Immunology

Research suggests new vaccine candidates for malaria

Researchers have shown that higher levels of Plasmodium falciparum antibodies are protective against severe malaria in children living in Papua New Guinea. Children who have higher levels of antibodies to a specific short ...

Immunology

Protective antibodies following malaria infection

No effective vaccine exists to date against the tropical disease malaria. Scientists from the German Cancer Research Center (DKFZ) have now studied how the human immune system responds to natural infection by the malaria ...

Diseases, Conditions, Syndromes

Postnatal identification of Zika virus peptides from saliva

For the first time, researchers are using proteomics to examine proteins and peptides in saliva in order to accurately detect exposure to Zika virus. With 70 countries and territories reporting evidence of mosquito-borne ...

Immunology

Solving medical 'cold cases' through genetics

Researchers have identified the genetic mutation responsible for one patient's serious health problems, finally solving a medical mystery that has endured for over 30 years. Thanks to this discovery, the researcher developed ...

Oncology & Cancer

Peptide mutants may help to identify vulnerability in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins ...

Medical research

A new angle on infertility

Scientists from the RIKEN BioResource Center in Tsukuba, Japan, have discovered that a single mutation in the beta-catenin gene, which codes a protein known to be deeply involved in a number of developmental and homeostatic ...

Genetics

Easy access to genetic testing

Frederick Sanger, who died recently at the age of 95, won two Nobel prizes in chemistry for his methods for sequencing proteins and DNA. Proteins were of more direct interest to many people because many disease-causing mutations ...

Genetics

Cancer: Lymphoma-linked risk factor identified

Follicular lymphoma is often caused by a translocation between chromosomes 14 and 18, resulting in the overexpression of a cancer-causing gene called BCL-2. A research team co-led by A*STAR scientists recently revealed another ...

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