Medical research

Alternative splicing is crucial to muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

Genetics

G-quadruplex regulates breast cancer-associated gene

For breast cancer, carrying protein CD44s, instead of CD44v, has a survival advantage. Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development ...

Oncology & Cancer

Alternative splicing, an important mechanism for cancer

Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death. Thanks to the advances ...

Oncology & Cancer

How a non-coding RNA encourages cancer growth and metastasis

A mechanism that pushes a certain gene to produce a non-coding form of RNA instead of its protein-coding alternative can promote the growth of cancer, report researchers at the Medical University of South Carolina (MUSC) ...

Medical research

Change in protein production essential to muscle function

Researchers at Baylor College of Medicine have shed light on the process that guides the maturation of newborn muscles into adult, fully functional organs. In mice, they determined that a group of genes involved in calcium ...

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