Diseases, Conditions, Syndromes

Dynamics of adaptive immunity in tuberculosis uncovered

Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as slowly. Until recently, the dynamic interplay between bacteria and the host's immune ...

Medical research

A hybrid vehicle that delivers DNA

A new hybrid vehicle is under development. Its performance isn't measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza ...

Medical research

Vaccine adjuvant uses host DNA to boost pathogen recognition

Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. In the March 19, 2013, issue of the Proceedings ...

Health

PFAS can suppress white blood cell's ability to destroy invaders

In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst—the method white blood cells known as neutrophils use to kill invading pathogens. The study is an important first ...

Medical research

Ebola's secret weapon revealed

Researchers have discovered the mechanism behind one of the Ebola virus' most dangerous attributes: its ability to disarm the adaptive immune system.

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