feb 2026 14:55:44 EST</pubDate>
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                    <title>How &#039;invisible&#039; vaccine scaffolding boosts HIV immune response</title>
                    <description>One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus. Then, a person&#039;s immune system produces a range of antibodies that recognize different bits of those proteins. Often, however, some of those antibodies react not to HIV itself, but to the scaffold used to deliver the vaccine.</description>
                    <link>https://medicalxpress.com/news/2026-02-invisible-vaccine-scaffolding-boosts-hiv.html</link>
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                    <pubDate>Thu, 05 Feb 2026 14:00:11 EST</pubDate>
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                    <title>Approved arrhythmia drug may slow MYC-driven lymphoma by blocking USP11 interactions</title>
                    <description>A team of researchers at VCU Massey Comprehensive Cancer Center discovered an innovative way to use a drug already approved for treating irregular heartbeat to selectively target specific functions of enzymes in lymphoma, effectively killing cancer cells and reducing tumor growth with little to no toxicity. Recent findings published in Pharmacological Research set the groundwork for how this strategy could help transform the future of precision medicine in cancer.</description>
                    <link>https://medicalxpress.com/news/2026-02-arrhythmia-drug-myc-driven-lymphoma.html</link>
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                    <pubDate>Thu, 05 Feb 2026 07:00:08 EST</pubDate>
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                    <title>Maternal anemia, erythrocytosis linked to neonatal morbidity and mortality</title>
                    <description>In a high-income setting, maternal anemia and relative erythrocytosis are associated with severe neonatal morbidity and mortality (SNM-M), according to a study published online Feb. 3 in the Annals of Internal Medicine.</description>
                    <link>https://medicalxpress.com/news/2026-02-maternal-anemia-erythrocytosis-linked-neonatal.html</link>
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                    <pubDate>Wed, 04 Feb 2026 17:50:02 EST</pubDate>
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                    <title>Personalized palliative care shows signs of improving quality of life for children with advanced cancer</title>
                    <description>How to reduce suffering in children with advanced cancer remains an ongoing but urgent question. A Mass General Brigham-led study has examined whether systematically surveying children with advanced cancer and their parents about their symptoms and quality of life, providing feedback to children, families, and clinicians—and acting on that information by implementing personalized palliative care—could improve patients&#039; experiences.</description>
                    <link>https://medicalxpress.com/news/2026-02-personalized-palliative-quality-life-children.html</link>
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                    <pubDate>Wed, 04 Feb 2026 16:47:42 EST</pubDate>
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                    <title>A double-edged sword: Chronic cellular stress promotes liver cancer—but also makes tumors vulnerable to immunotherapy</title>
                    <description>A key molecular mechanism drives the growth of liver cell cancer while simultaneously suppressing the body&#039;s immune response to the tumor. This has been published in the journal Nature by a team led by researchers from the German Cancer Research Center (DKFZ), the University Hospital of Tübingen, and the Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California. However, the results also show that this very mechanism could help identify patients who respond particularly well to immunotherapy in the future, thus opening up new therapeutic approaches.</description>
                    <link>https://medicalxpress.com/news/2026-02-edged-sword-chronic-cellular-stress.html</link>
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                    <pubDate>Wed, 04 Feb 2026 11:00:10 EST</pubDate>
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                    <title>New guidance urges faster diagnosis for women under 50 with heart attacks</title>
                    <description>A major global review has revealed critical gaps in how heart attacks in women are diagnosed and treated—particularly for premenopausal women. The American Heart Association (AHA) today released a new scientific statement led by Australian cardiologist Professor Jason Kovacic, warning current clinical practices may be costing women their lives.  The statement is published in the journal Circulation.</description>
                    <link>https://medicalxpress.com/news/2026-02-guidance-urges-faster-diagnosis-women.html</link>
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                    <pubDate>Wed, 04 Feb 2026 10:00:05 EST</pubDate>
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                    <title>Could fecal transplants be the new way to fight cancer?</title>
