Oncology & Cancer

Growth factor R-spondin suppresses colorectal tumor growth

Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...

Oncology & Cancer

Cancer mutations caused by bacterial toxin preventable

Reports show that cancer is the second leading cause of death globally. Scientists from Duke-NUS Medical School have found DNA mutations in some cancers that link them to a bacterial toxin called colibactin. Their findings, ...

Psychology & Psychiatry

Study links APC gene to learning and autistic-like disabilities

Autistic-like behaviors and decreased cognitive ability may be associated with disruption of the function of the Adenomatous Polyposis Coli (APC) gene. When Tufts researchers deleted the gene from select neurons in the developing ...

Oncology & Cancer

Finding a tumor suppressor's groove

The tumor suppressor protein called adenomatous polyposis coli (APC) is a central genetic risk factor for colorectal cancer. In fact, mutations that potentially alter the structure or function of this protein are found in ...

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