https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer—such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles—after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation. https://medicalxpress.com/news/2026-08-traditional-prostate-cancer-factors-hormone.html Mon, 10 Aug 2026 17:20:06 EDT news705600421 A nationwide Veterans Affairs (VA) study comparing two leading treatments for metastatic prostate cancer may help doctors choose the right drug for each patient, said a Rutgers Cancer Institute physician-scientist whose invited editorial accompanies the research. https://medicalxpress.com/news/2026-08-veterans-affairs-prostate-cancer-treatment.html Mon, 10 Aug 2026 11:40:01 EDT news705580381 After treatment for metastatic prostate cancer, a drop in prostate-specific antigen (PSA) levels in the blood is an indicator that treatment is working. A recent real-world study indicates that reaching a PSA level below 0.2 ng/mL is an indicator of improved patient survival. The study is published online in CANCER. https://medicalxpress.com/news/2026-08-prostate-cancer-prognosis-linked-specific.html Mon, 10 Aug 2026 03:10:01 EDT news705243845 Earlier use of a targeted radionuclide therapy delays metastatic prostate cancer progression when administered as part of a trio of drugs, according to a Phase III clinical trial led by Weill Cornell Medicine, NewYork-Presbyterian, Memorial Sloan Kettering Cancer Center and investigators at several other institutions worldwide. https://medicalxpress.com/news/2026-08-radiopharmaceutical-benefit-patients-metastatic-prostate.html Fri, 07 Aug 2026 13:20:05 EDT news705324093 An imbalance in the bacteria found in men's semen was linked to substantially lower chances of a couple having a baby and to more pregnancy losses, according to new research published in The Lancet Obstetrics, Gynaecology, & Women's Health. This association between semen bacteria and birth outcomes was seen among couples undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) fertility treatment, as well as among women with recurrent pregnancy loss. https://medicalxpress.com/news/2026-08-bacterial-imbalance-men-semen-chances.html Wed, 05 Aug 2026 10:40:04 EDT news705138720 Aboriginal and Torres Strait Islander men diagnosed with prostate cancer are less likely to receive surgery than other Australian men and more likely to face financial barriers to treatment, according to the largest Australian study of its kind. https://medicalxpress.com/news/2026-08-access-barriers-aboriginal-men-prostate.html Tue, 04 Aug 2026 22:20:01 EDT news705065881 An erectile dysfunction drug that is also used to treat symptoms, such as sudden urgency and frequency, associated with an enlarged prostate in men may heighten the risk of glaucoma, a serious eye condition, a large comparative study published online in the British Journal of Ophthalmology finds. https://medicalxpress.com/news/2026-08-erectile-dysfunction-drug-enlarged-prostate.html Tue, 04 Aug 2026 18:30:01 EDT news704965160 UCLA researchers have identified a promising strategy to make a new class of targeted cancer therapies more effective against one of the deadliest forms of prostate cancer, potentially overcoming treatment resistance that has limited their success. https://medicalxpress.com/news/2026-08-combination-therapies-treatment-resistance-advanced.html Tue, 04 Aug 2026 13:00:10 EDT news705062642 Australian researchers have discovered a previously overlooked group of bladder nerves that help detect urinary tract infections (UTIs) and trigger the body's response to clear them, providing a potential new target for future bladder pain therapies. https://medicalxpress.com/news/2026-08-uti-good.html Tue, 04 Aug 2026 12:40:03 EDT news705062341 For patients with interstitial cystitis (IC)/bladder pain syndrome (BPS), the combination of platelet-rich plasma (PRP) and low-intensity extracorporeal shock wave therapy (LI-ESWT) shows therapeutic efficacy, according to a study recently published in Frontiers in Bioengineering and Biotechnology. https://medicalxpress.com/news/2026-07-platelet-rich-plasma-shockwave-therapy.html Fri, 31 Jul 2026 15:40:02 EDT news704719870 Men aged 50 years and older demonstrate insufficient knowledge, a positive attitude and proactive practices regarding benign prostatic hyperplasia (BPH), according to a study published online July 17 in Neurourology