Recent research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by ...
Apr 10, 2024
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A research paper published today in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator that stimulates the male sex hormone receptor, has anti-tumor effects in estrogen receptor-positive ...
Feb 8, 2024
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It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells. A recent study published in Communications Biology by the ...
Feb 2, 2024
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Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and control the rate at which ...
Dec 4, 2023
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Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow—advancements that can help explain why some ...
Dec 4, 2023
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Men with a particular genetic subtype of the steroid biosynthesis enzyme HSD3B1 may exhibit resistance to combined radiation and hormone therapy for prostate cancer, according to new Cleveland Clinic-led research published ...
Nov 20, 2023
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Research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered that altering certain molecular interactions could yield new strategies for treating ...
Oct 6, 2023
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Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex hormones drive differences in male ...
Sep 5, 2023
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At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors—which bind to hormones like testosterone—and SARS-CoV-2 ...
Aug 18, 2023
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Polycystic ovary syndrome (PCOS) is a common hormone disorder in women. Studies have shown that the change in hormones is accompanied by variations in immunological B cells. Researchers at Karolinska Institutet have now established ...
Jul 6, 2023
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