https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology A growing number of prostate cancer experts argue that calling the lowest-risk prostate cancer "cancer" does more harm than good. A new UCLA-led study found removing the cancer label could dramatically reduce overtreatment and encourage more men to get screened, potentially leading to significantly fewer deaths from aggressive prostate cancer. https://medicalxpress.com/news/2026-07-lowest-prostate-cancer.html Wed, 01 Jul 2026 16:00:11 EDT news702131221 The first-in-patient, single-arm ARC-20 clinical trial, led by Dana-Farber Cancer Institute's Toni K. Choueiri, MD, has evaluated casdatifan, a next-generation HIF-2α inhibitor, as monotherapy for metastatic clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer. Patients eligible for the study were previously treated with standard therapies. https://medicalxpress.com/news/2026-06-generation-hif-inhibitor-kidney-cancer.html Wed, 01 Jul 2026 11:00:16 EDT news702048243 The prostate is the single organ most frequently afflicted by cancer in men. Prostate cancer affects approximately 4 million American men, with another 330,000 men expected to be diagnosed with the condition this year alone. https://medicalxpress.com/news/2026-07-dna-methylation-patterns-prostate-cancers.html Wed, 01 Jul 2026 07:40:02 EDT news702101821 For patients with benign prostatic hyperplasia (BPH), early functional outcomes are comparable with high-peak-power pulsed Thulium:YAG laser enucleation (p-ThuLEP) and open simple prostatectomy (OSP), but shorter hospitalization and lower transfusion rates are seen with p-ThuLEP, according to a study published online May 30 in Translational Andrology and Urology. https://medicalxpress.com/news/2026-06-early-benign-prostatic-hyperplasia-outcomes.html Tue, 30 Jun 2026 19:20:01 EDT news702053743 New research suggests that low handgrip strength alone is not a reliable predictor of increased prostate cancer risk among older men. The relationship between low handgrip strength (HGS) and prostate cancer has long remained uncertain in the scientific literature. When clinicians consider grip strength as a possible indicator, they are often extrapolating from broader cancer research rather than relying on direct evidence. https://medicalxpress.com/news/2026-06-strength-independent-predictor-prostate-cancer.html Mon, 29 Jun 2026 11:00:03 EDT news701945995 Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, published in the Journal of Experimental Medicine (JEM), demonstrates that direct delivery of these CAR T cells via a catheter can control bladder tumors in mice, raising hopes that a similar approach may be effective in humans. https://medicalxpress.com/news/2026-06-intravesical-car-therapy-door-bladder.html Fri, 26 Jun 2026 10:00:06 EDT news701596381 When high-profile figures publicly discuss their prostate cancer, the public health impact can be immediate. The media coverage raises awareness. More men may seek information or medical advice. https://medicalxpress.com/news/2026-06-celebrities-prostate-cancer.html Fri, 26 Jun 2026 08:40:01 EDT news701673841 There is a significant association between hepatitis C virus (HCV) and overactive bladder (OAB), according to a study published online May 29 in BMC Urology. https://medicalxpress.com/news/2026-06-significant-association-hepatitis-overactive-bladder.html Thu, 25 Jun 2026 16:20:01 EDT news701612791 Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm. The new method enables a detailed analysis even with small samples and allows the detection of the largest number of potential biomarkers identified to date; this advance could help diagnose male infertility and develop future clinical solutions. The paper is published in the journal Cells. https://medicalxpress.com/news/2026-06-methodology-biomarkers-male-infertility.html Thu, 25 Jun 2026 11:20:01 EDT news701603238 The burning pain associated with cystitis affects millions of people around the world, and it can take days or even years for some patients to find relief from bladder pain, infection-related symptoms and the constant need