Medical research

Changing the perspective on the 'Cinderella of the cytoskeleton'

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...

Oncology & Cancer

Form drives function in cancer proliferation

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

Alzheimer's disease & dementia

Neuronal cytoskeletons involved in Alzheimer's disease

A researcher at the UPV/EHU participated in a study describing the loss of dynamics and subsequent impairment of the dendritic spines in Alzheimer's disease. Dendritic spines are the compartments of neurons responsible for ...

Immunology

Faulty cytoskeleton impairs immune cells

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles. It is also true on a cellular level: The cytoskeleton, composed of ...

Immunology

Cells too stiff to scavenge leads to lupus, an autoimmune disease

More than 50 billion cells die in the human body every day, a spectacle of programmed cell death called apoptosis. These cells undergo internal degradation and then fracture into apoptotic bodies that are scavenged by immune ...

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