Alzheimer's disease & dementia

Using math to help treat Alzheimer's, Parkinson's and other diseases

Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer's, Parkinson's, and type II diabetes. While the exact role these fibrils play ...

Oncology & Cancer

Research shows human cells assembling into fractal-like clusters

Tree-like branching structures are everywhere in the human body, from the bronchial system in the lungs to the spidering capillaries that supply blood to the extremities. Researchers have long worked to understand the cellular ...

Neuroscience

Tissue model reveals role of blood-brain barrier in Alzheimer's

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...

Medical research

Protein shows promise in treating Parkinson's disease

The true cause of Parkinson's disease is still a mystery to researchers, although they do know that in many patients, a protein called alpha-synuclein (aSyn) tends to aggregate in brain cells. But a different protein could ...

Medical research

Breaking down pathological protein aggregates

ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson's and other neurodegenerative diseases. This new finding might ...

Parkinson's & Movement disorders

Novel device opens new doors for Parkinson's disease diagnostics

Currently, there are no disease-modifying therapies for the treatment of Parkinson's disease; however, one potential strategy for treatment is to prevent α-synuclein aggregation. As a first step, researchers at Osaka University ...

Neuroscience

How fish brain cells react to Alzheimer's disease

Zebrafish, in contrast to humans, have outstanding regenerative capacities: If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers ...

Cardiology

Experimental antiplatelet compound for acute stroke shows promise

An experimental antiplatelet compound inhibited clot formation without increasing bleeding, a common and potentially dangerous side effect of current anticlotting therapies, according to new phase I research in Arteriosclerosis, ...

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Aggregation

Aggregation may refer to uses in:

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