to urinate. A new study led by Flinders University published in Autonomic Neuroscience, has shown how certain pain receptors in the bladder could be targeted to reduce the debilitating effects of this common condition. https://medicalxpress.com/news/2026-06-cannabinoid-receptors-bladder-sensory-pathways.html Thu, 25 Jun 2026 09:20:07 EDT news701594041 The first-in-human fully vascularized bladder graft transplanted with a kidney has reached a promising six-month milestone, according to a new feasibility study published in The Lancet. The procedure, performed in May 2025, demonstrated technical feasibility and early functional success at six months after surgery. https://medicalxpress.com/news/2026-06-month-results-feasibility-early-success.html Wed, 24 Jun 2026 09:20:08 EDT news701511022 The U.S. Food and Drug Administration has approved GSK's Utebzi (tebipenem pivoxil), an oral antibiotic, for the treatment of complicated urinary tract infections (cUTIs). https://medicalxpress.com/news/2026-06-fda-oral-utebzi-antibiotic-complicated.html Tue, 23 Jun 2026 20:40:03 EDT news701418988 The U.S. Food and Drug Administration (FDA) is asking drugmakers to update the prescribing information on testosterone replacement therapy products to reflect newer clinical evidence. https://medicalxpress.com/news/2026-06-testosterone-therapy-limits-fda.html Tue, 23 Jun 2026 18:00:01 EDT news701447607 A new blood test may make it easier to detect the most dangerous forms of prostate cancer early. In a study from Karolinska Institutet, the Stockholm3 blood test detected more clinically significant cancer cases than the PSA test, without subjecting more men to unnecessary testing. The study is published in the Annals of Internal Medicine. https://medicalxpress.com/news/2026-06-blood-high-prostate-cancer-cases.html Tue, 23 Jun 2026 12:00:01 EDT news701432549 The U.S. Food and Drug Administration has approved Merck's Welireg (belzutifan) in combination with pembrolizumab or pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex) for the adjuvant treatment of renal cell carcinoma in adults with a clear cell component at intermediate-high or high risk for recurrence following nephrectomy, or following nephrectomy and resection of metastatic lesions. https://medicalxpress.com/news/2026-06-fda-welireg-pembrolizumab-renal-cell.html Fri, 19 Jun 2026 18:20:01 EDT news701074857 UK media celebrity Jeremy Clarkson this week revealed he has been diagnosed with an aggressive form of prostate cancer. https://medicalxpress.com/news/2026-06-jeremy-clarkson-aggressive-prostate-cancer.html Thu, 18 Jun 2026 23:20:02 EDT news701010690 Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic vulnerabilities are organized within tumors. The study, published in Cancer Discovery, provides a new framework for understanding why patients with bladder cancer may respond differently to treatment. https://medicalxpress.com/news/2026-06-spatial-bladder-cancer-reveals-hidden.html Thu, 18 Jun 2026 15:20:06 EDT news701010795 Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression. https://medicalxpress.com/news/2026-06-hidden-pim1-pathway-prostate-cancer.html Tue, 16 Jun 2026 15:20:03 EDT news700838188 Many medicines begin life with one purpose and end up proving useful for a completely different reason. https://medicalxpress.com/news/2026-06-men-health-drugs-purpose.html Tue, 16 Jun 2026 11:40:03 EDT news700824782 Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing antitumor immunity, according to a preclinical study led by investigators at Weill Cornell Medicine and the Cornell Duffield College of Engineering. https://medicalxpress.com/news/2026-06-experimental-treatment-prostate-tumor-cells.html Mon, 15 Jun 2026 10:00:10 EDT news700735501 GLP-1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago. In fact, the research team found GLP-1s may improve testosterone levels and sperm quality in men with obesity-related low testosterone, while also addressing the underlying effects of obesity. https://medicalxpress.com/news/2026-06-clinical-trials-glp-1s-fertility.html Mon, 15 Jun 2026 10:00:02 EDT