Alzheimer's disease & dementia

A new strategy required in the search for Alzheimer's drugs?

In the search for medication against Alzheimer's disease, scientists have focused – among other factors – on drugs that can break down Amyloid beta (A-beta). After all, it is the accumulation of A-beta that causes the ...

Alzheimer's disease & dementia

Carmustine decreases amyloid beta plaques

Long term treatment by carmustine, a chemical relative of mustard gas and already used to treat some types of brain cancer, can decrease the amount of amyloid β and number of amyloid plaques in a mouse model of Alzheimer's ...

Alzheimer's disease & dementia

Discovery sheds light on Alzheimer's mystery

(Medical Xpress)—In 1906, when Alois Alzheimer discovered the neurodegenerative disease that would later be named for him, he saw amyloid-beta plaques and neurofibrillary tangles inside the brain. Several decades later, ...

Alzheimer's disease & dementia

'Natural' protection against Alzheimer’s disease

deCODE Genetics, together with their colleagues from the pharmaceutical company Genentech, reported today in the journal Nature the discovery of a variant of the amyloid precursor protein (APP) gene that confers protection ...

Neuroscience

Characterizing a toxic offender

The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory deficits. Now, ...

page 7 from 9