A common mutation in a key enzyme involved in alcohol metabolism increases damage in cells from patients with Alzheimer's disease and in mice, according to a study by researchers at the Stanford University School of Medicine.
Dec 11, 2019
0
15408
If your face goes red when drinking alcohol, you're not alone. More than one in three people with East Asian heritage (Chinese, Japanese and Korean) experience facial flushing when drinking beer, wine or spirits.
Dec 28, 2017
0
9
Researchers used gene transfer to block the expression of one of the two main enzymes that break down alcohol in the liver, leading to the accumulation in liver cells of acetaldehyde, a metabolic byproduct of ethanol. The ...
Sep 18, 2017
0
4
People who have reduced enzyme activity to breakdown active aldehyde, i.e., those who become easily inebriated, are more likely to develop fatty liver disease even if they do not drink alcohol. This discovery was made by ...
May 24, 2016
0
31
Pain from inflammation sidelines thousands of Americans each year. Many face a tough choice: deal with the pain, take a potentially addictive opioid or use a nonsteroidal anti-inflammatory drug that may increase risk for ...
Aug 27, 2014
0
1
Researchers know that gender differences exist in the prevalence, characteristics, and course of alcohol dependence (AD). Polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are strong genetic ...
Aug 15, 2011
0
0
Chilean researchers said Thursday they are developing a vaccine against alcoholism that could be tested on humans starting next year and works by neutralizing an enzyme that metabolizes alcohol.
Jan 06, 2011
0
0
Mexican researchers examined the polymorphisms of three enzymes -- alcohol dehydrogenase (ADH1B), aldehyde dehydrogenase (ALDH2) and cytochrome P4502E1 (CYP2E1) -- in the Mestizo and Huichol groups.The Huichols, an indigenous ...
Oct 26, 2009
0
0
Kudzu extracts have been used in Chinese folk medicine to treat alcoholism for about 1,000 years. Daidzin is an anti-drinking substance in kudzu. A synthetic form of daidzin, called CVT-10216, can successfully reduce drinking ...
Aug 11, 2009
4
0
Personality factors can influence the development of alcohol dependence (AD). Researchers examined a group of AD individuals with the inactive form of aldehyde dehydrogenase-2 (ALDH2) - persons who would normally have a ...
Mar 03, 2009
0
0
