Diseases that run in families usually have genetic causes. Some are genetic mutations that directly cause the disease if inherited. Others are risk genes that affect the body in a way that increases the chance someone will ...
Sep 15, 2023
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Trial results of a new drug to treat Alzheimer's disease, donanemab, shows it can slow cognitive decline by 35%. The drug has been hailed as a "turning point" in Alzheimer's treatment.
Jul 19, 2023
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Last year, the FDA gave accelerated approval of the antibody aducanumab (marketed as Aduhelm by Biogen) for the treatment of Alzheimer's disease. The approval was based solely on a presumed reduction in the amount of the ...
Nov 16, 2022
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In recent debate over the FDA's approval of the Alzheimer's drug aducanumab, we've heard a lot about the "amyloid hypothesis." In that context, it's refreshing to learn about a model of Alzheimer's neurodegeneration that ...
Jun 29, 2021
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For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.
Mar 18, 2020
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For decades, the field of Alzheimer's research has been dominated by a major hypothesis: that a build-up of beta amyloid (amyloid-β) in the brain causes Alzheimer's disease. However, despite years of research and billions ...
Oct 29, 2018
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A hypothesis which has been the standard way of explaining how the body develops Alzheimer's Disease for almost 30 years is flawed, according to a University of Manchester biologist.
Oct 16, 2018
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Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein ...
May 22, 2018
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Alzheimer's disease, a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure.
Jan 23, 2018
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Despite a 99 percent failure rate and another major setback recently, Alzheimer's researchers are plowing ahead with hundreds of experiments - and a boost in federal money - to try to a crack a deadly disease that has flummoxed ...
Feb 10, 2017
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