and Urodynamics. https://medicalxpress.com/news/2026-07-men-years-older-insufficient-knowledge.html Thu, 30 Jul 2026 16:00:03 EDT news704634461 Recurrent urinary tract infections (rUTIs) are among the most common bacterial infections worldwide and primarily affect women. While antibiotics remain the standard treatment, frequent recurrences and rising antibiotic resistance highlight the need for alternative therapeutic approaches such as phage therapy. Phages are tiny viruses that selectively target bacteria and can effectively destroy even multidrug-resistant bacteria. https://medicalxpress.com/news/2026-07-phage-microbiota-therapy-recurrent-utis.html Thu, 30 Jul 2026 10:00:08 EDT news704622065 Weaker rest-activity rhythms (RARs) and unfavorable sleep profiles are associated with a higher prevalence of overactive bladder (OAB), according to a study published online July 17 in Neurourology and Urodynamics. https://medicalxpress.com/news/2026-07-weaker-rest-rhythm-unfavorable-profile.html Tue, 28 Jul 2026 23:20:01 EDT news704463853 A Mayo Clinic-led international phase 3 study found that a new immunotherapy helped many patients with an aggressive form of bladder cancer keep their bladder instead of having it surgically removed. The treatment also kept many patients cancer-free for more than two years and caused mostly mild side effects. The findings were published in The Lancet Oncology. https://medicalxpress.com/news/2026-07-experimental-immunotherapy-patients-high-bladder.html Tue, 28 Jul 2026 13:20:07 EDT news704461261 The movements of a surgeon in a procedure—called "surgical gestures"—can be used to predict patient recovery, according to Cedars-Sinai investigators. Their findings, published in npj Digital Medicine, suggest this technology could help surgeons refine their techniques and improve patient outcomes. https://medicalxpress.com/news/2026-07-ai-surgical-technique-prostate-cancer.html Sun, 26 Jul 2026 12:00:04 EDT news704108972 Researchers have found that a combination of enfortumab vedotin and pembrolizumab helps patients with muscle-invasive bladder cancer live longer while reducing the risk that their cancer will return after surgery, according to an international phase 3 clinical trial published in The New England Journal of Medicine. https://medicalxpress.com/news/2026-07-treatment-approach-survival-recurrence-muscle.html Fri, 24 Jul 2026 12:00:05 EDT news704104859 New research from the University of South Alabama is shedding light on an emerging bacterial cause of urinary tract infections (UTIs) that appears to be more common along the Gulf Coast than previously recognized. https://medicalxpress.com/news/2026-07-previously-unknown-pseudomonas-strains-emerge.html Fri, 24 Jul 2026 07:00:03 EDT news704086921 A noninvasive DNA blood test can identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are most likely to benefit from 223Ra radiopharmaceutical therapy and monitor their progress throughout treatment, according to new research published in the July issue of The Journal of Nuclear Medicine. Incorporating this approach to DNA profiling into clinical practice has the potential to refine patient selection, enable early detection of treatment resistance and optimize personalized management for patients with prostate cancer. https://medicalxpress.com/news/2026-07-dna-blood-patient-radiopharmaceutical-therapy.html Mon, 20 Jul 2026 12:20:01 EDT news703759490 Australian men are choosing vasectomies in record numbers, with new Adelaide University research revealing a sustained national increase alongside rising cost-of-living pressures and declining birth rates. In the first-of-its-kind study, now posted to the medRxiv preprint server, researchers found that the number of vasectomies performed on men ages 18–44 each year increased by more than 60%, rising from 18,544 procedures in 2016 to 29,848 in 2024. https://medicalxpress.com/news/2026-07-aussie-men-vasectomies-pressures.html Mon, 20 Jul 2026 11:40:05 EDT news703759368 A cross-disciplinary research team led by Hongjie Dai, director of the Materials Institute of Life Sciences and Energy (MILES) at the University of Hong Kong (HKU) in Shenzhen, has developed a promising near-infrared (NIR) fluorescent dye for potential clinical use in ureter imaging during surgical navigation. https://medicalxpress.com/news/2026-07-ureters-stay-visible-hours-dye.html