https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology Men with severely reduced fertility are at greater risk of developing other health conditions later in life. A research team from Lund University in Sweden has now shown that these men are also more likely to develop colorectal cancer and thyroid cancer. https://medicalxpress.com/news/2026-04-severe-male-infertility-higher-colorectal.html Thu, 16 Apr 2026 14:20:06 EDT news695561041 Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated. In a new study published in Nature Communications, investigators found that EZH2—a protein long recognized for its role in modifying DNA-packaging histones—also plays a direct and previously unknown role in RNA editing in prostate cancer. https://medicalxpress.com/news/2026-04-major-cancer-protein-hijacks-rna.html Wed, 15 Apr 2026 17:20:05 EDT news695487721 A recent randomized clinical trial has found that men with localized, intermediate-risk prostate cancer recovered faster and experienced less short-term impact on their daily lives when treated with MRI-guided, transurethral ultrasound ablation (TULSA) compared with robotic prostate surgery. The results of the CAPTAIN Trial were presented at the SIR 2026 Annual Scientific Meeting in Toronto. The work is published in the Journal of Vascular and Interventional Radiology. https://medicalxpress.com/news/2026-04-faster-recovery-minimally-invasive-prostate.html Mon, 13 Apr 2026 21:40:01 EDT news695315039 More than 35,000 men in the United States die from prostate cancer each year. Now, a new study reveals the immune cell weaponry we might use to save lives. https://medicalxpress.com/news/2026-04-prostate-immune-niches-cells-persist.html Sat, 11 Apr 2026 10:00:01 EDT news694774170 Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its potential as a therapeutic target, according to a recent study published in Nature Communications. Rendong Yang, Ph.D., associate professor of Urology and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, was co-corresponding author of the study. https://medicalxpress.com/news/2026-04-coding-rna-therapeutic-cancer.html Thu, 09 Apr 2026 16:00:04 EDT news694965789 Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder cancer (NMIBC), in which the tumors are confined to the inner layers of the bladder. Despite early detection, the disease frequently returns. https://medicalxpress.com/news/2026-04-urine-bladder-cancer.html Wed, 08 Apr 2026 12:20:06 EDT news694867082 Women's HRT patches can treat prostate cancer just as effectively as standard hormone injections—but with fewer of the worst side effects—according to a large UK trial published in the New England Journal of Medicine. The finding could change how men with prostate cancer that has spread beyond the gland are treated for years to come. https://medicalxpress.com/news/2026-04-hrt-patches-prostate-cancer.html Tue, 07 Apr 2026 20:30:01 EDT news694776445 Cornell scientists have taken a major step toward developing a safe, reversible, long-acting and 100% effective nonhormonal male contraceptive, considered the holy grail of male contraception. A proof-of-principle study in mice, six years in the making, shows how targeting a natural checkpoint in meiosis, the process by which sex cells reproduce, safely stopped sperm production. The study is published in the journal Proceedings of the National Academy of Sciences. https://medicalxpress.com/news/2026-04-big-safe-reversible-male-contraception.html Tue, 07 Apr 2026 16:20:03 EDT news694791661 New findings from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM), published in Pharmacological Research, show that an innovative drug effectively prevents prostate tumors from spreading to an advanced and incurable stage in the bones. The targeted small molecule inhibitor, IVMT-Rx-4, also enhances standard-of-care chemotherapy treatment for the disease, offering significant potential for a paradigm shift in the treatment of metastatic tumors. https://medicalxpress.com/news/2026-04-therapy-halts-prostate-cancer-bone.html Thu, 02 Apr 2026 19:00:02 EDT news694365242 Among middle-aged and older men, a higher percentage of total food weight from ultraprocessed food (UPF) is associated with a higher risk for incident benign prostatic hyperplasia (BPH), according to a study published online March 14 in the Nutrition Journal. https://medicalxpress.com/news/2026-03-benign-prostatic-hyperplasia-higher-percentage.html Tue, 31 Mar 2026 