                    <description>One person&#039;s waste could be another&#039;s shot at fighting cancer. The idea may sound far-fetched, but it is gaining momentum in cancer care. Researchers are testing fecal microbiota transplants as a way of changing the gut&#039;s microbes. This could help treatments, such as immunotherapy, work better, and it could be especially significant for hard-to-reach cancers. These fecal microbiota could also help deliver longer-lasting benefits for more patients.</description>
                    <link>https://medicalxpress.com/news/2026-02-fecal-transplants-cancer.html</link>
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                    <pubDate>Wed, 04 Feb 2026 08:20:02 EST</pubDate>
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                    <title>Grief best managed through talk therapy, evidence shows</title>
                    <description>Talk therapy is the best way to ease grief and depression following the death of a loved one, a new evidence review has concluded.</description>
                    <link>https://medicalxpress.com/news/2026-02-grief-therapy-evidence.html</link>
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                    <pubDate>Tue, 03 Feb 2026 19:40:01 EST</pubDate>
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                    <title>Backward walking study results may help to improve mobility and decrease falls in multiple sclerosis patients</title>
                    <description>A collaborative team of researchers and students from Wayne State University&#039;s Eugene Applebaum College of Pharmacy and Health Sciences, School of Medicine, College of Liberal Arts and Sciences and Institute of Gerontology have studied the impact of a backward walking program on individuals with multiple sclerosis.</description>
                    <link>https://medicalxpress.com/news/2026-02-results-mobility-decrease-falls-multiple.html</link>
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                    <pubDate>Tue, 03 Feb 2026 16:07:58 EST</pubDate>
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                    <title>Sleep medication linked to safer outcomes than antipsychotics for older adults with delirium</title>
                    <description>A large U.S. study suggests that older adults hospitalized with delirium may experience better outcomes when treated with trazodone, commonly used to treat depression and sleep problems, rather than commonly used antipsychotic medications. Delirium, a sudden state of confusion that often affects older adults during or after hospitalization, is frequently treated with medications despite limited evidence about which drugs are safest.</description>
                    <link>https://medicalxpress.com/news/2026-02-medication-linked-safer-outcomes-antipsychotics.html</link>
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                    <pubDate>Tue, 03 Feb 2026 13:34:49 EST</pubDate>
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                    <title>Diabetes management in disadvantaged communities improves significantly with financial incentives, study finds</title>
                    <description>Managing type 2 diabetes is a demanding daily task involving diet, exercise, and often a complex regimen of medications. For patients facing financial hardship, the cost of these life-saving drugs can become a barrier to health, leading many to skip doses or delay refills.</description>
                    <link>https://medicalxpress.com/news/2026-02-diabetes-disadvantaged-communities-significantly-financial.html</link>
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                    <pubDate>Tue, 03 Feb 2026 11:44:34 EST</pubDate>
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                    <title>Study shows strong evidence for effectiveness of metastasis-directed radiation therapy in prostate cancer</title>
                    <description>Metastasis-directed therapy (MDT) significantly improved outcomes in patients with oligometastatic prostate cancer, according to a new study from researchers at The University of Texas MD Anderson Cancer Center published in The Lancet Oncology. The study is a first-of-its-kind meta-analysis of individual patients across all available randomized clinical trials evaluating the addition of metastasis-directed radiation therapy to standard-of-care treatment.</description>
                    <link>https://medicalxpress.com/news/2026-02-strong-evidence-effectiveness-metastasis-therapy.html</link>
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                    <pubDate>Tue, 03 Feb 2026 10:30:51 EST</pubDate>
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                    <title>Clinical data gaps keeping life-saving antibiotics from children</title>
                    <description>Life-saving antibiotics that could treat severe infections in babies and children aren&#039;t accessible due to a lack of data around safety and dosage, new research shows. Two wide sweeping reviews, led by Murdoch Children&#039;s Research Institute (MCRI) and the Australasian KIDS DOSE consortium, have discovered the barriers children are experiencing in Australia, New Zealand and the Pacific Islands when accessing treatment for the antimicrobial resistant (AMR) infections deemed the highest priority by the World Health Organization.</description>
                    <link>https://medicalxpress.com/news/2026-02-clinical-gaps-life-antibiotics-children.html</link>
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                    <pubDate>Tue, 03 Feb 2026 09:28:03 EST</pubDate>
