https://medicalxpress.com/urology-news/ en-us Latest medical news and research in Urology Better cardiovascular health (CVH) is nonlinearly and inversely associated with overactive bladder (OAB), according to a study published in the August issue of the Annals of Medicine & Surgery. https://medicalxpress.com/news/2026-09-cardiovascular-health-inversely-linked-overactive.html Thu, 17 Sep 2026 17:40:09 EDT news708868188 A new study published in Nature has established the foundational landscape of tumor evolution in bladder cancer and differences among cancer subtypes, which could point toward better diagnosis and treatment of the disease. https://medicalxpress.com/news/2026-09-earliest-bladder-cancer-metastasis-seed.html Wed, 16 Sep 2026 16:40:07 EDT news708791041 An updated, evidence-based guideline has been developed for the diagnosis and management of childhood nocturnal enuresis (NE). The guideline was published online July 10 in the World Journal of Pediatrics. https://medicalxpress.com/news/2026-09-guideline-diagnosis-childhood-nocturnal-enuresis.html Wed, 16 Sep 2026 15:40:02 EDT news708786015 For appropriately selected patients with muscle-invasive bladder cancer, preserving the bladder can be a curative treatment option rather than removing it, according to a new clinical guideline from the American Society for Radiation Oncology (ASTRO). The recommendations support trimodal therapy as an alternative to bladder removal and provide guidance on the use of radiation therapy after surgery and for patients with metastatic or symptomatic disease. The guideline, ASTRO's first to focus specifically on radiation therapy across bladder cancer care, was published in Practical Radiation Oncology, ASTRO's clinical practice journal. https://medicalxpress.com/news/2026-09-clinical-guideline-therapy-bladder-cancer.html Wed, 16 Sep 2026 10:20:07 EDT news708768662 An elevated PSA level in the blood may indicate prostate cancer but does not allow for a definitive diagnosis. Where there is a corresponding suspicion, a tissue sample is usually taken from the prostate. A study by the Medical University of Vienna now shows that a specialized form of imaging—known as PSMA-PET/CT—could provide important additional information even before such a biopsy is carried out. https://medicalxpress.com/news/2026-09-prostate-cancer-specialized-imaging-unnecessary.html Tue, 15 Sep 2026 17:40:07 EDT news708704822 Combining the targeted therapy olaparib with an additional immunotherapy may improve immune response in a subgroup of patients with metastatic castration-resistant prostate cancer who responded poorly to initial treatment, according to a Northwestern Medicine study published in The Journal of Clinical Investigation. https://medicalxpress.com/news/2026-09-combination-therapy-immune-response-advanced.html Thu, 10 Sep 2026 15:00:01 EDT news708262756 Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with it for years while it progresses aggressively in others. https://medicalxpress.com/news/2026-09-dna-signatures-reveal-prostate-cancers.html Wed, 09 Sep 2026 11:00:20 EDT news708169081 New research in the International Journal of Clinical Practice suggests that workplace psychological stress may impair erectile function in young men by affecting certain stress-management pathways in the brain and reducing testosterone levels. https://medicalxpress.com/news/2026-09-stress-erectile-dysfunction-young-men.html Wed, 09 Sep 2026 03:10:02 EDT news708087121 Findings from STAMINA, the largest trial of its kind, published in The Lancet Oncology, show that a purpose-designed lifestyle program offering structured exercise, dietary advice and behavioral support as part of routine cancer care reduced deterioration in quality of life in men undergoing treatment for prostate cancer by up to one-third. https://medicalxpress.com/news/2026-09-trial-prostate-cancer-treatment-side.html Mon, 07 Sep 2026 10:00:04 EDT news707993123 Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects. Now, scientists have identified an unexpected participant in androgen chemistry: a bacterium from the human urinary tract that can convert the steroid precursor DHEA into testosterone under laboratory