Alzheimer's disease & dementia

Study links inflammation to Alzheimer's disease development

Alzheimer's disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease ...

Neuroscience

What happens around an Alzheimer plaque?

The brains of people living with Alzheimer's are riddled with plaques: protein aggregates consisting mainly of amyloid beta. Despite decades of research, the real contribution of these plaques to the disease process is still ...

Alzheimer's disease & dementia

New imaging method sheds light on Alzheimer's disease

To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden ...

Alzheimer's disease & dementia

Brain changes may help track dementia, even before diagnosis

Even before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of dementia they have, according to a study published in the September 11, 2019, online ...

Alzheimer's disease & dementia

New drug targets early instigator of Alzheimer's disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...

Neuroscience

Tissue model reveals role of blood-brain barrier in Alzheimer's

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...

Alzheimer's disease & dementia

Direct toxic action of beta-amyloid identified

Hyperactive neurons in specific areas of the brain are believed to be an early perturbation in Alzheimer's disease. For the first time, a team from the Technical University of Munich (TUM) was able to explain the reasons ...

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