https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology A noninvasive DNA blood test can identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are most likely to benefit from 223Ra radiopharmaceutical therapy and monitor their progress throughout treatment, according to new research published in the July issue of The Journal of Nuclear Medicine. Incorporating this approach to DNA profiling into clinical practice has the potential to refine patient selection, enable early detection of treatment resistance and optimize personalized management for patients with prostate cancer. https://medicalxpress.com/news/2026-07-dna-blood-patient-radiopharmaceutical-therapy.html Mon, 20 Jul 2026 12:20:01 EDT news703759490 Australian men are choosing vasectomies in record numbers, with new Adelaide University research revealing a sustained national increase alongside rising cost-of-living pressures and declining birth rates. In the first-of-its-kind study, now posted to the medRxiv preprint server, researchers found that the number of vasectomies performed on men ages 18–44 each year increased by more than 60%, rising from 18,544 procedures in 2016 to 29,848 in 2024. https://medicalxpress.com/news/2026-07-aussie-men-vasectomies-pressures.html Mon, 20 Jul 2026 11:40:05 EDT news703759368 A cross-disciplinary research team led by Hongjie Dai, director of the Materials Institute of Life Sciences and Energy (MILES) at the University of Hong Kong (HKU) in Shenzhen, has developed a promising near-infrared (NIR) fluorescent dye for potential clinical use in ureter imaging during surgical navigation. https://medicalxpress.com/news/2026-07-ureters-stay-visible-hours-dye.html Mon, 13 Jul 2026 11:20:07 EDT news703154731 A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research published in the July issue of The Journal of Nuclear Medicine. Findings from the repeat PSMA scans, which included both local and distant disease, resulted in a change in management for nearly 50% of these patients. https://medicalxpress.com/news/2026-07-prostate-specific-membrane-antigen-pet.html Sat, 11 Jul 2026 10:00:04 EDT news702823706 Researchers at the University of British Columbia have identified a new form of hereditary prostate cancer that, while rare, can cause aggressive disease at a young age. The discovery paves the way for genetic testing programs that could help identify at-risk families and support early cancer detection. https://medicalxpress.com/news/2026-07-hereditary-prostate-cancer.html Thu, 09 Jul 2026 15:20:05 EDT news702816841 In the United States, prostate cancer is a leading cause of cancer-related disease and death in men. About half of prostate cancer cases in patients of European ancestry have a gene rearrangement in which the genes TMPRSS2 and ERG are fused together. This causes the ERG protein to be turned on, increasing the growth and migration of tumor cells. However, ERG has been considered undruggable because it lacks the usual pockets that a drug can bind to. https://medicalxpress.com/news/2026-07-hidden-pocket-reveals-prostate-cancer.html Thu, 09 Jul 2026 15:20:01 EDT news702823022 A new cancer drug may be able to inhibit both tumor growth and the spread of aggressive prostate cancer. This is shown in a study conducted by researchers at Umeå University together with international collaborators, published in the journal Signal Transduction and Targeted Therapy. https://medicalxpress.com/news/2026-07-drug-metastatic-prostate-cancer-human.html Tue, 07 Jul 2026 21:40:04 EDT news702638917 One in three men will experience moderate to severe lower urinary tract symptoms in their lifetime, with symptoms including frequent urination, difficulty starting urination, nocturia and a weak urine stream. Although these are common symptoms, in older men they can significantly affect quality of life. https://medicalxpress.com/news/2026-07-older-men-reassess-term-prostate.html Tue, 07 Jul 2026 14:40:06 EDT news702646261 For patients with clear-cell renal cell carcinoma, pembrolizumab-belzutifan yields significantly higher disease-free survival, according to a study published in the July 2 issue of the New England Journal of Medicine. https://medicalxpress.com/news/2026-07-pembrolizumab-belzutifan-disease-free-survival.html Mon, 06 Jul 2026 23:00:01 EDT news702562799 New research presented at the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) suggests that exposure to air pollution may affect genes associated with sperm development, raising new questions about male fertility, pregnancy outcomes and offspring health. The study was published in Human Reproduction. https://medicalxpress.com/news/2026-07-air-pollution-sperm-genes-function.html Mon, 06 Jul 2026 19:00:05 EDT news702539391 Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy. The study, published in the journal Human Reproduction Open, may eventually contribute to new ways of protecting and restoring fertility after childhood cancer. https://medicalxpress.com/news/2026-07-testicular-tissue-early-germ-cells.html Thu, 02 Jul 2026 18:40:01 EDT news702204548 A growing number of prostate cancer experts argue that calling the lowest-risk prostate cancer "cancer" does more harm than good. A new UCLA-led study found removing the cancer label could dramatically reduce overtreatment and encourage more men to get screened, potentially leading to significantly fewer deaths from aggressive prostate cancer. https://medicalxpress.com/news/2026-07-lowest-prostate-cancer.html Wed, 01 Jul 2026 16:00:11 EDT news702131221 The first-in-patient, single-arm ARC-20 clinical trial, led by Dana-Farber Cancer Institute's Toni K. Choueiri, MD, has evaluated casdatifan, a next-generation HIF-2α inhibitor, as monotherapy for metastatic clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer. Patients eligible for the study were previously treated with standard therapies. https://medicalxpress.com/news/2026-06-generation-hif-inhibitor-kidney-cancer.html Wed, 01 Jul 2026 11:00:16 EDT news702048243 The prostate is the single organ most frequently afflicted by cancer in men. Prostate cancer affects approximately 4 million American men, with another 330,000 men expected to be diagnosed with the condition this year