conditions. https://medicalxpress.com/news/2026-09-bacteria-testosterone-prostate-cancer.html Mon, 07 Sep 2026 09:00:04 EDT news707989741 For patients with nonmetastatic prostate cancer, focal therapy use has remained uncommon across risk groups, and its use was defined as inappropriate in about half of recipients, according to a research letter published online Aug. 13 in the JAMA. https://medicalxpress.com/news/2026-09-focal-therapy-uncommon-nonmetastatic-prostate.html Sun, 06 Sep 2026 12:00:01 EDT news707657608 A lab-grown micro bladder may explain why urinary tract infections (UTIs) return so frequently, according to a study led by researchers at UCL, the University of Oxford and the University of Leicester. https://medicalxpress.com/news/2026-09-micro-bladder-clues-recurrent-utis.html Fri, 04 Sep 2026 05:00:01 EDT news707653211 New research has found that more than 9 in 10 patients with bladder cancer were identified through a noninvasive urine test after urgent referral. The study, led by the University of Birmingham and Nonacus Ltd., involved 964 patients across seven NHS urology departments to examine the real-world significance of testing for bladder cancer using a commercially available urine test. GALEAS™ Bladder, which tests genomic information from a patient's urine for traces of bladder cancer, detected 71 of 77 cancers (92.2%) among the nearly 1,000 patients. https://medicalxpress.com/news/2026-09-urine-ten-bladder-cancers-clinical.html Wed, 02 Sep 2026 10:00:09 EDT news707557312 There is a negative link between estimated glucose disposal rate (eGDR) and benign prostatic hyperplasia (BPH) in men, according to a study published online Aug. 25 in The Aging Male. https://medicalxpress.com/news/2026-08-glucose-disposal-inversely-linked-benign.html Mon, 31 Aug 2026 16:30:08 EDT news707399969 A newly developed radiotheranostic pair, 68Ga/177Lu-NYM096, can identify tumors and effectively deliver targeted radiotherapy to patients with metastatic clear cell renal cell carcinoma (ccRCC). Using a small-molecule compound, the new approach helps mitigate toxicity issues common with treatment, offering a safe and feasible strategy for those with end-stage disease. This research was published in the September issue of The Journal of Nuclear Medicine. https://medicalxpress.com/news/2026-08-generation-theranostic-pair-strategy-metastatic.html Sat, 29 Aug 2026 18:30:01 EDT news707137676 Allograft survival is unaffected when kidney transplant (KT) is performed after a short-term pretransplant dialysis duration (PTDD), according to a study published online Aug. 24 in the International Journal of Urology. https://medicalxpress.com/news/2026-08-short-term-pretransplant-dialysis-affect.html Fri, 28 Aug 2026 12:40:04 EDT news707137601 A novel prognostic stratification model can predict indwelling catheter conversion (ICC) among patients with early-stage spinal cord injury (SCI) and neurogenic bladder (NB), according to a study published online Aug. 23 in Neurourology and Urodynamics. https://medicalxpress.com/news/2026-08-ai-indwelling-catheter-conversion-early.html Thu, 27 Aug 2026 14:40:01 EDT news707055481 Researchers investigating the role of progranulin in cancer progression have previously identified the signaling receptor EphA2 as critical in tumor establishment and a potential target to enhance the effectiveness of chemotherapy. While the exact molecular mechanisms of action are still not well understood, the growth factor progranulin is known to be involved in several human pathologies, including frontotemporal dementia (FTD), immune response and cancer. A new study identifies the protein FAM120A as a critical effector in the progranulin/EphA2 tumorigenic axis. https://medicalxpress.com/news/2026-08-precision-medicine-influential-protein-bladder.html Wed, 26 Aug 2026 17:20:03 EDT news706974902 Men are likely to suffer more extensive heart attacks than women. Studies have shown that male sex hormones, such as testosterone, intensify inflammation during an acute heart attack and lead to a larger area of damage. According to a study from the University of Gothenburg, patients treated with medication for benign prostatic hyperplasia at the time of a severe acute heart attack experienced