Neuroscience

General anesthesia hijacks sleep circuitry to knock you out

The discovery of general anesthesia 170 years ago was a medical miracle, enabling millions of patients to undergo invasive, life-saving surgeries without pain. Yet despite decades of research, scientists still don't understand ...

Cardiology

Operator-directed sedation seems safe in peds cardiac cath

(HealthDay)—For carefully selected pediatric patients, operator-directed sedation (ODS) for congenital cardiac catheterization procedures is not associated with an increased risk for adverse events and may reduce case time ...

Surgery

Peripheral nerve block may cut opioid use after amputation

(HealthDay)—Peripheral nerve blockade with regular local anesthetic and liposomal bupivacaine is associated with lower oral morphine equivalent (OME) use at 72 hours after major lower extremity amputation (MLEA), according ...

Surgery

Awake lumbar interbody fusion

As one can infer from the article title, "Endoscopic transforaminal lumbar interbody fusion without general anesthesia: operative and clinical outcomes in 100 consecutive patients with a minimum 1-year follow-up," by John ...

Cardiology

Volatile anesthetics do not reduce deaths in elective CABG

(HealthDay)—For patients undergoing elective coronary artery bypass grafting (CABG), there is no significant difference in deaths at one year with anesthesia with a volatile agent versus total intravenous anesthesia, according ...

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Anesthesia

Anesthesia, or anaesthesia (see spelling differences; from Greek αν-, an-, "without"; and αἲσθησις, aisthēsis, "sensation"), has traditionally meant the condition of having sensation (including the feeling of pain) blocked or temporarily taken away. This allows patients to undergo surgery and other procedures without the distress and pain they would otherwise experience. The word was coined by Oliver Wendell Holmes, Sr. in 1846. Another definition is a "reversible lack of awareness", whether this is a total lack of awareness (e.g. a general anaesthetic) or a lack of awareness of a part of the body such as a spinal anaesthetic or another nerve block would cause. Anesthesia is a pharmacologically induced reversible state of amnesia, analgesia, loss of consciousness, loss of skeletal muscle reflexes and decreased stress response.

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