Diseases, Conditions, Syndromes

Scientists discover new mechanism associated with severe COVID-19

Researchers at the University of São Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway. The discovery helps explain at the molecular level ...

Medical research

Multiple sclerosis drug works in a surprising way

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce ...

Biomedical technology

Sensor monitors disease severity by rapidly measuring lactate levels

Scientists have developed a prototype sensor that could help doctors rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples from patients, aiding in the rapid assessment of the severity of some diseases.

Immunology

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...

Medical research

New approach to treating osteoarthritis advances

The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body's millions of cells. The molecule most used to ...

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