Oncology & Cancer

Secret vulnerabilities of cancer's 'Death Star' protein revealed

Researchers at the Center for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are ...

Medications

Antibiotics for acne: Study shows why one works best

A new study brings precision to the understanding of which antibiotics work best for acne treatment and why. This is important for two key reasons. Acne affects nearly everyone at some point in life—it is, in fact, the ...

Oncology & Cancer

Indirectly influencing cancer's out-of-control cell replication

As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...

HIV & AIDS

Unique HIV reservoirs in elite controllers

Xu Yu, MD, Ragon group leader, recently published a study entitled "Distinct viral reservoirs in individuals with spontaneous control of HIV-1," in Nature. Yu's lab, in collaboration with Ragon group leaders Mathias Lichterfeld, ...

Alzheimer's disease & dementia

Novel compound is promising drug candidate for Alzheimer's disease

A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer's disease. As published ...

Medications

New research will guide development of new anti-influenza drugs

By analyzing the molecular details of how artificially created drug-resistant flu strains manage to survive treatment, St. Jude Children's Research Hospital scientists have developed insights to guide development of powerful ...

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