14:40:02 EDT news694183046 Where previous research showed that PSMA therapy for prostate cancer can prolong the lives of patients who have exhausted all other treatment options, a new study now demonstrates that the therapy is also effective in an earlier stage of the disease. As a result, more burdensome hormone therapy can be postponed by twenty additional months, shows research led by Radboudumc. https://medicalxpress.com/news/2026-03-psma-therapy-delays-hormone-prostate.html Tue, 31 Mar 2026 12:20:05 EDT news694174321 Patients with urinary tract infections (UTIs) could receive the right antibiotic far sooner, thanks to a new test that produces results within hours rather than days. Researchers at the University of Reading, working with colleagues at the University of Southampton and Hampshire Hospitals NHS Foundation Trust, have shown that a novel method testing directly from urine can tell doctors which antibiotic will work in an average of 5.85 hours. Standard laboratory testing currently takes two to three days. https://medicalxpress.com/news/2026-03-rapid-urine-effective-uti-antibiotics.html Mon, 30 Mar 2026 19:00:01 EDT news694079234 The U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer. https://medicalxpress.com/news/2026-03-fda-biotech-firm-cancer-drug.html Sun, 29 Mar 2026 10:00:14 EDT news693753225 For adults aged 20 to 69 years, overactive bladder (OAB) is associated with an increased risk for a recent fall, according to a study published online March 19 in Neurourology and Urodynamics. https://medicalxpress.com/news/2026-03-overactive-bladder-independently-linked-fall.html Fri, 27 Mar 2026 04:08:42 EDT news693803265 Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers. Men with cancer that has spread just outside the prostate are given hormone therapy to suppress levels of testosterone which the cancer needs to grow. Most commonly, this is done by injections of drugs that block testosterone production. https://medicalxpress.com/news/2026-03-clinical-trial-hormone-patches-effective.html Wed, 25 Mar 2026 17:00:03 EDT news693656101 When it comes to reproduction, female biology is often described in terms of a ticking clock. Women are born with most of their lifetime supply of eggs, meaning that a woman's age is usually the same as the age of her eggs. Older women therefore produce older eggs. https://medicalxpress.com/news/2026-03-ejaculating-boost-sperm-motility-dna.html Wed, 25 Mar 2026 15:10:01 EDT news693654996 Prostate cancer affects one in five Australian men, making it the most common cancer in the country. Now, researchers at the Garvan Institute of Medical Research have produced the world's most detailed cellular "atlas" of early-stage prostate cancer, revealing the earliest changes that lead to the disease. https://medicalxpress.com/news/2026-03-cellular-atlas-prostate-cancer-avenues.html Wed, 25 Mar 2026 10:00:12 EDT news693651361 Researchers at Texas A&M Health have identified a molecular mechanism that increases cholesterol levels inside prostate cancer cells—an important process that may help explain how some tumors progress and become resistant to treatment. https://medicalxpress.com/news/2026-03-fgfr1-boosts-cholesterol-uptake-prostate.html Sat, 21 Mar 2026 07:20:01 EDT news693281143 As a urological surgeon, I meet many patients with chronic (long-term) kidney disease. Sometimes, I see patients that have progressed to the point where their kidneys do not work at all. This leads to the toxic build-up of waste products, meaning they need regular dialysis or a kidney transplant. https://medicalxpress.com/news/2026-03-im-kidney-surgeon.html Fri, 20 Mar 2026 20:30:01 EDT news693213170 Kidney stones can cause some of the most intense pain people ever experience, affecting daily life and leading many to hospital emergency visits. It affects one in 11 people in the U.S., and almost half will experience a recurrence. A major new study from the Urinary Stone Disease Research Network, coordinated by the Duke Clinical Research Institute, tested whether a behavioral program could help people drink enough fluids to prevent stones from coming back. https://medicalxpress.com/news/2026-03-largest-kind-hydration-strategy-kidney.html Thu, 19 Mar 2026 19:30:01 EDT news693131101 Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. Their findings, published in Cancer Discovery, show that common signs of inflammation in the blood are linked to immune cells inside tumors that