Gerontology & Geriatrics

Breaking the vicious cycles of age-related diseases

Biologist Aleksey Belikov from the Moscow Institute of Physics and Technology has proposed that rapid progression of age-related diseases may result from the formation of so-called vicious cycles. An example of this is when ...

Parkinson's & Movement disorders

Defective glial cells can push neurons toward Parkinson's disease

Researchers from the University of Barcelona have shown that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is the hallmark of Parkinson's disease. The studied ...

Parkinson's & Movement disorders

Parkinson's disease experts devise a roadmap

A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the progression of Parkinson's disease (PD). Experts in the ...

Parkinson's & Movement disorders

A toxin that travels from stomach to brain may trigger Parkinsonism

Combining low doses of a toxic herbicide with sugar-binding proteins called lectins may trigger Parkinsonism—symptoms typical of Parkinson's disease like body tremors and slowing of body motions—after the toxin travels ...

Parkinson's & Movement disorders

Road to cell death more clearly identified for Parkinson's disease

In experiments performed in mice, Johns Hopkins researchers report they have identified the cascade of cell death events leading to the physical and intellectual degeneration associated with Parkinson's disease.

Parkinson's & Movement disorders

Gene therapy shown to remove core component of Parkinson's disease

An international team led by Rush researcher Jeffrey Kordower, Ph.D., has moved a step closer to developing a treatment to clear brain cells of a protein that is an integral cause of Parkinson's disease. The team published ...

Parkinson's & Movement disorders

Study identifies chaperone protein implicated in Parkinson's disease

Reduced levels of a chaperone protein might have implications for the development and progression of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, according to new research from investigators ...

Parkinson's & Movement disorders

Study raises doubts on a previous theory of Parkinson's disease

Parkinson's disease was first described by a British doctor more than 200 years ago. The exact causes of this neurodegenerative disease are still unknown. In a study recently published in eLife, a team of researchers led ...

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