Alzheimer's disease & dementia

In search of an Alzheimer's cure

For decades, the field of Alzheimer's research has been dominated by a major hypothesis: that a build-up of beta amyloid (amyloid-β) in the brain causes Alzheimer's disease. However, despite years of research and billions ...

Alzheimer's disease & dementia

Hypothesis underpinning dementia research 'flawed'

A hypothesis which has been the standard way of explaining how the body develops Alzheimer's Disease for almost 30 years is flawed, according to a University of Manchester biologist.

Alzheimer's disease & dementia

Trying to solve the Alzheimer's puzzle

Despite a 99 percent failure rate and another major setback recently, Alzheimer's researchers are plowing ahead with hundreds of experiments - and a boost in federal money - to try to a crack a deadly disease that has flummoxed ...

Neuroscience

New findings contradict dominant theory in Alzheimer's disease

For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...