Mon, 13 Jul 2026 11:20:07 EDT news703154731 A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of patients whose first scan was negative, according to new research published in the July issue of The Journal of Nuclear Medicine. Findings from the repeat PSMA scans, which included both local and distant disease, resulted in a change in management for nearly 50% of these patients. https://medicalxpress.com/news/2026-07-prostate-specific-membrane-antigen-pet.html Sat, 11 Jul 2026 10:00:04 EDT news702823706 Researchers at the University of British Columbia have identified a new form of hereditary prostate cancer that, while rare, can cause aggressive disease at a young age. The discovery paves the way for genetic testing programs that could help identify at-risk families and support early cancer detection. https://medicalxpress.com/news/2026-07-hereditary-prostate-cancer.html Thu, 09 Jul 2026 15:20:05 EDT news702816841 In the United States, prostate cancer is a leading cause of cancer-related disease and death in men. About half of prostate cancer cases in patients of European ancestry have a gene rearrangement in which the genes TMPRSS2 and ERG are fused together. This causes the ERG protein to be turned on, increasing the growth and migration of tumor cells. However, ERG has been considered undruggable because it lacks the usual pockets that a drug can bind to. https://medicalxpress.com/news/2026-07-hidden-pocket-reveals-prostate-cancer.html Thu, 09 Jul 2026 15:20:01 EDT news702823022 A new cancer drug may be able to inhibit both tumor growth and the spread of aggressive prostate cancer. This is shown in a study conducted by researchers at Umeå University together with international collaborators, published in the journal Signal Transduction and Targeted Therapy. https://medicalxpress.com/news/2026-07-drug-metastatic-prostate-cancer-human.html Tue, 07 Jul 2026 21:40:04 EDT news702638917 One in three men will experience moderate to severe lower urinary tract symptoms in their lifetime, with symptoms including frequent urination, difficulty starting urination, nocturia and a weak urine stream. Although these are common symptoms, in older men they can significantly affect quality of life. https://medicalxpress.com/news/2026-07-older-men-reassess-term-prostate.html Tue, 07 Jul 2026 14:40:06 EDT news702646261 For patients with clear-cell renal cell carcinoma, pembrolizumab-belzutifan yields significantly higher disease-free survival, according to a study published in the July 2 issue of the New England Journal of Medicine. https://medicalxpress.com/news/2026-07-pembrolizumab-belzutifan-disease-free-survival.html Mon, 06 Jul 2026 23:00:01 EDT news702562799 New research presented at the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) suggests that exposure to air pollution may affect genes associated with sperm development, raising new questions about male fertility, pregnancy outcomes and offspring health. The study was published in Human Reproduction. https://medicalxpress.com/news/2026-07-air-pollution-sperm-genes-function.html Mon, 06 Jul 2026 19:00:05 EDT news702539391 Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy. The study, published in the journal Human Reproduction Open, may eventually contribute to new ways of protecting and restoring fertility after childhood cancer. https://medicalxpress.com/news/2026-07-testicular-tissue-early-germ-cells.html Thu, 02 Jul 2026 18:40:01 EDT news702204548 A growing number of prostate cancer experts argue that calling the lowest-risk prostate cancer "cancer" does more harm than good. A new UCLA-led study found removing the cancer label could dramatically reduce overtreatment and encourage more men to get screened, potentially leading to significantly fewer deaths from aggressive prostate cancer. https://medicalxpress.com/news/2026-07-lowest-prostate-cancer.html Wed, 01 Jul 2026 16:00:11 EDT news702131221 The first-in-patient, single-arm ARC-20 clinical trial, led by Dana-Farber Cancer Institute's Toni K. Choueiri, MD, has evaluated casdatifan, a next-generation HIF-2α inhibitor, as monotherapy for metastatic clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer. Patients eligible for the study were previously treated with standard therapies. https://medicalxpress.com/news/2026-06-generation-hif-inhibitor-kidney-cancer.html Wed, 01 Jul 2026 11:00:16 EDT news702048243