alone. https://medicalxpress.com/news/2026-07-dna-methylation-patterns-prostate-cancers.html Wed, 01 Jul 2026 07:40:02 EDT news702101821 For patients with benign prostatic hyperplasia (BPH), early functional outcomes are comparable with high-peak-power pulsed Thulium:YAG laser enucleation (p-ThuLEP) and open simple prostatectomy (OSP), but shorter hospitalization and lower transfusion rates are seen with p-ThuLEP, according to a study published online May 30 in Translational Andrology and Urology. https://medicalxpress.com/news/2026-06-early-benign-prostatic-hyperplasia-outcomes.html Tue, 30 Jun 2026 19:20:01 EDT news702053743 New research suggests that low handgrip strength alone is not a reliable predictor of increased prostate cancer risk among older men. The relationship between low handgrip strength (HGS) and prostate cancer has long remained uncertain in the scientific literature. When clinicians consider grip strength as a possible indicator, they are often extrapolating from broader cancer research rather than relying on direct evidence. https://medicalxpress.com/news/2026-06-strength-independent-predictor-prostate-cancer.html Mon, 29 Jun 2026 11:00:03 EDT news701945995 Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, published in the Journal of Experimental Medicine (JEM), demonstrates that direct delivery of these CAR T cells via a catheter can control bladder tumors in mice, raising hopes that a similar approach may be effective in humans. https://medicalxpress.com/news/2026-06-intravesical-car-therapy-door-bladder.html Fri, 26 Jun 2026 10:00:06 EDT news701596381 When high-profile figures publicly discuss their prostate cancer, the public health impact can be immediate. The media coverage raises awareness. More men may seek information or medical advice. https://medicalxpress.com/news/2026-06-celebrities-prostate-cancer.html Fri, 26 Jun 2026 08:40:01 EDT news701673841 There is a significant association between hepatitis C virus (HCV) and overactive bladder (OAB), according to a study published online May 29 in BMC Urology. https://medicalxpress.com/news/2026-06-significant-association-hepatitis-overactive-bladder.html Thu, 25 Jun 2026 16:20:01 EDT news701612791 Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm. The new method enables a detailed analysis even with small samples and allows the detection of the largest number of potential biomarkers identified to date; this advance could help diagnose male infertility and develop future clinical solutions. The paper is published in the journal Cells. https://medicalxpress.com/news/2026-06-methodology-biomarkers-male-infertility.html Thu, 25 Jun 2026 11:20:01 EDT news701603238 The burning pain associated with cystitis affects millions of people around the world, and it can take days or even years for some patients to find relief from bladder pain, infection-related symptoms and the constant need to urinate. A new study led by Flinders University published in Autonomic Neuroscience, has shown how certain pain receptors in the bladder could be targeted to reduce the debilitating effects of this common condition. https://medicalxpress.com/news/2026-06-cannabinoid-receptors-bladder-sensory-pathways.html Thu, 25 Jun 2026 09:20:07 EDT news701594041 The first-in-human fully vascularized bladder graft transplanted with a kidney has reached a promising six-month milestone, according to a new feasibility study published in The Lancet. The procedure, performed in May 2025, demonstrated technical feasibility and early functional success at six months after surgery. https://medicalxpress.com/news/2026-06-month-results-feasibility-early-success.html Wed, 24 Jun 2026 09:20:08 EDT news701511022 The U.S. Food and Drug Administration has approved GSK's Utebzi (tebipenem pivoxil), an oral antibiotic, for the treatment of complicated urinary tract infections (cUTIs). https://medicalxpress.com/news/2026-06-fda-oral-utebzi-antibiotic-complicated.html Tue, 23 Jun 2026 20:40:03 EDT news701418988 The U.S. Food and Drug Administration (FDA) is asking drugmakers to update the prescribing information on testosterone replacement therapy products to reflect newer clinical evidence. https://medicalxpress.com/news/2026-06-testosterone-therapy-limits-fda.html Tue, 23 Jun 2026 18:00:01 EDT news701447607 A new blood test may make it easier to detect the most dangerous forms of prostate cancer early. In a study from Karolinska Institutet, the Stockholm3 blood test detected more clinically significant cancer cases than the PSA test, without subjecting more men to unnecessary testing. The study is published in the Annals of Internal Medicine. https://medicalxpress.com/news/2026-06-blood-high-prostate-cancer-cases.html Tue, 23 Jun 2026 12:00:01 EDT news701432549 The U.S. Food and Drug Administration has approved Merck's Welireg (belzutifan) in combination with pembrolizumab or pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex) for the adjuvant treatment of renal cell carcinoma in adults with a clear cell component at intermediate-high or high risk for recurrence following nephrectomy, or following nephrectomy and resection of metastatic lesions. https://medicalxpress.com/news/2026-06-fda-welireg-pembrolizumab-renal-cell.html Fri, 19 Jun 2026 18:20:01 EDT news701074857 UK media celebrity Jeremy Clarkson this week revealed he has been diagnosed with an aggressive form of prostate cancer. https://medicalxpress.com/news/2026-06-jeremy-clarkson-aggressive-prostate-cancer.html Thu, 18 Jun 2026 23:20:02 EDT news701010690 Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic vulnerabilities are organized within tumors. The study, published in Cancer Discovery, provides a new framework for understanding why patients with bladder cancer may respond differently to treatment. https://medicalxpress.com/news/2026-06-spatial-bladder-cancer-reveals-hidden.html Thu, 18 Jun 2026 15:20:06 EDT news701010795 Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression. https://medicalxpress.com/news/2026-06-hidden-pim1-pathway-prostate-cancer.html Tue, 16 Jun 2026 15:20:03 EDT news700838188 Many medicines begin life with one purpose and end up proving useful for a completely different reason. https://medicalxpress.com/news/2026-06-men-health-drugs-purpose.html Tue, 16 Jun 2026 11:40:03 EDT news700824782