fewer serious complications from the attack. https://medicalxpress.com/news/2026-08-prostate-medication-linked-complications-heart.html Wed, 26 Aug 2026 10:00:03 EDT news706954621 Results of the NRG Oncology NRG-GU005 clinical study comparing stereotactic body radiation therapy (SBRT) with moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) for patients with localized intermediate-risk prostate cancer indicate that SBRT improved bowel health-related quality of life (HRQOL) in this patient population. There was no significant improvement with SBRT in the other primary objectives, including urinary HRQOL and disease-free survival. These results are now published in the JAMA following their presentation during the Plenary Session of the 2025 American Society for Radiation Oncology Annual Meeting in San Francisco. https://medicalxpress.com/news/2026-08-session-prostate-bowel-quality-life.html Tue, 25 Aug 2026 14:40:03 EDT news706882681 Bladder cancer claims 220,000 lives globally each year, with symptoms sometimes mistaken for other conditions such as kidney stones. Now researchers have developed an artificial intelligence system that can identify bladder cancer patients up to five years before their official diagnosis, potentially revolutionizing screening for the disease. https://medicalxpress.com/news/2026-08-bladder-cancer-years-diagnosis-ai.html Tue, 25 Aug 2026 10:40:05 EDT news706868999 About 1 in 8 men are diagnosed with prostate cancer during their lifetime. Although many survive, it can develop into metastatic disease. https://medicalxpress.com/news/2026-08-drug-combination-advanced-prostate-cancer.html Fri, 21 Aug 2026 12:00:03 EDT news706528627 A machine learning model can predict overactive bladder (OAB) risk in women using common reproductive and sociodemographic data, according to a study published online Aug. 12 in JMIR Medical Informatics. https://medicalxpress.com/news/2026-08-women-overactive-bladder.html Thu, 20 Aug 2026 14:40:02 EDT news706454580 Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators. https://medicalxpress.com/news/2026-08-prostate-cancer-hijacks-amino-acid.html Thu, 20 Aug 2026 11:00:12 EDT news706368901 A urinary tract infection that follows a moderate brain injury can worsen cognitive problems caused by the injury, new research in mice shows. https://medicalxpress.com/news/2026-08-bladder-infection-brain-injury-worsens.html Wed, 19 Aug 2026 17:20:04 EDT news706376342 The internet's obsession with "maxxing" has turned almost every aspect of self-improvement into a trend. https://medicalxpress.com/news/2026-08-saunas-ice-affect-male-fertility.html Sat, 15 Aug 2026 08:40:03 EDT news705906791 As focal therapy gains popularity as a less invasive treatment option for some men with prostate cancer, a national study led by researchers at the University of Pittsburgh found that some men may be receiving treatment that is either unnecessary or not aggressive enough for their cancer. https://medicalxpress.com/news/2026-08-prostate-cancer-focal-therapy-fall.html Thu, 13 Aug 2026 11:00:07 EDT news705671341 Three decades after UC San Francisco pioneered "active surveillance" for patients with low-risk prostate cancer, a new study has found that the vast majority of veterans with the diagnosis pursued this option instead of treatment. https://medicalxpress.com/news/2026-08-early-prostate-cancer-surveillance-choice.html Thu, 13 Aug 2026 11:00:04 EDT news705833174 Researchers at Moffitt Cancer Center have developed three mathematical biomarkers that may help physicians personalize adaptive therapy for prostate cancer by predicting treatment outcomes early in treatment. The biomarkers are specialized mathematical measures calculated from routine prostate-specific antigen (PSA) blood tests. https://medicalxpress.com/news/2026-08-mathematical-personalize-therapy-prostate-cancer.html Thu, 13 Aug 2026 08:20:01 EDT news705821247 A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer—such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles—after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation. https://medicalxpress.com/news/2026-08-traditional-prostate-cancer-factors-hormone.html Mon, 10 Aug 2026 17:20:06 EDT news705600421