Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers including Mathias Jucker ...
Nov 17, 2020
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There are currently 8 million patients with Parkinson's disease in the world.
May 5, 2023
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Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer's, Parkinson's, and type II diabetes. While the exact role these fibrils play ...
Aug 16, 2019
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586
The older we grow, the weaker our muscles get, riddling old age with frailty and physical disability. But this doesn't only affect the individual, it also creates a significant burden on public healthcare. And yet, research ...
Jan 19, 2021
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In Alzheimer's disease, the degeneration of brain cells is linked to formation of toxic protein aggregates and deposits known as amyloid plaques. Similar processes also play an important role in type 2 diabetes. A research ...
Nov 9, 2022
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Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging. In recent years, studies on different model organisms have already shown ...
Apr 3, 2023
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Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger ...
Feb 9, 2012
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Researchers at Lund University have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease. The research findings are ...
Aug 18, 2011
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Huntington's, Alzheimer's, ALS, and multiple other neurodegenerative diseases share a commonality: They are all characterized by proteins (different ones for each disease) aggregating in neurons within the brain and nervous ...
Feb 16, 2022
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(Medical Xpress)—Rice University scientists have discovered a new way to look inside living cells and see the insoluble fibrillar deposits associated with Parkinson's disease.
Dec 17, 2012
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