Drugs like enzalutamide that inhibit male hormones from activating the androgen receptor have been used to treat advanced prostate cancer for more than a decade. While successful in most cases, these drugs can eventually ...
Sep 15, 2022
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Research led by Suresh Alahari, Ph.D., Professor of Biochemistry at LSU Health New Orleans schools of Medicine and Graduate Studies, suggests a combination of drugs already approved by the FDA for other cancers may be effective ...
Jun 29, 2022
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Prostate cancer is the most common cancer among men in the United States. Many patients can live long lives due to early detection and treatment with androgen deprivation therapy. However, despite the benefits of this therapy, ...
Jun 15, 2022
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Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers from The University of Texas MD Anderson Cancer Center showed in a study published today ...
Jun 15, 2022
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A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.
May 11, 2022
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Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor—the protein inside of cells that responds to male-typical hormones like testosterone. Their ...
Apr 20, 2022
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A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer. The assay could be used to identify new drugs to treat ...
Apr 6, 2022
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Resistance or strength training protects against the development of muscle pain in mice—and does so by activating androgen receptors, reports a basic science study in PAIN, the official publication of the International ...
Mar 31, 2022
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Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies.
Nov 5, 2021
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The doctoral thesis of A. B. M. Kaiser Manjur, M.Sc., at the Faculty of Health Sciences, provides novel insights into two medically important transcription factors (TFs), glucocorticoid receptor (GR) and androgen receptor ...
Aug 18, 2021
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