Alzheimer's disease & dementia

New drug targets early instigator of Alzheimer's disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...

Alzheimer's disease & dementia

An alternate theory for what causes Alzheimer's disease

Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures. But a University of ...

Neuroscience

Tissue model reveals role of blood-brain barrier in Alzheimer's

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...

Alzheimer's disease & dementia

Blood tests for Alzheimer's: Why new studies are encouraging

Many people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's disease, which afflicts at least 5.5 million people in the U.S. and brings tremendous burdens to families as ...

Neuroscience

A precise look at Alzheimer's proteins

A substance known as amyloid beta protein gets a lot of attention from scientists. Beta amyloid, as it's also called, is a normal brain protein found in everyone, but for an unknown reason it gunks up in the brains of patients ...

Alzheimer's disease & dementia

New Alzheimer therapy passes another important test

The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...

Alzheimer's disease & dementia

New compound shows promise in treatment of Alzheimer's

Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer's and even restores memories in mice, they report Jan. 2 in the journal Cell Reports.

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