Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment ...
Mar 19, 2019
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Testosterone is blamed for sex drive and aggression, but it also appears to be critical for telling the brain "enough!" when it comes to those behaviors. A molecule called TRPM8 (pronounced trip-M-8) embedded in the surface ...
Mar 1, 2019
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Researchers have discovered a new use for an old drug as a potential treatment for prostate cancer. The findings are published in the journal The Prostate.
Oct 3, 2018
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Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation ...
Jul 19, 2018
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In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these hormones have to bind to androgen ...
Jul 19, 2018
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Two blood tests can predict which subset of men with advanced prostate cancer will likely not benefit from anti-androgen therapies, providing doctors and patient added clarity on treatment options, according to a study led ...
Jun 5, 2018
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The dark matter of the human genome may shed light on how the hormone androgen impacts prostate cancer.
May 28, 2018
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Fifteen years ago, Michael Jung was already an eminent scientist when his wife asked him a question that would change his career, and extend the lives of many men with a particularly lethal form of prostate cancer.
Mar 16, 2018
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St. Jude Children's Research Hospital scientists have demonstrated in mouse studies that the neurological disease spinal bulbar muscular atrophy (SBMA) can be successfully treated with drugs. The finding paves the way for ...
Mar 15, 2018
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Researchers have identified a new regulator of vitamin D metabolism that could be targeted to reduce the risk of osteoporosis in men undergoing prostate cancer therapy, according to a study published in the Journal of Molecular ...
Jan 31, 2018
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