https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology Prostate cancer screening is one of the most common decisions men face in primary care, yet many patients make that choice without fully understanding the potential benefits and harms. A new editorial by UNC physician experts argues that shared decision-making should no longer depend on individual clinician effort but instead be built into health care systems. https://medicalxpress.com/news/2026-06-physician-experts-based-approach-prostate.html Thu, 04 Jun 2026 12:40:04 EDT news699793561 The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. Results from a study in the Journal of Internal Medicine suggest that this may prompt a clinician to run tests to uncover an asymptomatic bladder tumor. https://medicalxpress.com/news/2026-06-aspirin-unmask-silent-bladder-cancer.html Wed, 03 Jun 2026 03:10:01 EDT news699611881 Results of a multicenter clinical trial found that adding the investigational adenoviral-based viral immunotherapy aglatimagene besadenovec (alglatimagene, CAN-2409) to standard radiation therapy improved disease-free survival for patients with intermediate- or high-risk localized prostate cancer. The study was led by researchers at the Johns Hopkins University School of Medicine, Johns Hopkins Kimmel Cancer Center, Department of Radiation Oncology and Molecular Radiation Sciences, and Brady Urological Institute. Findings from the study were published June 1 in The Lancet Oncology. https://medicalxpress.com/news/2026-06-immunotherapy-added-therapy-boosts-survival.html Tue, 02 Jun 2026 16:40:05 EDT news699629521 The Society of Interventional Radiology (SIR) has published new practice guidance for the use of prostatic artery embolization (PAE) to treat enlarged prostate (also called benign prostatic hyperplasia or BPH). The guidance appears in the Journal of Vascular and Interventional Radiology to coincide with the start of Men's Health Month in June. https://medicalxpress.com/news/2026-06-guidance-treatment-enlarged-prostate.html Tue, 02 Jun 2026 15:30:01 EDT news699631562 A novel theranostic approach that targets RET—a newly identified biomarker for neuroendocrine prostate cancer—enables high-contrast PET imaging and effective, safe treatment for this highly aggressive malignancy. Because this disease is often poorly visualized with prostate-specific membrane antigen (PSMA)-based imaging, the RET approach offers an important alternative when conventional molecular imaging and PSMA-directed therapies are unsuitable. This research is being presented at the Society of Nuclear Medicine and Molecular Imaging 2026 Annual Meeting. https://medicalxpress.com/news/2026-06-theranostic-approach-effectively-neuroendocrine-prostate.html Tue, 02 Jun 2026 13:50:01 EDT news699544981 A Phase III clinical trial led by Neeraj Agarwal, MD, FASCO, senior director of clinical research at Huntsman Cancer Institute and professor of internal medicine at the University of Utah (the U), has found that a combination prostate cancer treatment could prevent the disease from progressing into a harder-to-treat form of cancer in select patients. https://medicalxpress.com/news/2026-06-prostate-cancer-treatment-disease-clinical.html Tue, 02 Jun 2026 13:00:01 EDT news699618781 The largest real-world study ever conducted on prostate cancer in Brazil analyzed data from 670,205 patients treated through the Brazilian Unified Health System (SUS) over a 16-year period, between 2008 and 2023. Published in the Journal of Global Oncology, the study included researchers from the D'Or Institute for Research and Education (IDOR) and investigated patterns of diagnosis, treatment, and health care costs related to the disease across the country. The results revealed significant racial inequalities, including a higher frequency of advanced disease at diagnosis among non-white men and differences in therapeutic investment. https://medicalxpress.com/news/2026-06-prostate-cancer-brazil-reveals-racial.html Mon, 01 Jun 2026 22:00:01 EDT news699547599 High-risk localized and locally advanced prostate cancer patients treated with apalutamide—a next generation neoadjuvant androgen-receptor pathway inhibitor (ARPI)—plus hormone therapy before and after prostate cancer surgery resulted in more major pathologic responses and reduced the risk of metastasis or death, meeting both primary endpoints, in an international Phase III clinical trial led by principal investigator Mary-Ellen Taplin, MD, medical oncologist at Dana-Farber Cancer Institute, and Adam Kibel, MD, chair of the Department of Urology at Mass General Brigham. https://medicalxpress.com/news/2026-06-perioperative-apalutamide-high-localized-locally.html Mon, 01 Jun 2026 07:40:01 EDT news699509702 Problematic media use is associated with sleep disturbances in children diagnosed with enuresis, according to a