Alzheimer's disease & dementia

New Alzheimer therapy passes another important test

The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...

Alzheimer's disease & dementia

Alzheimer's disease is a 'double-prion disorder,' study shows

Two proteins central to the pathology of Alzheimer's disease act as prions—misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape—according to new ...

Alzheimer's disease & dementia

Scientists propose new theory on Alzheimer's, amyloid connection

Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, which causes problems with ...

Neuroscience

Unraveling the mysteries of multiple sclerosis

Leiden chemists discovered a new mechanism which might explain how multiple sclerosis shifts to a more severe form. Their findings contribute to unraveling the mysterious course of the disease. They have published their findings ...

Alzheimer's disease & dementia

Immune cell defect stimulates Alzheimer's

Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...

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