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                    <title>For people with traumatic brain injury and their caregivers, recovery of basic communication is an &#039;acceptable&#039; outcome</title>
                    <description>A study of more than 500 people living with traumatic brain injury (TBI) and their caregivers, co-led by researchers at Mass General Brigham, found that survey participants viewed the ability to regain basic communication as the minimum acceptable outcome after severe brain injury. The study, published in Critical Care Medicine, shows that many individuals living with TBIs consider outcomes involving significant disability to be acceptable. These results challenge longstanding assumptions by TBI researchers and providers about what constitutes a &quot;favorable&quot; outcome after a severe brain injury, and should inform future care discussions and clinical trials, according to the authors.</description>
                    <link>https://medicalxpress.com/news/2026-02-people-traumatic-brain-injury-caregivers.html</link>
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                    <pubDate>Tue, 03 Feb 2026 09:16:38 EST</pubDate>
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                    <title>Use of glucose-lowering SGLT2i drugs may help patients with gout and diabetes take fewer medications</title>
                    <description>Gout, a type of inflammatory arthritis caused by a buildup of uric acid (urate) in the body, affects 5.1% of U.S. adults (over 12 million), including 10% of those aged 65 or older. Urate is produced by the body when breaking down compounds called purines and normally dissolves in the blood, but when levels are high, they can precipitate out as monosodium urate crystals which can deposit in the joints.</description>
                    <link>https://medicalxpress.com/news/2026-02-glucose-lowering-sglt2i-drugs-patients.html</link>
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                    <pubDate>Tue, 03 Feb 2026 07:30:07 EST</pubDate>
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                    <title>Single-shot HIV vaccine candidate induces neutralizing antibodies for the first time</title>
                    <description>Scientists at The Wistar Institute have developed an HIV vaccine candidate that achieves something never before observed in the field: inducing neutralizing antibodies against HIV after a single immunization in nonhuman primates. The innovative approach, published in Nature Immunology, could significantly shorten and simplify HIV vaccination protocols, making them more accessible worldwide.</description>
                    <link>https://medicalxpress.com/news/2026-02-shot-hiv-vaccine-candidate-neutralizing.html</link>
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                    <pubDate>Tue, 03 Feb 2026 06:36:51 EST</pubDate>
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                    <title>Unexpected partial recovery of natural vision observed after intracortical microstimulation in a blind patient</title>
                    <description>A patient with complete blindness caused by irreversible optic nerve damage partially recovered natural vision after participating in a clinical trial of electrical stimulation of the visual cortex conducted by researchers from the Universidad Miguel Hernández de Elche (UMH) and the CIBER in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN). The unexpected improvement was spontaneous, sustained over time, and independent of the implanted device.</description>
                    <link>https://medicalxpress.com/news/2026-02-unexpected-partial-recovery-natural-vision.html</link>
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                    <pubDate>Tue, 03 Feb 2026 02:30:01 EST</pubDate>
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                    <title>A more reliable platform to test antibody medicines</title>
                    <description>An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The work, published in Science Immunology, highlights problems during conventional antibody drug testing and introduces a next-generation mouse model that makes it possible to predict the effects of antibody drugs in humans more accurately.</description>
                    <link>https://medicalxpress.com/news/2026-02-reliable-platform-antibody-medicines.html</link>
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                    <pubDate>Mon, 02 Feb 2026 16:30:31 EST</pubDate>
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                    <title>A &#039;window to the brain&#039;: Chip tracks glioblastoma treatment response using tumor vesicles in blood</title>
                    <description>Technology created at the University of Queensland could improve the odds of surviving brain cancer and change how we treat a range of neurological conditions. Dr. Richard Lobb and Dr. Zhen Zhang from UQ&#039;s Australian Institute for Bioengineering and Nanotechnology have opened a &quot;window to the brain&quot; with a new diagnostic device that can tell how deadly brain tumors respond to treatment from a simple blood test.</description>
                    <link>https://medicalxpress.com/news/2026-02-window-brain-chip-tracks-glioblastoma.html</link>
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                    <pubDate>Mon, 02 Feb 2026 12:17:19 EST</pubDate>
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