Alzheimer's disease & dementia

Progress on early detection of Alzheimer's disease

Inside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amyloid-beta (Aβ) protein, which is vital for brain growth, can become tainted and destroy cells, which leads ...

Medical research

Unexpected protein could play role in common brain disorder

Scientists have known for years that amyloid fibrils—fibrous, ropelike structures formed by closely linked protein molecules—are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play ...

Diseases, Conditions, Syndromes

Unravelling the mysteries around type 2 diabetes

For more than 30 years, scientists have been trying to unravel the mystery of how a key biological molecule self assembles into a rogue protein-like substance known as amyloid, which is thought to play a role in the development ...

Oncology & Cancer

An amyloid link between Parkinson's disease and melanoma

On the surface, Parkinson's disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease ...

Neuroscience

Curcumin for amyloidosis and lipid metabolism—a novel insight

Curcumin is a polyphenol compound produced by plants of the Curcuma longa species and has been reported to have many physiological activities, which include anti-oxidation, anti-inflammatory, anti-cancer, and anti-amyloid ...

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