Alzheimer's disease & dementia

Why BACE inhibitors may be failing Alzheimer's trials

Completely blocking the activity of an enzyme that produces amyloid plaques observed in Alzheimer's disease (AD) interferes with the regulation of new neurons generated in the adult hippocampus, according to a study of mice ...

Medical research

New mutation in amyloid diseases discovered

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called ...

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