SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...
Dec 23, 2020
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Researchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome
Sep 09, 2020
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A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.
May 06, 2019
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A researcher at the UPV/EHU participated in a study describing the loss of dynamics and subsequent impairment of the dendritic spines in Alzheimer's disease. Dendritic spines are the compartments of neurons responsible for ...
Jan 18, 2019
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Cancer cells have evolved multiple escape strategies to circumvent the body's immune defenses, such as the attack by natural killer (NK) cells that normally kill abnormal cells by releasing cytotoxic products. While studying ...
Oct 24, 2018
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Breast cancer is one of the most common cancers in the United States, striking 1 out of 8 women. About 80 percent of all breast cancers are estrogen receptor-positive, in which cancer growth is fueled by estrogen.
Sep 11, 2018
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Ashleigh Schaffer, Ph.D., assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process ...
Aug 09, 2018
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In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles. It is also true on a cellular level: The cytoskeleton, composed of ...
Jul 26, 2018
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More than 50 billion cells die in the human body every day, a spectacle of programmed cell death called apoptosis. These cells undergo internal degradation and then fracture into apoptotic bodies that are scavenged by immune ...
Jun 23, 2015
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Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of ...
Feb 12, 2015
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