Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...
Apr 19, 2024
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Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the accumulation of misfolded protein ...
Feb 12, 2024
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A new study published in Nature Communications gives insights into the underlying mechanisms of the formation of protein clumps in Alzheimer's disease. The study, led by researchers from Karolinska Institutet, could pave ...
Feb 2, 2024
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Alzheimer's disease (AD) is a debilitating incurable disease that affects millions of patients worldwide. Deposits of amyloid beta (Aβ) amyloid in the brain is key to AD pathology at early stages. Apolipoprotein E (apoE) ...
Dec 7, 2023
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Researchers from the National Institutes of Natural Sciences and Nagoya City University have achieved a significant breakthrough by elucidating the structure of amyloid β (Aβ) bound to glycolipids on the surface of nerve ...
Aug 7, 2023
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Amyloid deposition is a hallmark of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The deposition process is described as a sigmoidal curve in which the misfolded proteins assemble ...
Aug 2, 2023
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Dialysis is a lifesaving technique that artificially filters blood; however, it has some harmful side effects. Now, researchers from Japan have found that monitoring a normal blood component could help prevent one of the ...
Oct 6, 2022
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Scientists at UCLA have used a molecule found in green tea to identify additional molecules that could break up protein tangles in the brain thought to cause Alzheimer's and similar diseases.
Sep 20, 2022
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AL amyloidosis is a life-threatening disease related to bone marrow cancer and multiple myeloma. It is caused when a person's antibody-producing white blood cells (i.e. plasma cells) do not function properly and generate ...
Jul 14, 2022
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Inside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amyloid-beta (Aβ) protein, which is vital for brain growth, can become tainted and destroy cells, which leads ...
Jun 14, 2022
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