news700482361 The U.S. Food and Drug Administration (FDA) has approved pembrolizumab, an immunotherapy, plus belzutifan, a HIF-2α inhibitor, as adjuvant treatment for adult patients with renal cell carcinoma with a clear cell component (ccRCC) at intermediate-high or high risk of recurrence following nephrectomy, with or without resection of metastatic lesions. https://medicalxpress.com/news/2026-06-fda-combination-therapy-higher-cell.html Mon, 15 Jun 2026 07:40:01 EDT news700717921 A research team at Kanazawa University, led by Professor Atsushi Mizokami, Associate Professor Koji Izumi and Specially Appointed Assistant Professor Taiki Kamishima (a fourth-year doctoral student at the Graduate School of Medical Sciences), has elucidated a novel molecular mechanism driving the progression of "double-negative castration-resistant prostate cancer (DNPC)"—one of the most treatment-resistant forms of prostate cancer. https://medicalxpress.com/news/2026-06-hard-prostate-cancer-stroma-kras.html Fri, 12 Jun 2026 08:20:02 EDT news700464441 A Northwestern Medicine study has offered new clues as to why immunotherapy works well for some bladder cancer patients but fails for others, according to a study published in the Journal of Clinical Investigation. https://medicalxpress.com/news/2026-06-immune-biomarkers-response-bladder-cancer.html Wed, 10 Jun 2026 13:40:04 EDT news700313521 Physician-scientists at Kanazawa University have demonstrated, for the first time, the clinical efficacy of chemoimmunotherapy in patients with ultra-rare urachal cancer. Furthermore, their reverse translational research elucidated the mechanism by which the addition of immunotherapy enhances the efficacy of chemotherapy. https://medicalxpress.com/news/2026-06-clinical-efficacy-chemoimmunotherapy-ultra-rare.html Wed, 10 Jun 2026 11:40:02 EDT news700306698 A new UCL-led international trial will assess whether AI can perform as well as expert radiologists at detecting prostate cancer on MRI scans. https://medicalxpress.com/news/2026-06-trial-ai-prostate-mri-cancer.html Mon, 08 Jun 2026 11:20:07 EDT news700135459 Prostate cancer screening is one of the most common decisions men face in primary care, yet many patients make that choice without fully understanding the potential benefits and harms. A new editorial by UNC physician experts argues that shared decision-making should no longer depend on individual clinician effort but instead be built into health care systems. https://medicalxpress.com/news/2026-06-physician-experts-based-approach-prostate.html Thu, 04 Jun 2026 12:40:04 EDT news699793561 The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. Results from a study in the Journal of Internal Medicine suggest that this may prompt a clinician to run tests to uncover an asymptomatic bladder tumor. https://medicalxpress.com/news/2026-06-aspirin-unmask-silent-bladder-cancer.html Wed, 03 Jun 2026 03:10:01 EDT news699611881 Results of a multicenter clinical trial found that adding the investigational adenoviral-based viral immunotherapy aglatimagene besadenovec (alglatimagene, CAN-2409) to standard radiation therapy improved disease-free survival for patients with intermediate- or high-risk localized prostate cancer. The study was led by researchers at the Johns Hopkins University School of Medicine, Johns Hopkins Kimmel Cancer Center, Department of Radiation Oncology and Molecular Radiation Sciences, and Brady Urological Institute. Findings from the study were published June 1 in The Lancet Oncology. https://medicalxpress.com/news/2026-06-immunotherapy-added-therapy-boosts-survival.html Tue, 02 Jun 2026 16:40:05 EDT news699629521 The Society of Interventional Radiology (SIR) has published new practice guidance for the use of prostatic artery embolization (PAE) to treat enlarged prostate (also called benign prostatic hyperplasia or BPH). The guidance appears in the Journal of Vascular and Interventional Radiology to coincide with the start of Men's Health Month in June. https://medicalxpress.com/news/2026-06-guidance-treatment-enlarged-prostate.html Tue, 02 Jun 2026 15:30:01 EDT news699631562