study published in the August issue of the Journal of Pediatric Urology. https://medicalxpress.com/news/2026-05-problematic-media-linked-disturbances-children.html Thu, 28 May 2026 16:00:02 EDT news699192822 Both robot-assisted simple prostatectomy (RASP) and laser enucleation of the prostate (LEP) are safe and effective surgical options for large-volume benign prostatic hyperplasia (BPH), according to a review published online May 4 in Frontiers in Medicine. https://medicalxpress.com/news/2026-05-robot-simple-prostatectomy-laser-enucleation.html Thu, 28 May 2026 15:20:06 EDT news699192834 Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease. The study published in the Journal of Experimental Medicine (JEM), shows that genetic or pharmacological inhibition of Sirtuin 1 prevents the growth of NEPC tumors in mice, and lays the groundwork for future clinical studies aimed at developing new treatments for NEPC in humans. https://medicalxpress.com/news/2026-05-aggressive-prostate-cancer.html Thu, 28 May 2026 10:00:05 EDT news699092599 The effects of cannabis on the hormonal system and male fertility remain controversial within the scientific community. A study conducted by the University of Geneva (UNIGE), in collaboration with the Swiss Center for Applied Human Toxicology (SCAHT), provides a new answer by showing that cannabis use does not reduce testosterone levels in young men and may even increase its testicular synthesis. https://medicalxpress.com/news/2026-05-cannabis-testosterone.html Thu, 28 May 2026 08:40:01 EDT news699175982 After nearly two decades of life-threatening illness, repeated complications, and organ failure, 33-year-old Briana Dery of Twining, Mich., is looking ahead to a healthy future, after successfully undergoing one of the rarest and most complex procedures in modern medicine. On January 14, 2026, she became the first person in Michigan to receive a new intestinal transplant and a new kidney in a single combined transplant operation. https://medicalxpress.com/news/2026-05-combined-intestinal-kidney-transplant.html Wed, 27 May 2026 21:40:01 EDT news699092403 Ceramides—lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death—and their metabolites have been implicated in the development of cancer and other conditions. New research indicates that different ceramide metabolism in Black and white individuals with metastatic castration-resistant prostate cancer may help explain why they tend to experience different responses to anti-prostate cancer androgen receptor pathway blocking medications. https://medicalxpress.com/news/2026-05-ceramide-lipid-metabolism-affect-response.html Tue, 26 May 2026 03:00:01 EDT news698914483 Low-frequency contralesional repetitive transcranial magnetic stimulation (rTMS) is effective and safe for poststroke neurogenic overactive bladder (OAB), according to a study published in Neurorehabilitation & Neural Repair. https://medicalxpress.com/news/2026-05-repetitive-tms-effective-safe-poststroke.html Mon, 25 May 2026 17:20:01 EDT news698914507 Researchers with the James P. Allison Institute at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment. https://medicalxpress.com/news/2026-05-marker-patients-advanced-prostate-cancer.html Thu, 21 May 2026 09:20:03 EDT news698572854 Reusable catheters are just as safe for patients as single-use ones and do not increase the risk of urinary tract infections, a new study has found. https://medicalxpress.com/news/2026-05-reusable-catheters-safe-choice-antibiotic.html Wed, 20 May 2026 19:10:01 EDT news698511301 A new blood test could help doctors identify whether a treatment for advanced prostate cancer is failing weeks earlier than current tests, according to a U.K.-wide study led by UCL researchers. The study, published in Nature Cancer, shows that men could switch or intensify treatment much sooner than is currently possible if their cancer is not responding to treatment, potentially saving precious time and improving outcomes for patients. https://medicalxpress.com/news/2026-05-blood-prostate-cancer-treatment-weeks.html Mon, 18 May 2026 16:00:05 EDT news698335482 A new study may pave the way toward more personalized treatments for patients with high-risk bladder cancer, according to a study published in European Urology. https://medicalxpress.com/news/2026-05-treatment-response-high-bladder-cancer.html Mon, 18 May 2026 07:20:01 EDT news698306642 Two larger doses of radiotherapy for prostate cancer cause no additional side effects compared to the standard five doses of radiotherapy, according to results presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026). Experts say the research brings us one step closer to safe and effective radiotherapy in only two out-patient sessions. https://medicalxpress.com/news/2026-05-radiotherapy-sessions-days-prostate-cancer.html Sun, 17 May 2026 