Medical research

Functional insulin-producing cells grown in lab

UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes.

Medical research

Scientists have identified a bone marrow backup system

New research from the Stowers Institute for Medical Research has identified the backup for an important biological system—the hematopoietic system, whose adult stem cells constantly replenish the body's blood supply.

Inflammatory disorders

Cells using sugar for metabolic process may fight inflammation

New research by a team from the FAMU-FSU College of Engineering has discovered that a type of adult stem cell found in a variety of tissues can be manipulated to enhance tissue regeneration and potentially treat inflammatory ...

Cancer

FDA approves first-line therapy for peripheral T-cell lymphoma

(HealthDay)—The U.S. Food and Drug Administration on Friday expanded approval for the use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with specific types of peripheral ...

Medical research

Skeletal stem cells regress when tasked with extensive regeneration

Adult mouse skeletal stem cells in the jaw revert to a more developmentally flexible state when called upon to regenerate large portions of bone and tissue, according to a study by researchers at the Stanford University School ...

Cancer

Colorectal cancer: Tipping the scales

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...

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Adult stem cell

Adult stem cells are undifferentiated cells, found throughout the body after embryonic development, that multiply by cell division to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells (from Greek Σωματικóς, meaning of the body), they can be found in juvenile as well as adult animals and humans.

Scientific interest in adult stem cells has centered on their ability to divide or self-renew indefinitely, and generate all the cell types of the organ from which they originate, potentially regenerating the entire organ from a few cells. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not considered to be controversial as they are derived from adult tissue samples rather than destroyed human embryos. They have mainly been studied in humans and model organisms such as mice and rats.

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