Cancer

Researchers identify receptor to slow breast cancer metastasis

In a research study published in the journal Oncogene, scientists from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that by therapeutically targeting the receptor for advanced ...

Diabetes

Finding new targets to treat vascular damage

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis. There are no established drugs to improve angiogenesis in ...

Medical research

Going to 'Wars' against cancer and heart disease

In a study conducted by Duke-NUS Medical School (Duke-NUS) and the National Heart Centre Singapore (NHCS), researchers discovered a new gene that controls blood vessel formation. This work presents a possible new drug target ...

Cancer

Hybrid cells cause chaos around cancers

Rice University researchers have built a simulation to show how cancerous tumors manipulate blood-vessel growth for their own benefit.

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Angiogenesis

Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood vessels by the splitting of exisiting ones.

Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in granulation tissue. However, it is also a fundamental step in the transition of tumors from a dormant state to a malignant one, leading to the use of angiogenesis inhibitors. The identification of an angiogenic diffusible factor derived from tumors was made initially by Greenblatt and Shubik in 1968.

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