08:10:01 EDT news697989481 For men with advanced prostate cancer that no longer responds to standard hormone therapies, treatment options are limited—and time matters. As the disease progresses, the window for effective, less intensive treatments begins to close. A multi-institutional clinical trial led by researchers at the Medical University of South Carolina (MUSC) and Emory University tested whether an experimental drug could extend the effectiveness of existing therapies. https://medicalxpress.com/news/2026-05-experimental-drug-patients-advanced-prostate.html Fri, 15 May 2026 14:00:03 EDT news698070121 Blood tests to detect potential signs of prostate cancer likely reduce the risk of dying from prostate cancer, an updated review finds. This is a shift from the previous version of the review, which did not find sufficient evidence that screening reduced prostate cancer deaths. The update appears in the Cochrane Database of Systematic Reviews. https://medicalxpress.com/news/2026-05-screening-modestly-prostate-cancer-deaths.html Thu, 14 May 2026 20:00:04 EDT news697968061 Combining two widely prescribed drug classes could provide the first effective treatment for early-stage Peyronie's disease, according to a new study published in The Journal of Sexual Medicine. https://medicalxpress.com/news/2026-05-viagra-key-halting-peyronie-disease.html Thu, 14 May 2026 19:10:01 EDT news697966741 The FOXA1 protein is a potentially highly sensitive diagnostic marker for small cell carcinoma of the prostate and possibly other aggressive prostate cancer subtypes that are difficult to diagnose due to a loss of traditional prostatic markers, according to researchers at The University of Texas MD Anderson Cancer Center. The study, published in Histopathology, was led by Jianping Zhao, M.D., Ph.D., assistant professor of Anatomic Pathology. https://medicalxpress.com/news/2026-05-diagnostic-marker-aids-diagnosis-aggressive.html Thu, 14 May 2026 15:35:08 EDT news697991642 A new Phase I clinical trial provides proof of concept for a potential therapy for treatment-resistant cancers, particularly kidney cancer. In the new study, published in Cell Reports Medicine, researchers tested a novel kind of immunotherapy in individuals with different types of cancer. https://medicalxpress.com/news/2026-05-experimental-drug-advanced-kidney-tumors.html Thu, 14 May 2026 13:00:01 EDT news697982393 Most prostate cancers rely on male sex hormones, known as androgens, to grow. As a result, standard treatment focuses on lowering androgen levels or blocking their activity, but many tumors eventually become resistant and the disease returns. https://medicalxpress.com/news/2026-05-molecular-marker-prostate-cancer-treatment.html Tue, 12 May 2026 15:20:04 EDT news697814522 Researchers at Moffitt Cancer Center report encouraging early results from a phase 2 study examining whether immunotherapy can improve results when added to a radiotherapy-based treatment regimen for men with aggressive prostate cancer. The work, led by Kosj Yamoah, MD, Ph.D., was published in the Journal for ImmunoTherapy of Cancer. https://medicalxpress.com/news/2026-05-immunotherapy-treatment-aggressive-prostate-cancer.html Tue, 12 May 2026 10:20:02 EDT news697799282 Most men with low-grade prostate cancer have an excellent prognosis, with a five-year survival rate of more than 99%. But radical prostatectomy—surgery to remove the prostate—can lead to sexual and physical dysfunction, fatigue, and low mood. A randomized clinical trial led by Shalender Bhasin, MBBS, of the Division of Endocrinology, Diabetes, and Hypertension in the Mass General Brigham Department of Medicine has investigated whether testosterone replacement therapy (TRT) could improve these symptoms. https://medicalxpress.com/news/2026-05-testosterone-treatment-sexual-physical-function.html Mon, 11 May 2026 19:00:01 EDT news697733822 Surgery is a complicated endeavor. Even a successful surgery can lead to complications, and even the best surgeons sometimes have unsuccessful surgeries. A surgeon must rely on visual cues and their own experience to avoid hitting a nerve or a blood vessel, mistakes that can turn a simple surgery into a much more challenging one. https://medicalxpress.com/news/2026-05-laser-acoustic-imaging-hidden-nerves.html Mon, 11 May 2026 08:40:01 EDT news697359330 A new urine test performed better than PSA-based testing and MRI for monitoring low-risk prostate cancers on active surveillance. Use of the test to determine the need for repeat "monitoring" biopsies would have avoided up to 64% of unnecessary biopsies while maintaining timely detection of higher-grade cancers that merit treatment, according to a study published in The Journal of Urology. https://medicalxpress.com/news/2026-05-urine-outperforms-mri-prostate-cancer.html Fri, 08 May 2026 13:40:09 EDT news697464481