Diseases, Conditions, Syndromes

The problem with antibiotics

We've all woken up with a sore throat that progresses to a runny nose by the next day. By the third day, we have a hacking cough, a pounding headache from the sinus congestion, and even fevers with chills. We drag ourselves ...

Cardiology

Azithromycin, levofloxacin up cardiac risk in study of veterans

(HealthDay)—Use of azithromycin or levofloxacin is associated with increased risks of death and cardiac arrhythmia compared with amoxicillin use, according to a study published in the March/April issue of the Annals of ...

Diseases, Conditions, Syndromes

High H. pylori cure rate for nonbismuth quadruple Tx

(HealthDay)—Optimized nonbismuth quadruple regimens, either hybrid or concomitant, have a cure rate of more than 90 percent for Helicobacter pylori (H. pylori) infections, according to a study published in the July issue ...

Diseases, Conditions, Syndromes

Antibiotics cut death rate for malnourished children

Severely malnourished children are far more likely to recover and survive when given antibiotics along with a therapeutic peanut-based food than children who are simply treated with the therapeutic food alone, researchers ...

Diseases, Conditions, Syndromes

New strep throat guidelines tackle antibiotic resistance

(HealthDay)—Doctors need to accurately diagnose and treat strep throat in order to avoid inappropriate use of antibiotics that can lead to drug-resistant bacteria, according to updated guidelines from the Infectious Diseases ...

Medications

Penicillin doses for children should be reviewed, say UK experts

A team of scientists and clinicians, led by researchers at King's College London and St George's, University of London, are calling for a review of penicillin dosing guidelines for children, as the current guidelines have ...

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Amoxicillin

Amoxicillin (INN), formerly amoxycillin (BAN), and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common antibiotics prescribed for children.

Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, which are resistant to a broad spectrum of β-lactam antibiotics, such as penicillin. For this reason, it is often combined with clavulanic acid, a β-lactamase inhibitor, and marketed under one name. This increases effectiveness by reducing its susceptibility to β-lactamase resistance.

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