Medications

Common diabetes drug reverses inflammation in the liver

The diabetes drug metformin—derived from a lilac plant that's been used medicinally for more than a thousand years—has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 ...

Medications

Scientists discover key regulator of neuron function and survival

Scientists studying neuronal energy metabolism found evidence that the loss of an important energy regulator called AMPK in neural stem cells or glial cells called astrocytes causes neuronal death in laboratory rodents. They ...

Medical research

Two enzymes control liver damage in NASH, study shows

As much as 12 percent of adults in the United States are living with nonalcoholic steatohepatitis (NASH), an aggressive condition that can lead to cirrhosis or liver cancer. After identifying a molecular pathway that allows ...

Oncology & Cancer

Research targets metformin as breast cancer prescription

Research conducted by Suresh Alahari, Ph.D., Professor of Biochemistry and Genetics at LSU Health New Orleans School of Medicine, has found that metformin, a commonly prescribed drug for Type 2 Diabetes, may be effective ...

Oncology & Cancer

Genetic 'whodunnit' for cancer gene solved

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery ...

Medical research

Nutrients may reduce blood glucose levels

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins. Scientists at Joslin Diabetes Center now have shown that one amino acid, alanine, ...

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