block the body's ability to fight cancer. https://medicalxpress.com/news/2026-03-inflammatory-immune-pathway-immunotherapy-resistance.html Wed, 18 Mar 2026 11:40:06 EDT news693052381 Use of virtual reality (VR) to explain shock wave lithotripsy (SWL) can help improve calmness and satisfaction among patients, according to a study presented at the European Association of Urology Congress, held from March 13 to 16 in London. https://medicalxpress.com/news/2026-03-eau-patient-satisfaction-virtual-reality.html Mon, 16 Mar 2026 22:50:01 EDT news692889309 One in ten emergency patients with visible blood in their urine dies within three months of presenting at hospital emergency departments, new research has found. The WASHOUT study, presented at the European Association of Urology Congress (EAU26) in London, has found that a scan within 48 hours could reduce this risk. https://medicalxpress.com/news/2026-03-scan-emergency-department-patients-blood.html Sun, 15 Mar 2026 20:10:01 EDT news692551321 Prostate cancer screening compares favorably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research. The findings are presented at the European Association of Urology Congress (EAU26) in London. The research has also been accepted for publication in European Urology. https://medicalxpress.com/news/2026-03-prostate-cancer-screening-good-breast.html Sat, 14 Mar 2026 20:10:01 EDT news692551501 A smartphone app designed to tackle the underlying psychological causes of premature ejaculation can significantly improve sex life and delay ejaculation, while offering a way to reduce stigma around the condition, say researchers. Data from the CLIMACS study are presented at the European Association of Urology Annual Congress (EAU26) in London. It is the first study to test a digital-first approach for treating premature ejaculation at home. https://medicalxpress.com/news/2026-03-smartphone-app-men-longer-bed.html Fri, 13 Mar 2026 20:10:01 EDT news692551681 An interdisciplinary team from the University Hospitals Cologne and Bonn have conducted the first prospective study to investigate whether very early intervention in unborn children with congenital lower urinary tract obstruction (cLUTO) can improve their chances of survival and subsequent kidney function. The researchers aim to fundamentally improve the prognosis for this serious disease and ideally spare affected children from dialysis. https://medicalxpress.com/news/2026-03-early-intervention-severe-fetal-megacystis.html Fri, 13 Mar 2026 16:00:03 EDT news692627950 Using virtual reality (VR) to explain what to expect ahead of a medical procedure could help patients better understand their treatment and reduce anxiety, a new study suggests. The research was presented at the European Association of Urology Congress in London (EAU26). https://medicalxpress.com/news/2026-03-vr-anxiety-people-medical-procedures.html Thu, 12 Mar 2026 20:10:01 EDT news692525101 An imaging test could safely halve the number of people who need a biopsy for suspected prostate cancer following inconclusive or reassuring results from an MRI scan, new research has found. Findings from the PRIMARY2 trial have been presented at the European Association of Urology Congress in London (EAU26). https://medicalxpress.com/news/2026-03-scan-prostate-cancer-cells-biopsies.html Thu, 12 Mar 2026 20:00:01 EDT news692523293 Prostate cancer is one of the leading causes of cancer-related death in men, and some experts project the number of cases to rise over the coming decades. But in a recent Urologic Oncology article, Yale School of Medicine (YSM) researchers say they are hopeful that advancements in technology for the detection and treatment of prostate cancer will actually reduce mortality rates. https://medicalxpress.com/news/2026-03-prostate-cancer-deaths-decrease.html Thu, 12 Mar 2026 17:30:02 EDT news692528255 A new study led by researchers at The University of Texas MD Anderson Cancer Center found that prostate cancer patients with low testosterone levels may have a higher risk of cancer progressing to a more aggressive form while under active surveillance. The findings, published in the Journal of Urology, suggest that baseline testosterone may serve as a useful clinical marker to better stratify risk and tailor monitoring strategies for patients choosing active surveillance. https://medicalxpress.com/news/2026-03-testosterone-prostate-cancer-surveillance.html Tue, 10 Mar 2026 20:10:05 EDT news692362728