Including African Americans in genomic studies can result in five times more accurate prediction of disease risk in the African population, potentially enabling earlier diagnosis and access to treatment
Jun 3, 2022
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Many studies have suggested that the genetics of skin pigmentation are simple. A small number of known genes, it is thought, account for nearly 50 percent of pigment variation. However, these studies rely on datasets consisting ...
Nov 30, 2017
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A consortium led by scientists at the University of Oxford and Harvard Medical School has constructed the world's most detailed genetic map.
Jul 20, 2011
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More than just a tool for predicting health, modern genetics is upending long-held assumptions about who we are. A new study by Harvard researchers casts new light on the intermingling and migration of European, Middle Eastern ...
May 24, 2011
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While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career. As a then-postdoctoral fellow at the Broad Institute of MIT and Harvard, Sabeti ...
Feb 8, 2024
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Researchers from the University of Pennsylvania have discovered key insights into the molecular basis of skin color variations among African populations. Their findings, published in Nature Genetics, broaden the understanding ...
Jan 12, 2024
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An international team of researchers has found a genetic variant that may explain why some people of African ancestry have naturally lower viral loads of HIV, reducing their risk of transmitting the virus and slowing progress ...
Aug 2, 2023
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High tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer patient populations, researchers report on September 29 in the journal Cancer ...
Sep 29, 2022
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Lung cancer is the leading cause of cancer death in the U.S., making up 25% of cancer deaths. With obesity rates simultaneously rising, researchers have investigated the connections between cancer risk and body mass index ...
Sep 12, 2022
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Genome-wide association studies (GWAS) have typically excluded diverse and minority individuals in the search for gene variants that confer risk of disease. Researchers at Massachusetts General Hospital (MGH), the Broad Institute ...
Feb 2, 2021
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